دورية أكاديمية
Experimental and Theoretical DFT Study of Cu(I)/ N , N -Disubstituted- N '-acylthioureato Anticancer Complexes: Actin Cytoskeleton and Induction of Death by Apoptosis in Triple-Negative Breast Tumor Cells.
العنوان: | Experimental and Theoretical DFT Study of Cu(I)/ N , N -Disubstituted- N '-acylthioureato Anticancer Complexes: Actin Cytoskeleton and Induction of Death by Apoptosis in Triple-Negative Breast Tumor Cells. |
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المؤلفون: | Leite CM; Departamento de Química, Universidade Federal de São Carlos - UFSCar, São Carlos, São Paulo 13565-905, Brazil., Honorato J; Departamento de Química, Universidade Federal de São Carlos - UFSCar, São Carlos, São Paulo 13565-905, Brazil., Martin ACBM; Hospital de Amor de Barretos, Barretos, São Paulo 14784-400, Brazil., Silveira RG; Instituto Federal Goiano, Campus Ceres, Ceres, Goiás 76300000, Brazil., Colombari FM; Centro Nacional de Pesquisa em Energia e Materiais, Laboratório Nacional de Biorrenováveis, Campinas, São Paulo 13083-970, Brazil., Amaral JC; Departamento de Química, Universidade Federal de São Carlos - UFSCar, São Carlos, São Paulo 13565-905, Brazil., Costa AR; Departamento de Química, Universidade Federal de São Carlos - UFSCar, São Carlos, São Paulo 13565-905, Brazil., Cominetti MR; Departamento de Gerontologia, Universidade Federal de São Carlos - UFSCar, São Carlos, São Paulo 13565-905, Brazil., Plutín AM; Laboratório de Síntesis Orgánica, Facultad de Química, Universidad de La Habana - UH, Habana 10400, Cuba., de Aguiar D; Instituto de Química, Universidade Federal de Goiás, Goiania, Goiás 74690900, Brazil., Vaz BG; Instituto de Química, Universidade Federal de Goiás, Goiania, Goiás 74690900, Brazil., Batista AA; Departamento de Química, Universidade Federal de São Carlos - UFSCar, São Carlos, São Paulo 13565-905, Brazil.; Instituto de Química, Universidade Federal de Goiás, Goiania, Goiás 74690900, Brazil. |
المصدر: | Inorganic chemistry [Inorg Chem] 2022 Jan 10; Vol. 61 (1), pp. 664-677. Date of Electronic Publication: 2021 Dec 20. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 0366543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-510X (Electronic) Linking ISSN: 00201669 NLM ISO Abbreviation: Inorg Chem |
أسماء مطبوعة: | Original Publication: [Easton, Pa.] American Chemical Society. |
مواضيع طبية MeSH: | Apoptosis*/drug effects , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Copper*/chemistry , Copper*/pharmacology , Density Functional Theory* , Triple Negative Breast Neoplasms*/pathology , Triple Negative Breast Neoplasms*/drug therapy , Coordination Complexes*/pharmacology , Coordination Complexes*/chemistry , Coordination Complexes*/chemical synthesis , Drug Screening Assays, Antitumor* , Actin Cytoskeleton*/drug effects , Actin Cytoskeleton*/metabolism, Humans ; Thiourea/pharmacology ; Thiourea/chemistry ; Cell Proliferation/drug effects ; Molecular Structure ; Cell Line, Tumor |
مستخلص: | Six complexes with the general formula [Cu(acylthioureato)(PPh |
المشرفين على المادة: | 0 (Antineoplastic Agents) 789U1901C5 (Copper) 0 (Coordination Complexes) GYV9AM2QAG (Thiourea) |
تواريخ الأحداث: | Date Created: 20211220 Date Completed: 20240724 Latest Revision: 20240724 |
رمز التحديث: | 20240726 |
DOI: | 10.1021/acs.inorgchem.1c03389 |
PMID: | 34928593 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1520-510X |
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DOI: | 10.1021/acs.inorgchem.1c03389 |