دورية أكاديمية

Effect of Photodynamic Therapy on Halitosis: A Systematic Review of Randomized Controlled Trials.

التفاصيل البيبلوغرافية
العنوان: Effect of Photodynamic Therapy on Halitosis: A Systematic Review of Randomized Controlled Trials.
المؤلفون: Motta PB; Postgraduation Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), Sao Paulo 01504-001, SP, Brazil., Motta LJ; Postgraduation Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), Sao Paulo 01504-001, SP, Brazil., Campos TM; Postgraduation Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), Sao Paulo 01504-001, SP, Brazil., Gonçalves MLL; Postgraduation Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), Sao Paulo 01504-001, SP, Brazil.; Postgraduation Program in Health and Environment, Universidade Metropolitana de Santos (UNIMES), Santos 11045-002, SP, Brazil., Santos EM; Postgraduation Program in Health and Environment, Universidade Metropolitana de Santos (UNIMES), Santos 11045-002, SP, Brazil., Martimbianco ALC; Postgraduation Program in Health and Environment, Universidade Metropolitana de Santos (UNIMES), Santos 11045-002, SP, Brazil., de Andrade DJC; School of Dentistry, University of Porto, 4099-002 Porto, Portugal., Mesquita-Ferrari RA; Postgraduation Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), Sao Paulo 01504-001, SP, Brazil., Fernandes KPS; Postgraduation Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), Sao Paulo 01504-001, SP, Brazil., Horliana ACRT; Postgraduation Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), Sao Paulo 01504-001, SP, Brazil., Bussadori SK; Postgraduation Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), Sao Paulo 01504-001, SP, Brazil.
المصدر: Sensors (Basel, Switzerland) [Sensors (Basel)] 2022 Jan 08; Vol. 22 (2). Date of Electronic Publication: 2022 Jan 08.
نوع المنشور: Journal Article; Review; Systematic Review
اللغة: English
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101204366 Publication Model: Electronic Cited Medium: Internet ISSN: 1424-8220 (Electronic) Linking ISSN: 14248220 NLM ISO Abbreviation: Sensors (Basel) Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI, c2000-
مواضيع طبية MeSH: Halitosis*/diagnosis , Halitosis*/drug therapy , Photochemotherapy*, Adolescent ; Adult ; Humans ; Randomized Controlled Trials as Topic
مستخلص: Background: This systematic review aimed to assess the effectiveness and safety of aPDT for the treatment of halitosis.
Methods: Search strategies were conducted in October 2021 without language or data restrictions, on the following databases: MEDLINE, EMBASE, CENTRAL, LILACS and BBO, as well as a manual search. Randomized clinical trials (RCTs) with parallel design were considered for inclusion, assessing individuals (adolescents and adults) with a clinical diagnosis of halitosis treated with photodynamic therapy (aPDT). Primary outcomes assessed were halitosis measurements, adverse events and quality of life. The risk of bias for each included study was evaluated with the Cochrane Risk of Bias tool and the certainty of the body of the evidence was assessed with the GRADe approach.
Results: Six RCTs (total of 225 participants) were included and due to clinical diversities it was not possible to group the outcome data in meta-analyses. Based on very low-certainty evidence (GRADE) the results showed that, when compared to tongue scraper, aPDT seems to promote a little to no difference in reducing halitosis and in the microbiological analysis. No adverse events were reported. Considering aPDT combined with tongue scraper, better outcome results were observed when compared to tongue scraper alone.
Conclusions: Based on very low-certainty evidence, the findings of this review are uncertain about the effects of aPDT for halitosis control. Further RCTs with higher number of participants and long term assessments need to be conducted to support the use of this intervention. The protocol was registered in the PROSPERO database (number: CRD42020215319) on 19 November 2020-retrospectively registered.
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معلومات مُعتمدة: 2019/14229-6 São Paulo Research Foundation (FAPESP); 306577/2020-8 Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); 88887.646066/2021-00 Coordenação de Aperfeicoamento de Pessoal de Nível Superior (CAPES)
فهرسة مساهمة: Keywords: halitosis; laser; photodynamic therapy; systematic review
تواريخ الأحداث: Date Created: 20220122 Date Completed: 20220125 Latest Revision: 20231103
رمز التحديث: 20231103
مُعرف محوري في PubMed: PMC8780921
DOI: 10.3390/s22020469
PMID: 35062433
قاعدة البيانات: MEDLINE