دورية أكاديمية

BMI, sex and outcomes in hospitalised patients in western Sweden during the COVID-19 pandemic.

التفاصيل البيبلوغرافية
العنوان: BMI, sex and outcomes in hospitalised patients in western Sweden during the COVID-19 pandemic.
المؤلفون: Lindgren M; Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Medicine Geriatrics and Emergency Medicine, Sahlgrenska University Hospital, Östra Hospital, Region Västra Götaland, Smörslottsgatan 1, 416 85, Gothenburg, Sweden., Toska T; Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Medicine Geriatrics and Emergency Medicine, Sahlgrenska University Hospital, Östra Hospital, Region Västra Götaland, Smörslottsgatan 1, 416 85, Gothenburg, Sweden., Alex C; Department of Medicine Geriatrics and Emergency Medicine, Sahlgrenska University Hospital, Östra Hospital, Region Västra Götaland, Smörslottsgatan 1, 416 85, Gothenburg, Sweden., Lundberg CE; Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Cronie O; School of Public Health and Community Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden., Rosengren A; Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Medicine Geriatrics and Emergency Medicine, Sahlgrenska University Hospital, Östra Hospital, Region Västra Götaland, Smörslottsgatan 1, 416 85, Gothenburg, Sweden., Adiels M; School of Public Health and Community Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden., Sjöland H; Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. helen.sjoland@vgregion.se.; Department of Medicine Geriatrics and Emergency Medicine, Sahlgrenska University Hospital, Östra Hospital, Region Västra Götaland, Smörslottsgatan 1, 416 85, Gothenburg, Sweden. helen.sjoland@vgregion.se.
المصدر: Scientific reports [Sci Rep] 2022 Mar 22; Vol. 12 (1), pp. 4918. Date of Electronic Publication: 2022 Mar 22.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : Nature Publishing Group, copyright 2011-
مواضيع طبية MeSH: COVID-19*/epidemiology, Body Mass Index ; Female ; Humans ; Male ; Pandemics ; Sweden/epidemiology ; Thinness/complications
مستخلص: High body mass index (BMI) is associated with severe COVID-19 but findings regarding the need of intensive care (IC) and mortality are mixed. Using electronic health records, we identified all patients in western Sweden hospitalised with COVID-19 to evaluate 30-day mortality or assignment to IC. Adjusted logistic regression models were used to estimate odds ratios (OR) and 95% confidence intervals (CI) for outcomes. Of totally 9761 patients, BMI was available in 7325 (75%), included in the study. There was a marked inverse association between BMI and age (underweight and normal weight patients were on average 78 and 75 years, whereas overweight and obese were 68 and 62 years). While older age, male sex and several comorbidities associated with higher mortality after multivariable adjustment, BMI did not. However, BMI ≥ 30 kg/m 2 (OR 1.46, 95% CI 1.21-1.75) was associated with need of IC; this association was restricted to women (BMI ≥ 30; OR 1.96 (95% CI 1.41-2.73), and not significant in men; OR 1.22 (95% CI 0.97-1.54). In this comprehensive hospital population with COVID-19, BMI was not associated with 30-day mortality risk. Among the obese, women, but not men, had a higher risk of assignment to IC.
(© 2022. The Author(s).)
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معلومات مُعتمدة: 2018-02527 Vetenskapsrådet,Sweden; VRREG 2019-00193 Vetenskapsrådet,Sweden; 2020-05792 Vetenskapsrådet,Sweden
تواريخ الأحداث: Date Created: 20220323 Date Completed: 20220404 Latest Revision: 20220405
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC8939489
DOI: 10.1038/s41598-022-09027-w
PMID: 35318438
قاعدة البيانات: MEDLINE