دورية أكاديمية
Assessment of repeated reference measurements to inform the validity of optical breast spectroscopy.
| العنوان: | Assessment of repeated reference measurements to inform the validity of optical breast spectroscopy. |
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| المؤلفون: | Lloyd R; Genetic Epidemiology Group, School of Population and Global Health, The University of Western Australia, 35 Stirling Highway M431, Crawley, Western Australia 6009, Australia., Walter J; University Health Network, Toronto, Ontario M5G 2M9, Canada., Pirikahu S; Genetic Epidemiology Group, School of Population and Global Health, The University of Western Australia, 35 Stirling Highway M431, Crawley, Western Australia 6009, Australia., Cadby G; Genetic Epidemiology Group, School of Population and Global Health, The University of Western Australia, 35 Stirling Highway M431, Crawley, Western Australia 6009, Australia., Hickey M; Department of Obstetrics and Gynaecology, University of Melbourne and the Royal Women's Hospital, Melbourne, Victoria 3052, Australia., Sampson DD; Surry Biophotonics, Advanced Technology Institute and School of Biosciences and Medicine, The University of Surrey, Guildford, Surrey GU2 7XH, United Kingdom., Karnowski K; Optical and Biomedical Engineering Laboratory School of Electrical, Electronic and Computer Engineering, The University of Western Australia, Crawley, Western Australia 6009, Australia., Hackmann MJ; Optical and Biomedical Engineering Laboratory School of Electrical, Electronic and Computer Engineering, The University of Western Australia, Crawley, Western Australia 6009, Australia., Saunders C; Medical School, The University of Western Australia, Crawley, Western Australia 6009, Australia., Lilge L; University Health Network, Toronto, Ontario M5G 2M9, Canada., Stone J; Genetic Epidemiology Group, School of Population and Global Health, The University of Western Australia, 35 Stirling Highway M431, Crawley, Western Australia 6009, Australia. |
| المصدر: | The Review of scientific instruments [Rev Sci Instrum] 2022 Apr 01; Vol. 93 (4), pp. 044101. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: American Institute Of Physics Country of Publication: United States NLM ID: 0405571 Publication Model: Print Cited Medium: Internet ISSN: 1089-7623 (Electronic) Linking ISSN: 00346748 NLM ISO Abbreviation: Rev Sci Instrum Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 1933- : Woodbury, N.Y. : American Institute Of Physics Original Publication: 1930-1932 : Menasha, WI : Optical Society of America |
| مواضيع طبية MeSH: | Breast Neoplasms*/diagnostic imaging , Mammography*, Breast/diagnostic imaging ; Female ; Humans ; Pilot Projects ; Spectrum Analysis |
| مستخلص: | Mammographic breast density is a strong breast cancer risk factor, and its routine clinical measurement could potentially be used to identify women at higher risk of breast cancer and/or monitor primary prevention strategies. Previous reports of optical breast spectroscopy (OBS), a novel approach to measuring breast density, demonstrated that it is safe (no ionizing radiation), portable, low-cost, and does not require image interpretation but have been limited to small, single-center studies. Reference measurements taken on a phantom breast prior to and after each woman's OBS assessment are required for the calibration of the system transfer function as a part of processing participant data. To inform the validity of participant data, a detailed description of the reference measurements and a repeatability analysis of these measurements taken before and after participant assessment is presented. Reference measurements for OBS from 539 women aged 18-40 years were obtained as a part of a high-throughput epidemiological pilot study. Of these, measurements from 20 women with no useable data due to device failure (3.7%) were excluded and from another 12 women due to user error. The intra-class correlation (ICC) within complete pairs of reference data (taken before and after assessment) was high (all ICC > 0.84). The analysis presented here confirms the OBS participant data as valid for use in ongoing epidemiological research, providing further supporting evidence of OBS as a measure of breast density. A novel method of measuring breast density is needed to bridge large gaps in the knowledge of breast density in younger women and its relation to later-life breast cancer risk. |
| تواريخ الأحداث: | Date Created: 20220430 Date Completed: 20220503 Latest Revision: 20240627 |
| رمز التحديث: | 20240627 |
| DOI: | 10.1063/5.0072223 |
| PMID: | 35489887 |
| قاعدة البيانات: | MEDLINE |
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