دورية أكاديمية
أعرض في EDS

Association Between Type 1 Diabetes Mellitus and Celiac Disease: Autoimmune Disorders With a Shared Genetic Background.

التفاصيل البيبلوغرافية
العنوان: Association Between Type 1 Diabetes Mellitus and Celiac Disease: Autoimmune Disorders With a Shared Genetic Background.
المؤلفون: Flores Monar GV; Research, Universidad Central del Ecuador, Quito, ECU., Islam H; Research, Faisalabad Medical University, Faisalabad, PAK., Puttagunta SM; Research, Dr. Pinnamaneni Siddhartha Institute Medical College, Chinoutpalli, IND., Islam R; Research, Faisalabad Medical University, Faisalabad, PAK., Kundu S; Research, Radha Gobinda Kar (R.G. Kar) Medical College, Kolkata, IND., Jha SB; Research, Jinan University School of Medicine, Guangzhou, CHN., Rivera AP; Research, Universidad Americana (UAM) Facultad de Medicina, Managua, NIC., Sange I; Research, K.J. Somaiya Medical College, Hospital and Research Center, Mumbai, IND.
المصدر: Cureus [Cureus] 2022 Mar 07; Vol. 14 (3), pp. e22912. Date of Electronic Publication: 2022 Mar 07 (Print Publication: 2022).
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Cureus, Inc Country of Publication: United States NLM ID: 101596737 Publication Model: eCollection Cited Medium: Print ISSN: 2168-8184 (Print) Linking ISSN: 21688184 NLM ISO Abbreviation: Cureus Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Palo Alto, CA : Cureus, Inc.
مستخلص: Type 1 diabetes mellitus (T1DM) and celiac disease (CD) are one of the most recognized related autoimmune disorders as they share a common genetic background that has been found in the HLA genotype, more specifically DQ2 and DQ8 molecules. Studies have shown that environmental factors as early or late exposure to cereals in the first months of life or the acquired viral infections have been implicated in the risk of development of autoantigens. CD, in most cases, is asymptomatic; therefore, it goes underdiagnosed. As a result, it has been linked to late consequences as decreased growth, delayed puberty, and anemia. Also, CD has been considered an independent risk factor for nephropathy and retinopathy. Therefore, in T1DM patients, as high-risk individuals, a CD screening has been recommended, especially to analyze their joint management. A gluten-free diet has been studied and linked to possible benefits in glycemic control or decreasing the hypoglycemic episodes in T1DM and preventing in CD the late bowel mucosal damage as gluten has been well documented as the primary trigger of these autoimmune responses. This article has reviewed the concurrent occurrence of T1DM and CD regarding the pathogenesis, clinical overlaps, screening, and management options.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2022, Flores Monar et al.)
References: JAMA. 2013 Jun 19;309(23):2473-9. (PMID: 23780460)
Ann Intern Med. 2020 Jan 7;172(1):ITC1-ITC16. (PMID: 31905394)
Am J Gastroenterol. 2013 May;108(5):656-76; quiz 677. (PMID: 23609613)
Diabetes Res Clin Pract. 2017 Jun;128:40-50. (PMID: 28437734)
Diabetes Care. 2003 Jun;26(6):1932-9. (PMID: 12766138)
Lancet. 1969 May 17;1(7603):1021. (PMID: 4181178)
Pediatrics. 2014 Apr;133(4):e938-45. (PMID: 24685959)
Clin Chem. 2011 Feb;57(2):176-85. (PMID: 21205883)
BMJ Open. 2015 Nov 02;5(11):e009088. (PMID: 26525723)
BMJ Open. 2015 May 11;5(5):e008097. (PMID: 25968008)
BMJ. 2018 Jan 3;360:j5295. (PMID: 29298776)
World J Clin Pediatr. 2021 Jul 9;10(4):53-71. (PMID: 34316439)
JAMA. 2003 Oct 1;290(13):1713-20. (PMID: 14519705)
J Clin Res Pediatr Endocrinol. 2020 Aug 21;13(1):72-79. (PMID: 32820875)
Diabetes. 2016 Jun;65(6):1690-8. (PMID: 26953162)
Endocrinol Metab Clin North Am. 2010 Sep;39(3):481-97. (PMID: 20723815)
JAMA Pediatr. 2013 Sep;167(9):808-15. (PMID: 23836309)
BMJ. 2004 Mar 27;328(7442):750-4. (PMID: 15044291)
Pediatr Diabetes. 2018 Dec;19(8):1422-1428. (PMID: 30209881)
Diabetes Care. 2014;37(1):39-43. (PMID: 24356596)
Diabetes Care. 2015 May;38(5):801-7. (PMID: 25690004)
Lancet Diabetes Endocrinol. 2020 Mar;8(3):226-238. (PMID: 31999944)
Diabetes Care. 2018 Jan;41(Suppl 1):S28-S37. (PMID: 29222374)
Diabet Med. 2006 Aug;23(8):857-66. (PMID: 16911623)
Diabetologia. 2019 Mar;62(3):408-417. (PMID: 30483858)
Pediatr Diabetes. 2014 Sep;15 Suppl 20:18-25. (PMID: 25325095)
Ann Afr Med. 2021 Jan-Mar;20(1):19-23. (PMID: 33727507)
Diabetes Res Clin Pract. 2004 Dec;66 Suppl 1:S27-32. (PMID: 15563975)
Pediatr Diabetes. 2011 Jun;12(4 Pt 1):322-5. (PMID: 21615651)
Crit Rev Clin Lab Sci. 2010 Mar-Apr;47(2):51-71. (PMID: 20545565)
Lancet. 2016 Jun 4;387(10035):2331-2339. (PMID: 27302272)
Medicine (Baltimore). 2021 Mar 19;100(11):e24954. (PMID: 33725967)
Cells. 2019 Jul 19;8(7):. (PMID: 31331105)
Acta Diabetol. 2021 May;58(5):623-631. (PMID: 33483854)
Endocr Pract. 2020 Jun 2;26(6):660-667. (PMID: 32160043)
N Engl J Med. 2008 Dec 25;359(26):2849-50. (PMID: 19109586)
Acta Paediatr. 2017 Apr;106(4):639-646. (PMID: 27935157)
Pediatrics. 2015 Jul;136(1):e170-6. (PMID: 26077482)
Diabetes Care. 2017 Aug;40(8):1034-1040. (PMID: 28546222)
J Pediatr Gastroenterol Nutr. 2018 Apr;66(4):641-644. (PMID: 28957985)
Indian J Med Res. 2017 Mar;145(3):334-338. (PMID: 28749395)
Am J Gastroenterol. 2012 Oct;107(10):1538-44; quiz 1537, 1545. (PMID: 22850429)
J Intern Med. 2011 Jun;269(6):591-603. (PMID: 21401738)
Diabetes Care. 2015 Oct;38 Suppl 2:S37-44. (PMID: 26405070)
J Autoimmun. 2015 Nov;64:101-12. (PMID: 26272854)
Am J Clin Nutr. 2002 May;75(5):914-21. (PMID: 11976167)
Diabetologia. 2017 Oct;60(10):1931-1940. (PMID: 28770319)
Dig Dis. 2018;36(6):399-408. (PMID: 30045024)
فهرسة مساهمة: Keywords: celiac disease; gluten; hla; tissue-transglutaminase antibodies; type 1 diabetes mellitus
تواريخ الأحداث: Date Created: 20220411 Latest Revision: 20220413
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC8986520
DOI: 10.7759/cureus.22912
PMID: 35399440
قاعدة البيانات: MEDLINE
الوصف
تدمد:2168-8184
DOI:10.7759/cureus.22912