دورية أكاديمية
أعرض في EDS

Correlation of Gastrointestinal Symptoms at Initial Presentation with Clinical Outcomes in Hospitalized COVID-19 Patients: Results from a Large Health System in the Southern USA.

التفاصيل البيبلوغرافية
العنوان: Correlation of Gastrointestinal Symptoms at Initial Presentation with Clinical Outcomes in Hospitalized COVID-19 Patients: Results from a Large Health System in the Southern USA.
المؤلفون: Patel HK; Department of Internal Medicine, Ochsner Clinic Foundation, 1514 Jefferson Hwy, New Orleans, LA, 70121, USA. patelhk.md@gmail.com., Kovacic R; Department of Gastroenterology, Ochsner Clinic Foundation, New Orleans, USA., Chandrasekar VT; Department of Gastroenterology, Mayo Clinic Arizona, Scottsdale, USA., Patel SC; School of Public Health, Louisiana State University Shreveport, Shreveport, USA., Singh M; Ochsner Clinical School, University of Queensland, New Orleans, USA., Le Cam E; Ochsner Clinical School, University of Queensland, New Orleans, USA., Burton JH; Center for Outcomes and Health Services Research, Ochsner Health System, New Orleans, USA., Ray A; Department of Gastroenterology, Ochsner Clinic Foundation, New Orleans, USA., Shah JN; Department of Gastroenterology, Ochsner Clinic Foundation, New Orleans, USA.
المصدر: Digestive diseases and sciences [Dig Dis Sci] 2022 Nov; Vol. 67 (11), pp. 5034-5043. Date of Electronic Publication: 2022 Feb 07.
نوع المنشور: Multicenter Study; Journal Article
اللغة: English
بيانات الدورية: Publisher: Springer Science + Business Media Country of Publication: United States NLM ID: 7902782 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2568 (Electronic) Linking ISSN: 01632116 NLM ISO Abbreviation: Dig Dis Sci Subsets: MEDLINE
أسماء مطبوعة: Publication: 2005- : New York, NY : Springer Science + Business Media
Original Publication: New York, Plenum Pub. Corp.
مواضيع طبية MeSH: COVID-19*/complications , COVID-19*/therapy , Gastrointestinal Diseases*/diagnosis , Gastrointestinal Diseases*/epidemiology, Female ; Humans ; Middle Aged ; Aged ; SARS-CoV-2 ; Retrospective Studies ; Cohort Studies ; Nausea/epidemiology ; Nausea/etiology ; Vomiting/epidemiology ; Vomiting/etiology ; Diarrhea/epidemiology ; Diarrhea/etiology ; Abdominal Pain/epidemiology ; Abdominal Pain/etiology
مستخلص: Background: We aimed to understand the association of gastrointestinal (GI) symptoms at initial presentation with clinical outcomes during COVID-19 hospitalization.
Methods: This retrospective, multicenter cohort study included consecutive hospitalized COVID-19 patients from a single, large health system. The presence of GI symptoms was assessed at initial presentation and included one or more of the following: nausea, vomiting, diarrhea and abdominal pain. Patients were divided into three cohorts: Only GI symptoms, GI and non-GI symptoms and only non-GI symptoms. The primary outcome was association of GI symptoms with mortality. Secondary outcomes included prevalence of GI symptoms and survival analysis.
Results: A total of 1672 COVID-19 patients were hospitalized (mean age: 63 ± 15.8 years, females: 50.4%) in our system during the study period. 40.7% patients had at least one GI symptom (diarrhea in 28.3%, nausea/vomiting in 23%, and abdominal pain in 8.8% patients), and 2.6% patients had only GI symptoms at initial presentation. Patients presenting with GI symptoms (with or without non-GI symptoms) had a lower mortality rate compared to patients presenting with only non-GI symptoms (20% vs. 26%; p < 0.05). The time from hospitalization to being discharged was less for patients presenting with only GI symptoms (7.4 days vs. > 9 days, p < 0.0014). After adjusting for other factors, the presence of GI symptoms was not associated with mortality (p > 0.05).
Conclusion: Among a hospitalized COVID-19 positive Southern US population, 41% patients presented with either diarrhea, nausea, vomiting or abdominal pain initially. The presence of GI symptoms has no association with in-hospital all-cause mortality.
(© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
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فهرسة مساهمة: Keywords: COVID-19; Coronavirus; Diarrhea; GI; Mortality; Outcomes; SARS-CoV-2
تواريخ الأحداث: Date Created: 20220207 Date Completed: 20221025 Latest Revision: 20230104
رمز التحديث: 20240829
مُعرف محوري في PubMed: PMC8818361
DOI: 10.1007/s10620-022-07384-0
PMID: 35128607
قاعدة البيانات: MEDLINE
الوصف
تدمد:1573-2568
DOI:10.1007/s10620-022-07384-0