دورية أكاديمية
Wildlife in Cameroon harbor diverse coronaviruses, including many closely related to human coronavirus 229E.
| العنوان: | Wildlife in Cameroon harbor diverse coronaviruses, including many closely related to human coronavirus 229E. |
|---|---|
| المؤلفون: | Ntumvi NF; Metabiota Cameroon Ltd, Yaoundé, Centre Region Avenue Mvog-Fouda Ada, Av 1.085, Carrefour Intendance, Yaoundé, BP 15939, Cameroon., Ndze VN, Gillis A; Metabiota Inc, 425 California Street, Suite 1200, San Francisco, CA 94104, USA., Le Doux Diffo J; Metabiota Cameroon Ltd, Yaoundé, Centre Region Avenue Mvog-Fouda Ada, Av 1.085, Carrefour Intendance, Yaoundé, BP 15939, Cameroon., Tamoufe U; Metabiota Cameroon Ltd, Yaoundé, Centre Region Avenue Mvog-Fouda Ada, Av 1.085, Carrefour Intendance, Yaoundé, BP 15939, Cameroon., Takuo JM; Metabiota Cameroon Ltd, Yaoundé, Centre Region Avenue Mvog-Fouda Ada, Av 1.085, Carrefour Intendance, Yaoundé, BP 15939, Cameroon., Mouiche MMM; Mosaic, Yaoundé, Centre Region, BP 35353, Cameroon., Nwobegahay J; CRESAR, Yaoundé, Centre Region 7039 Carrefour Intendance, BP 15939, Cameroon., LeBreton M, Rimoin AW; Department of Epidemiology, University of California, 71-254 Center for Health Sciences, 650 Charles E. Young Drive South, Los Angeles, CA 90095, USA., Schneider BS; Metabiota Inc, 425 California Street, Suite 1200, San Francisco, CA 94104, USA., Monagin C, McIver DJ; Metabiota Inc, 7-1611 Bowen Road, Nanaimo BC V9S 1G5, Canada., Roy S; Labyrinth Global Health, 546 15TH Ave NE, St.Petersburg, FL 33704, USA., Ayukekbong JA; Metabiota Inc, 7-1611 Bowen Road, Nanaimo BC V9S 1G5, Canada., Saylors KE; Labyrinth Global Health, 546 15TH Ave NE, St.Petersburg, FL 33704, USA., Joly DO; Metabiota Inc, 7-1611 Bowen Road, Nanaimo BC V9S 1G5, Canada., Wolfe ND, Rubin EM; Metabiota Inc, 425 California Street, Suite 1200, San Francisco, CA 94104, USA., Lange CE; Metabiota Inc, 7-1611 Bowen Road, Nanaimo BC V9S 1G5, Canada. |
| المصدر: | Virus evolution [Virus Evol] 2022 Jan 12; Vol. 8 (1), pp. veab110. Date of Electronic Publication: 2022 Jan 12 (Print Publication: 2022). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Oxford University Press Country of Publication: England NLM ID: 101664675 Publication Model: eCollection Cited Medium: Print ISSN: 2057-1577 (Print) Linking ISSN: 20571577 NLM ISO Abbreviation: Virus Evol Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Oxford : Oxford University Press, [2015]- |
| مستخلص: | Zoonotic spillover of animal viruses into human populations is a continuous and increasing public health risk. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) highlights the global impact of emergence. Considering the history and diversity of coronaviruses (CoVs), especially in bats, SARS-CoV-2 will likely not be the last to spillover from animals into human populations. We sampled and tested wildlife in the Central African country Cameroon to determine which CoVs are circulating and how they relate to previously detected human and animal CoVs. We collected animal and ecological data at sampling locations and used family-level consensus PCR combined with amplicon sequencing for virus detection. Between 2003 and 2018, samples were collected from 6,580 animals of several different orders. CoV RNA was detected in 175 bats, a civet, and a shrew. The CoV RNAs detected in the bats represented 17 different genetic clusters, coinciding with alpha ( n = 8) and beta ( n = 9) CoVs. Sequences resembling human CoV-229E (HCoV-229E) were found in 40 Hipposideridae bats. Phylogenetic analyses place the human-derived HCoV-229E isolates closest to those from camels in terms of the S and N genes but closest to isolates from bats for the envelope, membrane, and RNA-dependent RNA polymerase genes. The CoV RNA positivity rate in bats varied significantly (P < 0.001) between the wet (8.2 per cent) and dry seasons (4.5 per cent). Most sampled species accordingly had a wet season high and dry season low, while for some the opposite was found. Eight of the suspected CoV species of which we detected RNA appear to be entirely novel CoV species, which suggests that CoV diversity in African wildlife is still rather poorly understood. The detection of multiple different variants of HCoV-229E-like viruses supports the bat reservoir hypothesis for this virus, with the phylogenetic results casting some doubt on camels as an intermediate host. The findings also support the previously proposed influence of ecological factors on CoV circulation, indicating a high level of underlying complexity to the viral ecology. These results indicate the importance of investing in surveillance activities among wild animals to detect all potential threats as well as sentinel surveillance among exposed humans to determine emerging threats. (© The Author(s) 2021. Published by Oxford University Press.) |
| References: | Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):9864-9. (PMID: 27528677) Microbes Infect. 2019 Jan - Feb;21(1):10-19. (PMID: 29913297) PLoS One. 2014 Jun 24;9(6):e100172. (PMID: 24959855) Virus Evol. 2017 Jun 12;3(1):vex012. (PMID: 28630747) Proc Natl Acad Sci U S A. 2021 Apr 13;118(15):. (PMID: 33822740) Syst Biol. 2012 May;61(3):539-42. (PMID: 22357727) J Virol. 2005 Sep;79(18):11892-900. (PMID: 16140765) Curr Top Microbiol Immunol. 2003;278:47-71. (PMID: 12934941) One Health Outlook. 2020 Feb 7;2:2. (PMID: 33824945) Clin Microbiol Infect. 2016 Nov;22(11):911-915. (PMID: 27615720) Microbiol Mol Biol Rev. 2008 Sep;72(3):457-70. (PMID: 18772285) Ecohealth. 2020 Mar;17(1):152-159. (PMID: 31811597) Nature. 2020 Mar;579(7798):270-273. (PMID: 32015507) Virus Res. 2012 Jul;167(1):67-73. (PMID: 22561208) Ann N Y Acad Sci. 2017 Feb;1389(1):124-146. (PMID: 28036113) Nature. 2008 Feb 21;451(7181):990-3. (PMID: 18288193) Arch Virol. 2020 Aug;165(8):1869-1875. (PMID: 32488616) Emerg Infect Dis. 2010 Aug;16(8):1217-23. (PMID: 20678314) Ecohealth. 2020 Sep;17(3):292-301. (PMID: 33175278) PLoS One. 2018 Mar 26;13(3):e0194527. (PMID: 29579103) PLoS Comput Biol. 2019 Apr 8;15(4):e1006650. (PMID: 30958812) Emerg Infect Dis. 2014 May;20(5):741-5. (PMID: 24750692) Trop Med Infect Dis. 2019 Jul 02;4(3):. (PMID: 31269631) J Virol. 2012 Dec;86(23):12816-25. (PMID: 22993147) Infect Genet Evol. 2018 Mar;58:279-289. (PMID: 29355607) N Engl J Med. 2012 Nov 8;367(19):1814-20. (PMID: 23075143) Soc Sci Med. 2021 Jan;268:113358. (PMID: 32992090) PLoS Pathog. 2017 Nov 30;13(11):e1006698. (PMID: 29190287) Adv Virus Res. 2018;100:163-188. (PMID: 29551135) Nat Rev Microbiol. 2020 Aug;18(8):461-471. (PMID: 32528128) N Engl J Med. 2003 May 15;348(20):1967-76. (PMID: 12690091) J Virol. 2014 Oct;88(19):11297-303. (PMID: 25031349) J Virol. 2017 Feb 14;91(5):. (PMID: 28077633) Emerg Infect Dis. 2005 Dec;11(12):1822-7. (PMID: 16485465) Infect Genet Evol. 2009 Dec;9(6):1185-96. (PMID: 19800030) Sci Rep. 2015 Oct 07;5:14830. (PMID: 26445169) Science. 2016 Jan 1;351(6268):81-4. (PMID: 26678874) Nature. 2020 Jul;583(7815):282-285. (PMID: 32218527) J Virol. 2010 Nov;84(21):11336-49. (PMID: 20686038) Curr Biol. 2020 Apr 6;30(7):1346-1351.e2. (PMID: 32197085) mBio. 2010 Oct 12;1(4):. (PMID: 21063474) Yale J Biol Med. 1982 May-Aug;55(3-4):271-5. (PMID: 6758373) J R Soc Interface. 2014 Dec 6;11(101):20140950. (PMID: 25401184) Emerg Infect Dis. 2013 Mar;19(3):456-9. (PMID: 23622767) Microb Genom. 2021 Apr;7(4):. (PMID: 33871330) Cold Spring Harb Perspect Med. 2011 Sep;1(1):a006841. (PMID: 22229120) J Virol. 2015 Dec;89(23):11858-70. (PMID: 26378164) Clin Microbiol Rev. 2009 Jan;22(1):127-45, Table of Contents. (PMID: 19136437) Clin Infect Dis. 2010 Jun 15;50(12):1636-40. (PMID: 20450416) PLoS One. 2017 Sep 13;12(9):e0184718. (PMID: 28902913) Emerg Infect Dis. 2009 Mar;15(3):482-5. (PMID: 19239771) J Virol. 2021 Oct 27;95(22):e0117321. (PMID: 34431700) Vector Borne Zoonotic Dis. 2013 Jul;13(7):516-9. (PMID: 23473214) Nat Rev Microbiol. 2019 Mar;17(3):181-192. (PMID: 30531947) Proc Natl Acad Sci U S A. 2005 Sep 27;102(39):14040-5. (PMID: 16169905) J Gen Virol. 2010 Apr;91(Pt 4):1058-62. (PMID: 20016037) Exp Biol Med (Maywood). 2009 Oct;234(10):1117-27. (PMID: 19546349) Infect Genet Evol. 2020 Apr;79:104212. (PMID: 32004758) Virol J. 2015 Mar 12;12:42. (PMID: 25888853) Viruses. 2021 May 18;13(5):. (PMID: 34070175) Emerg Infect Dis. 2009 Sep;15(9):1377-84. (PMID: 19788804) Nature. 2007 May 17;447(7142):279-83. (PMID: 17507975) PLoS One. 2021 Jun 9;16(6):e0236971. (PMID: 34106949) Sci Rep. 2020 Apr 30;10(1):7314. (PMID: 32355260) J Mammal. 1974 May;55(2):453-4. (PMID: 4833188) Science. 2005 Oct 28;310(5748):676-9. (PMID: 16195424) Nat Commun. 2017 Oct 24;8(1):1124. (PMID: 29066781) Trends Microbiol. 2017 Jan;25(1):35-48. (PMID: 27743750) PLoS Negl Trop Dis. 2019 Jun 13;13(6):e0007428. (PMID: 31194734) |
| معلومات مُعتمدة: | DP1 OD000370 United States OD NIH HHS; K01 TW000003 United States TW FIC NIH HHS |
| فهرسة مساهمة: | Keywords: Coronavirus; HCoV-229E; bats; cameroon; seasonality; wildlife |
| تواريخ الأحداث: | Date Created: 20220302 Latest Revision: 20240512 |
| رمز التحديث: | 20240512 |
| مُعرف محوري في PubMed: | PMC8867583 |
| DOI: | 10.1093/ve/veab110 |
| PMID: | 35233291 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder كن أول من يترك تعليقا!