دورية أكاديمية
أعرض في EDS

Gut microbiota modulation by jabuticaba peel and its effect on glucose metabolism via inflammatory signaling.

التفاصيل البيبلوغرافية
العنوان: Gut microbiota modulation by jabuticaba peel and its effect on glucose metabolism via inflammatory signaling.
المؤلفون: Loubet Filho PS; Laboratory of Nutrition and Metabolism, School of Food Engineering, University of Campinas - UNICAMP, P.O. Box 6121, 13083-862, Campinas, SP, Brazil., Baseggio AM; Laboratory of Nutrition and Metabolism, School of Food Engineering, University of Campinas - UNICAMP, P.O. Box 6121, 13083-862, Campinas, SP, Brazil., Vuolo MM; Laboratory of Nutrition and Metabolism, School of Food Engineering, University of Campinas - UNICAMP, P.O. Box 6121, 13083-862, Campinas, SP, Brazil., Reguengo LM; Laboratory of Nutrition and Metabolism, School of Food Engineering, University of Campinas - UNICAMP, P.O. Box 6121, 13083-862, Campinas, SP, Brazil., Telles Biasoto AC; Brazilian Agricultural Research Corporation, Embrapa Tropical Semi-arid, 56302-970, Petrolina, PE, Brazil., Correa LC; Brazilian Agricultural Research Corporation, Embrapa Tropical Semi-arid, 56302-970, Petrolina, PE, Brazil., Junior SB; São Carlos Institute of Chemistry (IQSC), University of São Paulo (USP), São Carlos, SP, Brazil., Alves Cagnon VH; Department of Structural and Functional Biology, Institute of Biology, University of Campinas- UNICAMP, Bertrand Russel Av, Campinas, SP, Brazil., Betim Cazarin CB; Laboratory of Nutrition and Metabolism, School of Food Engineering, University of Campinas - UNICAMP, P.O. Box 6121, 13083-862, Campinas, SP, Brazil., Maróstica Júnior MR; Laboratory of Nutrition and Metabolism, School of Food Engineering, University of Campinas - UNICAMP, P.O. Box 6121, 13083-862, Campinas, SP, Brazil.
المصدر: Current research in food science [Curr Res Food Sci] 2022 Feb 10; Vol. 5, pp. 382-391. Date of Electronic Publication: 2022 Feb 10 (Print Publication: 2022).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101771059 Publication Model: eCollection Cited Medium: Internet ISSN: 2665-9271 (Electronic) Linking ISSN: 26659271 NLM ISO Abbreviation: Curr Res Food Sci Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: [Netherlands] : Elsevier B.V., [2019]-
مستخلص: Jabuticaba is a Brazilian berry known for its therapeutic potential against cancer, obesity, insulin resistance (IR), and others. It is a natural source of bioactive compounds, leading to better glucose metabolism, and attenuating obesity and IR through the reduction of pro-inflammatory status. The present study aimed to observe the prebiotic effect of freeze-dried jabuticaba peel (J) consumption on gut bacteria profile and describe its effects on IR derived from the lipopolysaccharides/Toll-like receptor-4 inflammatory pathway. Jabuticaba peel was chemically characterized, and its bioactive compounds were quantified. Twenty-four C57BL/6 mice were feed with a control diet (n = 6), control diet + J (n = 6), high-fat diet (HF) (n = 6), and HF + J (n = 6) for thirteen weeks. Gut bacteriota (16s RNA sequencing), glucose metabolism (fasting glucose and insulin, OGTT, ITT, HOMA-IR, and β, QUICKI), and inflammatory status (serum lipopolysaccharide, and protein expression) were assessed. The main bioactive compounds found in J were dietary fiber, and anthocyanins, and its consumption along with a healthy diet reduced the abundance of Firmicutes and Actinobacteriota phyla (p < 0.01), increased the Muribaculaceae and Lachnospiraceae families, and Faecalicatena genus (p < 0.05). The correlation test indicates a negative correlation between the Muribaculaceae and glucose metabolism. Jabuticaba peel is a nutritive source of bioactive compounds with prebiotic effects.
Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(© 2022 The Authors.)
References: J Nutr Biochem. 2019 Jan;63:101-108. (PMID: 30366260)
J Agric Food Chem. 2020 Feb 5;68(5):1315-1325. (PMID: 31913632)
Nat Commun. 2014 Apr 15;5:3654. (PMID: 24736369)
J Med Food. 2010 Apr;13(2):233-46. (PMID: 20170356)
J Sci Food Agric. 2016 Apr;96(6):1990-6. (PMID: 26084730)
Nat Rev Gastroenterol Hepatol. 2017 Aug;14(8):491-502. (PMID: 28611480)
Front Cell Infect Microbiol. 2019 Dec 03;9:409. (PMID: 31850241)
PLoS One. 2020 Jan 24;15(1):e0227886. (PMID: 31978162)
Front Microbiol. 2020 Aug 26;11:2032. (PMID: 32983031)
Nutrients. 2021 Jan 23;13(2):. (PMID: 33498671)
Can J Biochem Physiol. 1959 Aug;37(8):911-7. (PMID: 13671378)
J Mol Med (Berl). 2017 Jan;95(1):1-8. (PMID: 27900395)
Nature. 2006 Dec 21;444(7122):1027-31. (PMID: 17183312)
J Nutr. 1993 Nov;123(11):1939-51. (PMID: 8229312)
Nature. 2019 May;569(7758):641-648. (PMID: 31142853)
Food Chem. 2016 Nov 15;211:185-97. (PMID: 27283622)
Mol Nutr Food Res. 2017 Oct;61(10):. (PMID: 28544198)
Microorganisms. 2021 Jul 21;9(8):. (PMID: 34442633)
Nat Methods. 2016 Jul;13(7):581-3. (PMID: 27214047)
Food Res Int. 2015 Oct;76(Pt 3):796-803. (PMID: 28455065)
Food Funct. 2020 Feb 26;11(2):1547-1559. (PMID: 32003372)
Trends Endocrinol Metab. 2011 Apr;22(4):117-23. (PMID: 21353592)
PLoS One. 2014 Jan 22;9(1):e85423. (PMID: 24465556)
Microorganisms. 2020 Aug 14;8(8):. (PMID: 32824001)
Sci Rep. 2017 Mar 28;7:45308. (PMID: 28349946)
Nutr Rev. 2007 Oct;65(10):439-50. (PMID: 17972438)
J Biol Chem. 1957 May;226(1):497-509. (PMID: 13428781)
Nat Microbiol. 2017 Nov;2(11):1533-1542. (PMID: 28894102)
Br J Nutr. 2013 Aug 28;110(3):447-55. (PMID: 23415177)
Foods. 2019 Dec 05;8(12):. (PMID: 31817505)
Nutrients. 2018 Mar 30;10(4):. (PMID: 29601492)
Nutrients. 2020 May 19;12(5):. (PMID: 32438689)
J Agric Food Chem. 2015 Jul 15;63(27):6172-80. (PMID: 26066489)
Lab Anim. 2007 Jan;41(1):111-9. (PMID: 17234057)
J Obes Metab Syndr. 2017 Jun;26(2):86-96. (PMID: 31089501)
Food Chem. 2020 Mar 30;309:125735. (PMID: 31704077)
J Nutr. 2018 Feb 1;148(2):209-219. (PMID: 29490092)
J Nutr Biochem. 2017 Dec;50:16-25. (PMID: 28968517)
Biomed Chromatogr. 2006 Aug;20(8):674-82. (PMID: 16206138)
Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14691-6. (PMID: 20679230)
J Obes. 2016;2016:7353642. (PMID: 27703805)
Genome Res. 2009 Dec;19(12):2317-23. (PMID: 19819907)
J Clin Endocrinol Metab. 2000 Jul;85(7):2402-10. (PMID: 10902785)
Stat Appl Genet Mol Biol. 2004;3:Article3. (PMID: 16646809)
Diabetologia. 1985 Jul;28(7):412-9. (PMID: 3899825)
Sci Rep. 2019 Sep 9;9(1):12918. (PMID: 31501492)
Microbiome. 2019 Feb 19;7(1):28. (PMID: 30782206)
Science. 2001 Mar 23;291(5512):2316. (PMID: 11269298)
فهرسة مساهمة: Keywords: Berries; Bioactive compounds; Dysbiosis; Insulin resistance; Obesity; Prebiotics
تواريخ الأحداث: Date Created: 20220224 Latest Revision: 20220225
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC8850559
DOI: 10.1016/j.crfs.2022.02.001
PMID: 35198998
قاعدة البيانات: MEDLINE
الوصف
تدمد:2665-9271
DOI:10.1016/j.crfs.2022.02.001