دورية
Exercise-induced beige adipogenesis of iWAT in Cidea reporter mice.
| العنوان: | Exercise-induced beige adipogenesis of iWAT in Cidea reporter mice. |
|---|---|
| المؤلفون: | Kim JK; Laboratory of Developmental Biology and Genomics, College of Veterinary Medicine, BK21 Plus Program for Advanced Veterinary Science, Research Institute for Veterinary Science Seoul National University, Seoul 08826; Korea Mouse Phenotyping Center (KMPC), Seoul 08826, Korea., Go HS; Korea Mouse Phenotyping Center (KMPC), Seoul 08826, Korea., Kim SP; Korea Mouse Phenotyping Center (KMPC), Seoul 08826, Korea., Kim IY; Laboratory of Developmental Biology and Genomics, College of Veterinary Medicine, BK21 Plus Program for Advanced Veterinary Science, Research Institute for Veterinary Science Seoul National University, Seoul 08826; Korea Mouse Phenotyping Center (KMPC), Seoul 08826, Korea., Lee YH; Korea Mouse Phenotyping Center (KMPC), Seoul 08826; College of Pharmacy, Seoul National University, Seoul 08826, Korea., Oh SH; Korea Mouse Phenotyping Center (KMPC), Seoul 08826; College of Pharmacy, Gachon University, Incheon 21936, Korea., Lee H; Korea Mouse Phenotyping Center (KMPC), Seoul 08826; National Cancer Center, Goyang 10408, Korea., Seong JK; Laboratory of Developmental Biology and Genomics, College of Veterinary Medicine, BK21 Plus Program for Advanced Veterinary Science, Research Institute for Veterinary Science Seoul National University, Seoul 08826; Korea Mouse Phenotyping Center (KMPC), Seoul 08826, Korea. |
| المصدر: | BMB reports [BMB Rep] 2022 Apr; Vol. 55 (4), pp. 187-191. |
| نوع المنشور: | News |
| اللغة: | English |
| بيانات الدورية: | Publisher: Korean Society for Biochemistry and Molecular Biology Country of Publication: Korea (South) NLM ID: 101465334 Publication Model: Print Cited Medium: Internet ISSN: 1976-670X (Electronic) Linking ISSN: 19766696 NLM ISO Abbreviation: BMB Rep Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Seoul : Korean Society for Biochemistry and Molecular Biology |
| مواضيع طبية MeSH: | Adipogenesis* , Adipose Tissue, White*, Animals ; Apoptosis Regulatory Proteins ; Mice ; Obesity ; Signal Transduction |
| مستخلص: | Obesity is caused by an imbalance between energy intake and energy expenditure. Exercise is attracting attention as one of the ways to treat obesity. Exercise induces 'beige adipogenesis' in white adipose tissue, increasing total energy expenditure via energy dissipation in the form of heat. Also, beige adipogenesis can be induced by treatment with a beta-adrenergic receptor agonist. We developed a Cidea-dual reporter mouse (Cidea-P2ALuc2-T2A-tdTomato, Luciferase/tdTomato) model to trace and measure beige adipogenesis in vivo. As a result, both exercise and injection of beta-adrenergic receptor agonist induced beige adipogenesis and was detected through fluorescence and luminescence. We confirmed that exercise and beta-adrenergic receptor agonist induce beige adipogenesis in Cidea-dual reporter mouse, which will be widely used for detecting beige adipogenesis in vivo. [BMB Reports 2022; 55(4): 187-191]. |
| التعليقات: | Erratum in: BMB Rep. 2022 Jul;55(7):360. (PMID: 35892132) |
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| المشرفين على المادة: | 0 (Apoptosis Regulatory Proteins) 0 (Cidea protein, mouse) |
| تواريخ الأحداث: | Date Created: 20220110 Date Completed: 20220428 Latest Revision: 20220727 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC9058471 |
| PMID: | 35000670 |
| قاعدة البيانات: | MEDLINE |
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