دورية أكاديمية
أعرض في EDS

Evaluation of family planning methods in married women with epilepsy.

التفاصيل البيبلوغرافية
العنوان: Evaluation of family planning methods in married women with epilepsy.
المؤلفون: Ershadi F; Medical Student, Birjand University of Medical Sciences, Birjand, Iran., Mousavi Mirzaei SM; Department of Neurology, School of Medicine, Birjand University of Medical Sciences, Birjand, Iran., Tabrizi N; Department of Neurology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran., Roshanravan B; Student Research Committee, Birjand University of Medical Sciences, Birjand, Iran., Sahebnasagh A; Clinical Research Center, Department of Internal Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran., Avan R; Department of Clinical Pharmacy, School of Pharmacy, Medical Toxicology and Drug Abuse Research Center, Birjand University of Medical Sciences, Birjand, Iran. Electronic address: avanr91@gmail.com.
المصدر: Epilepsy & behavior : E&B [Epilepsy Behav] 2022 Apr; Vol. 129, pp. 108618. Date of Electronic Publication: 2022 Mar 04.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 100892858 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-5069 (Electronic) Linking ISSN: 15255050 NLM ISO Abbreviation: Epilepsy Behav Subsets: MEDLINE
أسماء مطبوعة: Original Publication: San Diego, CA : Academic Press, c2000-
مواضيع طبية MeSH: Epilepsy*/chemically induced , Epilepsy*/drug therapy , Epilepsy*/epidemiology , Pregnancy Complications*/drug therapy, Adult ; Anticonvulsants/therapeutic use ; Family Planning Services ; Female ; Humans ; Lamotrigine/therapeutic use ; Levetiracetam/therapeutic use ; Pregnancy ; Young Adult
مستخلص: Background: Epilepsy is one of the most common neurologic unit diseases that have different prevalence in different parts of the world. Antiepileptic drugs (AEDs) are associated with major fertility risks for women of childbearing age. Due to the fact that studies on family planning methods in married women with epilepsy (WWE) have not been conducted in Iran, the aim of this study was to evaluate the family planning methods in married WWE in Birjand, Iran.
Methods: An analytical-descriptive study was performed on 126 married WWE hospitalized in the neurology ward or referred to Vali-e-Asr specialized and sub-specialized clinic in Birjand. Demographic information of patients as well as data on the type of used AED, and various methods of family planning were collected in a questionnaire. Data analysis was performed using Chi-square and Fisher tests. All of the above analyses were considered at a significance level of less than 5% by SPSS v.19 software.
Results: The mean age of the patients was 33.41 ± 9.15 years. The mean age of experiencing the first seizure and the onset of menstruation were 24.82 and 13.79 years, respectively. Fifty (35.5%), 38 (27%), 15 (10.6%), 14 (9.9%), and 14 (9.9%) patients used sodium valproate, carbamazepine, phenytoin, levetiracetam, and lamotrigine, respectively. The results showed that 72 sexually active patients (70.6%) used family planning methods, of which 43 patients (59.7%) used withdrawal method, 20 patients (27.8%) used condoms, and 6 patients (8.3%) used oral contraceptive pills (OCP). Eight patients (9.6%) had a history of unintended pregnancy and 3 patients (3.6%) had a history of abortion.
Conclusion: It is recommended to apply effective family planning methods in married WWE to prevent unintended pregnancies and the subsequent adverse effects in the fetus, considering the fact that a significant percentage of WWE did not use effective family planning methods and 8 cases of unintended pregnancies were reported. Because of high consumption of valproate in women of childbearing age in our study and concerning issue about its fetal malformation, it is recommended to reduce the administration of valproate in this population. Moreover, regarding the low consumption of folic acid, especially for women of childbearing age and pregnant WWE who are taking AED, the necessary recommendations should be made by our physicians.
(Copyright © 2022 Elsevier Inc. All rights reserved.)
فهرسة مساهمة: Keywords: Antiepileptic drugs; Epilepsy; Family planning methods; Fetal abnormality; Seizure
المشرفين على المادة: 0 (Anticonvulsants)
44YRR34555 (Levetiracetam)
U3H27498KS (Lamotrigine)
تواريخ الأحداث: Date Created: 20220308 Date Completed: 20220405 Latest Revision: 20220512
رمز التحديث: 20240628
DOI: 10.1016/j.yebeh.2022.108618
PMID: 35257991
قاعدة البيانات: MEDLINE
الوصف
تدمد:1525-5069
DOI:10.1016/j.yebeh.2022.108618