دورية أكاديمية
Diffuse Alopecia and Thyroid Atrophy in Sheep.
| العنوان: | Diffuse Alopecia and Thyroid Atrophy in Sheep. |
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| المؤلفون: | Sampaio RAG; Graduate Program in Animal Science, Universidade Federal da Paraíba, Areia 58397-000, PB, Brazil., Riet-Correa F; Graduate Program in Animal Science, Universidade Federal da Paraíba, Areia 58397-000, PB, Brazil.; Graduate Program in Animal Science in the Tropics, Universidade Federal da Bahia, Salvador 40170-110, BA, Brazil., Barbosa FMS; Graduate Program in Animal Science, Universidade Federal da Paraíba, Areia 58397-000, PB, Brazil., de Gois DD; Laboratory of Veterinary Pathology, Universidade Federal da Paraíba, Areia 58397-000, PB, Brazil., Lima RC; Laboratory of Veterinary Pathology, Universidade Federal da Paraíba, Areia 58397-000, PB, Brazil., da Silva IG; Laboratory of Veterinary Pathology, Universidade Federal da Paraíba, Areia 58397-000, PB, Brazil., da Silva VM; Laboratory of Veterinary Pathology, Universidade Federal da Paraíba, Areia 58397-000, PB, Brazil., Oliveira AM; Graduate Program in Animal Science, Universidade Federal da Paraíba, Areia 58397-000, PB, Brazil., Simões SVD; Graduate Program in Animal Science, Universidade Federal da Paraíba, Areia 58397-000, PB, Brazil., Lucena RB; Graduate Program in Animal Science, Universidade Federal da Paraíba, Areia 58397-000, PB, Brazil.; Laboratory of Veterinary Pathology, Universidade Federal da Paraíba, Areia 58397-000, PB, Brazil. |
| المصدر: | Animals : an open access journal from MDPI [Animals (Basel)] 2021 Dec 10; Vol. 11 (12). Date of Electronic Publication: 2021 Dec 10. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Molecular Diversity Preservation International Country of Publication: Switzerland NLM ID: 101635614 Publication Model: Electronic Cited Medium: Print ISSN: 2076-2615 (Print) Linking ISSN: 20762615 NLM ISO Abbreviation: Animals (Basel) Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Basel, Switzerland : Molecular Diversity Preservation International, 2011- |
| مستخلص: | Thyroid dysfunction substantially affects the quality of life due to its association with various disorders in different organs. A low intake of selenium and zinc can predispose to thyroid alterations, resulting in hypothyroidism. A deficiency of selenium and zinc causes direct and indirect skin lesions, both by the action of free radicals on the skin and by thyroid dysfunction. The aim of this study was to describe natural cases of diffuse alopecia and thyroid abnormalities in sheep with selenium and zinc deficiency. Five adult sheep presented marked and diffuse alopecia, and the residual hairs were dry and brittle. The skin was thick and crusty, with marked peeling. The triiodothyronine (T3) and thyroxine (T4) serum concentrations were below reference values for the species. Zinc and Se concentrations were low in both the serum and liver. During necropsy, cachexia associated with serous fat atrophy was observed, and the thyroid glands showed marked atrophy. Microscopically, the thyroid presented multifocal to coalescent atrophy, with atrophied and dilated follicles, macrophage infiltration, and the presence of fibrous connective tissue. The skin revealed hyperkeratosis and edema. It is concluded that thyroid atrophy, alopecia, and hyperkeratosis are associated with low serum and liver concentrations of zinc and selenium in sheep. |
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| معلومات مُعتمدة: | PVN13494-2020 Dean of Graduate Studies and Dean of Research at the Universidade Federal da Paraíba |
| فهرسة مساهمة: | Keywords: dermatoses; endocrine disease; hypothyroidism; mineral deficiency; ruminants |
| تواريخ الأحداث: | Date Created: 20211224 Latest Revision: 20211228 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC8698121 |
| DOI: | 10.3390/ani11123530 |
| PMID: | 34944304 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2076-2615 |
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| DOI: | 10.3390/ani11123530 |