دورية أكاديمية
Invasive Group A Streptococcus Outbreaks Associated with Home Healthcare, England, 2018-2019.
| العنوان: | Invasive Group A Streptococcus Outbreaks Associated with Home Healthcare, England, 2018-2019. |
|---|---|
| المؤلفون: | Nabarro LE, Brown CS, Balasegaram S, Decraene V, Elston J, Kapadia S, Harrington P, Hoffman P, Mearkle R, Patel B, Ready D, Robinson E, Lamagni T |
| المصدر: | Emerging infectious diseases [Emerg Infect Dis] 2022 May; Vol. 28 (5). |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC) Country of Publication: United States NLM ID: 9508155 Publication Model: Print Cited Medium: Internet ISSN: 1080-6059 (Electronic) Linking ISSN: 10806040 NLM ISO Abbreviation: Emerg Infect Dis Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Atlanta, GA : National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC), [1995- |
| مواضيع طبية MeSH: | Cross Infection*/epidemiology , Streptococcal Infections*, Delivery of Health Care ; Disease Outbreaks/prevention & control ; England/epidemiology ; Humans ; Streptococcus pyogenes/genetics |
| مستخلص: | Healthcare-associated invasive group A Streptococcus (iGAS) outbreaks are common worldwide, but only England has reported outbreaks associated with home healthcare (HHC). We describe 10 outbreaks during 2018-2019 in England. A total of 96 iGAS cases (range 2-39 per outbreak) and 28 deaths (case-fatality rate 29%) occurred. Outbreak duration ranged from 3-517 days; median time between sequential cases was 20.5 days (range 1-225 days). Outbreak identification was difficult, but emm typing and whole-genome sequencing improved detection. Network analyses indicated multiple potential transmission routes. Screening of 366 HHC workers from 9 outbreaks identified group A Streptococcus carriage in just 1 worker. Outbreak control required multiple interventions, including improved infection control, equipment decontamination, and antimicrobial prophylaxis for staff. Transmission routes and effective interventions are not yet clear, and iGAS outbreaks likely are underrecognized. To improve patient safety and reduce deaths, public health agencies should be aware of HHC-associated iGAS. |
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| فهرسة مساهمة: | Keywords: Bacteria; England; Group A Streptococcus; Streptococci; Streptococcus pyogenes; disease outbreaks; infection control; long-term care; public health; whole-genome sequencing; wound infection |
| تواريخ الأحداث: | Date Created: 20220422 Date Completed: 20220425 Latest Revision: 20220508 |
| رمز التحديث: | 20221213 |
| مُعرف محوري في PubMed: | PMC9045425 |
| DOI: | 10.3201/eid2805.211497 |
| PMID: | 35451366 |
| قاعدة البيانات: | MEDLINE |
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