دورية أكاديمية
أعرض في EDS

The Influenza Vaccine May Protect Pregnant and Postpartum Women against Severe COVID-19.

التفاصيل البيبلوغرافية
العنوان: The Influenza Vaccine May Protect Pregnant and Postpartum Women against Severe COVID-19.
المؤلفون: Paganoti CF; Division of Clinical Obstetrics, Hospital das Clinicas HCFMUSP, Faculty of Medicine, University of São Paulo, São Paulo 05403-000, Brazil., Rodrigues AS; Department of Statistics, Federal University of Espírito Santo, Vitória 29075-910, Brazil., Francisco RPV; Discipline of Obstetrics, Department of Obstetrics and Gynecology, Hospital das Clinicas HCFMUSP, Faculty of Medicine, University of São Paulo, São Paulo 05403-000, Brazil., Costa RAD; Division of Clinical Obstetrics, Hospital das Clinicas HCFMUSP, Faculty of Medicine, University of São Paulo, São Paulo 05403-000, Brazil.
المصدر: Vaccines [Vaccines (Basel)] 2022 Jan 28; Vol. 10 (2). Date of Electronic Publication: 2022 Jan 28.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101629355 Publication Model: Electronic Cited Medium: Print ISSN: 2076-393X (Print) Linking ISSN: 2076393X NLM ISO Abbreviation: Vaccines (Basel) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI AG
مستخلص: The SARS-CoV-2 pandemic has imposed a huge challenge on the antenatal care of pregnant women worldwide, with the maternal mortality rate being raised to alarming levels. While COVID-19 vaccines were developed, some studies highlighted a possible relationship between influenza vaccination and lower odds of COVID-19 infection. As obstetric patients belong to a high-risk group for respiratory diseases, this study evaluated whether influenza vaccination reduces the severity of COVID-19 infection and mortality among pregnant and postpartum women. We conducted a retrospective cohort study on 3370 pregnant and postpartum women from the Brazilian national database, where they were grouped according to their influenza vaccination status before the onset of COVID-19 symptoms. The intensive care unit admission and intubation rates were significantly higher among subjects in the unvaccinated group ( p = 0.002 and p < 0.001, respectively). The odds of mortality risk among those who received the vaccine was 0.33, with a 95% confidence interval of 0.23-0.47. The numbers of patients who needed to be vaccinated to avoid a case of intensive care unit admission, intubation, or death due to COVID-19 were 11, 15, and 11, respectively. Influenza vaccines could confer protection against severe COVID-19 infection in pregnant and postpartum women.
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معلومات مُعتمدة: INV-027961 United States GATES Bill & Melinda Gates Foundation; 445881/2020-8 National Council for Scientific and Technological Development; 007/2021 Fundação de Amparo à Pesquisa do Espírito Santo
فهرسة مساهمة: Keywords: COVID-19; influenza vaccines; maternal mortality; pregnancy
تواريخ الأحداث: Date Created: 20220226 Latest Revision: 20220301
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC8875780
DOI: 10.3390/vaccines10020206
PMID: 35214665
قاعدة البيانات: MEDLINE
الوصف
تدمد:2076-393X
DOI:10.3390/vaccines10020206