دورية أكاديمية
Iron Supplementation at the Crossroads of Nutrition and Gut Microbiota: The State of the Art.
| العنوان: | Iron Supplementation at the Crossroads of Nutrition and Gut Microbiota: The State of the Art. |
|---|---|
| المؤلفون: | Puga AM; Grupo USP-CEU de Excelencia 'Nutrición para la vida (Nutrition for Life)', ref: E02/0720, Departamento de Ciencias Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, 28660 Boadilla del Monte, Spain., Samaniego-Vaesken ML; Grupo USP-CEU de Excelencia 'Nutrición para la vida (Nutrition for Life)', ref: E02/0720, Departamento de Ciencias Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, 28660 Boadilla del Monte, Spain., Montero-Bravo A; Grupo USP-CEU de Excelencia 'Nutrición para la vida (Nutrition for Life)', ref: E02/0720, Departamento de Ciencias Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, 28660 Boadilla del Monte, Spain., Ruperto M; Grupo USP-CEU de Excelencia 'Nutrición para la vida (Nutrition for Life)', ref: E02/0720, Departamento de Ciencias Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, 28660 Boadilla del Monte, Spain., Partearroyo T; Grupo USP-CEU de Excelencia 'Nutrición para la vida (Nutrition for Life)', ref: E02/0720, Departamento de Ciencias Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, 28660 Boadilla del Monte, Spain., Varela-Moreiras G; Grupo USP-CEU de Excelencia 'Nutrición para la vida (Nutrition for Life)', ref: E02/0720, Departamento de Ciencias Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, 28660 Boadilla del Monte, Spain. |
| المصدر: | Nutrients [Nutrients] 2022 May 04; Vol. 14 (9). Date of Electronic Publication: 2022 May 04. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Basel, Switzerland : MDPI Publishing |
| مواضيع طبية MeSH: | Anemia, Iron-Deficiency*/epidemiology , Gastrointestinal Microbiome*, Dietary Supplements ; Humans ; Iron ; Micronutrients |
| مستخلص: | Gut microbiota has received significant attention owing to its decisive role in human health and disease. Diet exerts a significant influence on the variety and number of bacteria residing in the intestinal epithelium. On the other hand, as iron is a key micronutrient for blood formation and oxygen supply, its deficiency is highly prevalent worldwide. In fact, it is the most common cause of anemia and thus, iron supplementation is widespread. However, there is concern due to some potential risks linked to iron supplementation. Therefore, we have reviewed the available evidence of the effects that iron supplementation exerts on the gut microbiota as well as its potential benefits and risks. The compiled information suggests that iron supplementation is potentially harmful for gut microbiota. Therefore, it should be performed with caution, and by principle, recommended only to individuals with proven iron deficiency or iron-deficiency anemia to avoid potential adverse effects. In any case, large and long-term population studies are urgently needed to confirm or refute these results, mainly focused on vulnerable populations. |
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| فهرسة مساهمة: | Keywords: gut microbiota; iron deficiency; iron fortification; iron status; iron supplementation; iron-deficiency anemia; microbiome; micronutrient powders |
| المشرفين على المادة: | 0 (Micronutrients) E1UOL152H7 (Iron) |
| تواريخ الأحداث: | Date Created: 20220514 Date Completed: 20220518 Latest Revision: 20220716 |
| رمز التحديث: | 20221213 |
| مُعرف محوري في PubMed: | PMC9102039 |
| DOI: | 10.3390/nu14091926 |
| PMID: | 35565894 |
| قاعدة البيانات: | MEDLINE |
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