دورية أكاديمية
Prevalence of myocardial perfusion scintigraphy derived ischemia in coronary lesions with discordant fractional flow reserve and non-hyperemic pressure ratios.
| العنوان: | Prevalence of myocardial perfusion scintigraphy derived ischemia in coronary lesions with discordant fractional flow reserve and non-hyperemic pressure ratios. |
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| المؤلفون: | Higashioka D; Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan., Shiono Y; Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan. Electronic address: yshiono@wakayama-med.ac.jp., Emori H; Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan., Khalifa AKM; Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan., Takahata M; Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan., Wada T; Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan., Fujita S; Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan., Kashiwagi M; Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan., Shimamura K; Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan., Kuroi A; Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan., Tanimoto T; Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan., Kubo T; Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan., Akasaka T; Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan., Tanaka A; Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan. |
| المصدر: | International journal of cardiology [Int J Cardiol] 2022 Jun 15; Vol. 357, pp. 20-25. Date of Electronic Publication: 2022 Feb 24. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8200291 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1874-1754 (Electronic) Linking ISSN: 01675273 NLM ISO Abbreviation: Int J Cardiol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Amsterdam : Elsevier Original Publication: Amsterdam : Elsevier/North-Holland Biomedical Press, c1981- |
| مواضيع طبية MeSH: | Coronary Artery Disease*/diagnostic imaging , Coronary Artery Disease*/epidemiology , Coronary Stenosis* , Fractional Flow Reserve, Myocardial*/physiology , Hyperemia*, Cardiac Catheterization ; Coronary Angiography ; Coronary Vessels ; Humans ; Ischemia ; Perfusion Imaging ; Predictive Value of Tests ; Prevalence ; Severity of Illness Index ; Tomography, X-Ray Computed |
| مستخلص: | Background: Whether a coronary lesion with discordant fractional flow reserve (FFR) and non-hyperemic pressure ratios (NHPRs) causes myocardial ischemia remains unclear. This study investigates the prevalence of myocardial ischemia as assessed by myocardial perfusion scintigraphy (MPS) in coronary lesions with discordant FFR and instantaneous wave-free ratio (iFR), and, additionally, other NHPRs: resting full-cycle ratio (RFR), diastolic pressure ratio (dPR), and resting Pd/Pa. Methods: A total of 484 coronary arteries in 295 patients with stable coronary artery disease that underwent MPS and invasive physiological pressure measurements were categorized into four groups (FFR+/NHPR+, FFR+/NHPR-, FFR-/NHPR+, and FFR-/NHPR-) using the respective cut-off values of FFR ≤ 0.80, iFR ≤ 0.89, RFR ≤ 0.89, dPR < 0.89, and Pd/Pa ≤ 0.92. The proportions of MPS-derived myocardial ischemia in a relevant myocardial territory were compared between the four groups. Results: In total, 175 (36%), 61(13%), 35(7%) and 213(44%) vessels were classified into FFR+/iFR+, FFR+/iFR-, FFR-/iFR+ and FFR-/iFR- groups, respectively. The FFR+/iFR+ group had the highest proportion of MPS-derived ischemia (70%), followed by the FFR+/iFR- group (38%), the FFR-/iFR+ group (23%), and the FFR-/iFR- group (10%) (P < 0.001). Similar proportions of MPS-derived ischemia were found when RFR. (70%, 34%, 24%, and 10%, P < 0.001), dPR (70%, 38%, 26%, and 10%, P < 0.001), and Pd/Pa (70%, 31%, 22%, and 10%, P < 0.001) were used in place of iFR. Conclusions: The prevalence of MPS-derived myocardial ischemia in coronary lesions with discordance between FFR and NHPRs is lower than those with concordantly positive FFR and NHPRs, but higher than those with concordantly negative FFR and NHPRs. (Copyright © 2022 Elsevier B.V. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Fractional flow reserve; Instantaneous wave-free ratio; Myocardial perfusion scintigraphy; Non-hyperemic pressure ratio |
| تواريخ الأحداث: | Date Created: 20220227 Date Completed: 20220503 Latest Revision: 20220505 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1016/j.ijcard.2022.02.031 |
| PMID: | 35219745 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1874-1754 |
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| DOI: | 10.1016/j.ijcard.2022.02.031 |