دورية أكاديمية
Platelet function testing: Current practice among clinical centres in Northern Europe.
| العنوان: | Platelet function testing: Current practice among clinical centres in Northern Europe. |
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| المؤلفون: | Szanto T; Coagulation Disorders Unit, Department of Hematology, Comprehensive Cancer Center, Helsinki University Hospital, Helsinki, Finland.; Research Program in Systems Oncology, Helsinki University, Helsinki, Finland., Zetterberg E; Department of Translational Medicine & Centre for Thrombosis and Haemostasis, Lund University, Malmö, Sweden., Ramström S; Department of Clinical Chemistry and Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.; School of Medical Sciences, Örebro University, Örebro, Sweden., Leinøe EB; Department of Haematology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Holme PA; Department of Haematology, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Antovic JP; Coagulation Research, Institute for Molecular Medicine and Surgery, Karolinska Institute & Department of Clinical Chemistry, Karolinska University Hospital, Stockholm, Sweden., Holmström M; Department of Health and Department of Acute Internal Medicine and Geriatrics, Medicine and Caring Sciences Linköping University, Linköping, Sweden., Onundarson PT; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Pikta M; Laboratory, North Estonia Medical Centre, Tallinn, Estonia., Vaide I; Department of Hemato-Oncology, University of Tartu, Institute of Clinical Medicine, Tartu, Estonia., Olsson A; Region Västra Götaland, Department of Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden., Magnusson M; Department of Haematology and Coagulation Disorders, Sahlgrenska University Hospital, Gothenburg, Sweden., Kärkkäinen S; Hemostasis and Platelet Laboratory, Fimlab Laboratoriot, Tampere, Finland., Bitar M; Department of Laboratory Medicine, Clinical Chemistry, Faculty of Medicine and Health, Örebro University Hospital, Örebro, Sweden., Poulsen LH; Centre for Haemophilia and Thrombosis, Aarhus University Hospital, Aarhus, Denmark., Lassila R; Coagulation Disorders Unit, Department of Hematology, Comprehensive Cancer Center, Helsinki University Hospital, Helsinki, Finland.; Research Program in Systems Oncology, Helsinki University, Helsinki, Finland. |
| مؤلفون مشاركون: | Nordic Haemophilia Council; Coagulation Disorders Unit, Department of Hematology, Comprehensive Cancer Center, Helsinki University Hospital, Helsinki, Finland. |
| المصدر: | Haemophilia : the official journal of the World Federation of Hemophilia [Haemophilia] 2022 Jul; Vol. 28 (4), pp. 642-648. Date of Electronic Publication: 2022 May 05. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Blackwell Science Country of Publication: England NLM ID: 9442916 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2516 (Electronic) Linking ISSN: 13518216 NLM ISO Abbreviation: Haemophilia Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Osney Mead, Oxford, UK : Blackwell Science, [1994- |
| مواضيع طبية MeSH: | Blood Platelet Disorders*/diagnosis , von Willebrand Diseases*/diagnosis, Blood Platelets ; Europe ; Hemorrhage/diagnosis ; Humans ; Platelet Function Tests |
| مستخلص: | Introduction: Platelet function tests are used to screen and diagnose patients with possible inherited platelet function defects (IPFD). Some acquired platelet dysfunction may be caused by certain drugs or comorbidities, which need to be excluded before testing. Aims: To identify current practice among centres performing platelet function tests in Northern Europe. Methods: A total of 14 clinical centres from Sweden (six), Finland (two), Denmark (two), Norway (one), Estonia (two) and Iceland (one) completed the survey questionnaire, the population capture area of about 29.5 million. Results: Six of the 14 (42.8%) centres providing platelet function assessment represent comprehensive treatment centres (EUHANET status). A Bleeding score (BS) or ISTH bleeding assessment tool (ISTH BAT score) is evaluated in 11/14 (78.6%) centres and family history in all. Five/14 centres (35.7%) use structured preanalytical patient instructions, and 10/14 (71.4%) recorded questionnaire on the preassessment of avoidance of any drugs or natural products affecting platelet functions. Preliminary investigations of screening tests of coagulation are performed in 10/14 (71.4%), while in 4/14 (28.6%), the diagnostic work-up of IPFD and von Willebrand disease (VWD) is performed simultaneously. The work-up of IPFD includes peripheral blood smear in 10/14 (71.4%), platelet aggregometry in all, flow cytometry in 10/14 (71.4%) and Platelet Function Analysis (PFA) in 3/11 (28.6%). Molecular genetic diagnosis is available in 7/14 (50%) centres. Conclusions: The considerable variability in the current practice illustrates the need for harmonization between the Northern European centres according to the international registers (i.e. EUHASS) and IPFD guidelines (ISTH, EHA). (© 2022 The Authors. Haemophilia published by John Wiley & Sons Ltd.) |
| References: | Blood Rev. 2021 Jul;48:100784. (PMID: 33317862) J Thromb Haemost. 2013 Apr 10;:. (PMID: 23574625) Am J Hematol. 2012 May;87 Suppl 1:S45-50. (PMID: 22367923) Int J Lab Hematol. 2009 Aug;31(4):398-406. (PMID: 18371058) J Thromb Haemost. 2017 Oct;15(10):2045-2052. (PMID: 28762630) Semin Thromb Hemost. 2016 Apr;42(3):292-305. (PMID: 26962877) J Thromb Haemost. 2020 Mar;18(3):732-739. (PMID: 31750621) Haematologica. 2007 Mar;92(3):357-65. (PMID: 17339185) J Thromb Haemost. 2006 Feb;4(2):312-9. (PMID: 16420557) Thromb Haemost. 2005 Mar;93(3):549-53. (PMID: 15735808) Blood. 2016 Jun 9;127(23):2814-23. (PMID: 27095789) Hemasphere. 2019 Sep 17;3(4):e286. (PMID: 31942541) Haemophilia. 2022 Jul;28(4):642-648. (PMID: 35510959) J Thromb Haemost. 2007 Feb;5(2):274-81. (PMID: 17137472) J Thromb Haemost. 2015 Feb;13(2):314-22. (PMID: 25403439) J Thromb Haemost. 2021 Dec;19(12):3193-3202. (PMID: 34580997) J Thromb Haemost. 2014 Sep;12(9):1562-9. (PMID: 24976115) J Thromb Haemost. 2021 May;19(5):1364-1371. (PMID: 33880867) J Clin Med. 2021 Mar 07;10(5):. (PMID: 33800006) J Clin Pathol. 2008 Aug;61(8):950-4. (PMID: 18663056) |
| فهرسة مساهمة: | Keywords: blood platelet disorders; data collection; platelet function testing; platelets; survey |
| تواريخ الأحداث: | Date Created: 20220505 Date Completed: 20220714 Latest Revision: 20221015 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC9540416 |
| DOI: | 10.1111/hae.14578 |
| PMID: | 35510959 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1365-2516 |
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| DOI: | 10.1111/hae.14578 |