دورية أكاديمية
أعرض في EDS

Associations between Sjögren Syndrome, Sociodemographic Factors, Comorbid Conditions, and Scleritis in a Taiwanese Population-Based Study.

التفاصيل البيبلوغرافية
العنوان: Associations between Sjögren Syndrome, Sociodemographic Factors, Comorbid Conditions, and Scleritis in a Taiwanese Population-Based Study.
المؤلفون: Jan RL; Department of Pediatrics, Chi Mei Medical Center, Liouying, Tainan 736, Taiwan.; Graduate Institute of Medical Sciences, College of Health Sciences, Chang Jung Christian University, Tainan 711, Taiwan., Ho CH; Department of Medical Research, Chi Mei Medical Center, Tainan 710, Taiwan.; Department of Hospital and Health Care Administration, Chia Nan University of Pharmacy and Science, Tainan 717, Taiwan., Wang JJ; Department of Medical Research, Chi Mei Medical Center, Tainan 710, Taiwan.; Department of Anesthesiology, Chi Mei Medical Center, Tainan 710, Taiwan., Tseng SH; Department of Ophthalmology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan.; Department of Ophthalmology, Chi Mei Medical Center, Tainan 710, Taiwan., Chang YS; Graduate Institute of Medical Sciences, College of Health Sciences, Chang Jung Christian University, Tainan 711, Taiwan.; Department of Ophthalmology, Chi Mei Medical Center, Tainan 710, Taiwan.
المصدر: Journal of personalized medicine [J Pers Med] 2022 Jan 14; Vol. 12 (1). Date of Electronic Publication: 2022 Jan 14.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101602269 Publication Model: Electronic Cited Medium: Print ISSN: 2075-4426 (Print) Linking ISSN: 20754426 NLM ISO Abbreviation: J Pers Med Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI AG, 2011-
مستخلص: This nationwide, population-based, retrospective, matched case-control study included 111,960 newly diagnosed patients with scleritis who were identified by the International Classification of Diseases, Ninth Revision, Clinical Modification code 379.0, selected from the Taiwan National Health Insurance Research Database. Demographic characteristics, Sjögren syndrome, and comorbid conditions within 1 year before the scleritis diagnosis were examined using univariate logistic regression analyses, and a paired t -test was used for continuous variables. Adjusted logistic regression was used to compare the prognosis odds ratio (OR) of the patients with scleritis with the controls. After adjustment for confounders, patients with Sjögren syndrome were remarkably more likely to have scleritis than the controls (OR = 33.53, 95% confidence interval (CI) = 27.43-40.97, p < 0.001). Other conditions found to have increased odds of scleritis included post ocular pterygium, glaucoma, and scleral surgery (OR  =  4.01, 95% CI  =  3.64-4.43; OR  =  3.16, 95% CI  =  2.24-4.47; OR  =  6.83, 95% CI  =  5.34-8.74, respectively); systemic infections, such as syphilis, tuberculosis, and a human herpes viral infection (OR  =  4.01, 95% CI  =  2.93-5.50; OR  =  2.24, 95% CI  =  1.94-2.58; OR  =  8.54, 95% CI  =  8.07-9.03, respectively); and systemic diseases, such as rheumatoid arthritis, granulomatous vasculitis, systemic lupus erythematosus, ankylosing spondylitis, and gout (OR  =  2.93, 95% CI  =  2.66-3.23; OR  =  7.37, 95% CI  =  3.91-13.88; OR  =  3.18, 95% CI  =  2.63-3.85; OR  =  5.57, 95% CI  =  4.99-6.22; OR  =  2.84, 95% CI  =  2.72-2.96, respectively). The results strongly support an association between Sjögren syndrome, post ocular surgery, systemic infection disease, systemic autoimmune disease, and scleritis.
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فهرسة مساهمة: Keywords: Sjögren syndrome; Taiwan Longitudinal Health Insurance Database; case–control study; scleritis
تواريخ الأحداث: Date Created: 20220121 Latest Revision: 20220128
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC8778815
DOI: 10.3390/jpm12010105
PMID: 35055420
قاعدة البيانات: MEDLINE
الوصف
تدمد:2075-4426
DOI:10.3390/jpm12010105