دورية أكاديمية
More than Drug Fever: Dexmedetomidine-Induced Hyperthermia in a Critically Ill Patient.
| العنوان: | More than Drug Fever: Dexmedetomidine-Induced Hyperthermia in a Critically Ill Patient. |
|---|---|
| المؤلفون: | Kressin CL; Acute Care Pharmacy Services, University of Kentucky HealthCare, Lexington, KY, USA., Bensadoun E; Pulmonary Critical Care and Sleep Medicine, University of Kentucky HealthCare, Lexington, KY, USA., James W; Pulmonary Critical Care and Sleep Medicine, University of Kentucky HealthCare, Lexington, KY, USA., Lawless B; Pulmonary Critical Care and Sleep Medicine, University of Kentucky HealthCare, Lexington, KY, USA., Kellum B; Pulmonary Critical Care and Sleep Medicine, University of Kentucky HealthCare, Lexington, KY, USA., Flannery AH; Acute Care Pharmacy Services, University of Kentucky HealthCare, Lexington, KY, USA.; Department of Pharmacy Practice and Science, University of Kentucky College of Pharmacy, Lexington, KY, USA. |
| المصدر: | Journal of pharmacy practice [J Pharm Pract] 2023 Aug; Vol. 36 (4), pp. 1026-1029. Date of Electronic Publication: 2022 Apr 14. |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Sage Publications Country of Publication: United States NLM ID: 8900945 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-1937 (Electronic) Linking ISSN: 08971900 NLM ISO Abbreviation: J Pharm Pract Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2002-> : Thousand Oaks, Calif. : Sage Publications Original Publication: [Philadelphia, PA] : W.B. Saunders, [1988]- |
| مواضيع طبية MeSH: | Dexmedetomidine*/adverse effects , Obesity, Morbid*/drug therapy , Hyperthermia, Induced*, Humans ; Female ; Hypnotics and Sedatives/adverse effects ; Critical Illness/therapy ; Drug Fever |
| مستخلص: | Dexmedetomidine is a selective alpha-2 adrenergic agonist utilized for sedation in critically ill patients. 1 We present the case of a morbidly obese critically ill patient who experienced profound hyperthermia, with a maximum temperature of 41.4°C, hours after starting a dexmedetomidine infusion that was otherwise not explained by her clinical diagnoses. The hyperthermia resolved hours following cessation of the infusion. Dexmedetomidine was assessed as probable in terms of causing this adverse effect. Dexmedetomidine may be associated not only with low-grade fever, but as demonstrated in our case, it may be associated with significant temperature elevations requiring cessation of therapy to restore normothermia. |
| References: | J Clin Pharmacol. 2021 Jul;61(7):848-856. (PMID: 33554338) Clin Pharmacol Ther. 1981 Aug;30(2):239-45. (PMID: 7249508) Chest. 2000 Jan;117(1):39-42. (PMID: 10631196) Crit Care Med. 2021 Jul 1;49(7):1205-1207. (PMID: 34135280) JAMA. 2009 Feb 4;301(5):489-99. (PMID: 19188334) J Pharm Pract. 2022 Oct;35(5):716-721. (PMID: 33813941) Anesth Analg. 2017 Dec;125(6):1898-1906. (PMID: 28763361) JAMA. 2012 Mar 21;307(11):1151-60. (PMID: 22436955) Anaesth Intensive Care. 2017 Nov;45(6):727-736. (PMID: 29137584) N Engl J Med. 2021 Apr 15;384(15):1424-1436. (PMID: 33528922) Crit Care Med. 2021 Jul 1;49(7):1118-1128. (PMID: 33729724) |
| معلومات مُعتمدة: | K23 DK128562 United States DK NIDDK NIH HHS |
| فهرسة مساهمة: | Keywords: critical care |
| المشرفين على المادة: | 67VB76HONO (Dexmedetomidine) 0 (Hypnotics and Sedatives) |
| تواريخ الأحداث: | Date Created: 20220414 Date Completed: 20230717 Latest Revision: 20240802 |
| رمز التحديث: | 20240802 |
| مُعرف محوري في PubMed: | PMC9724710 |
| DOI: | 10.1177/08971900221087948 |
| PMID: | 35421323 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1531-1937 |
|---|---|
| DOI: | 10.1177/08971900221087948 |