دورية أكاديمية
Filariasis presenting as pancytopenia in a child.
| العنوان: | Filariasis presenting as pancytopenia in a child. |
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| المؤلفون: | Mandal AK; Pediatrics, Bankura Sammilani Medical College Bankura, Bankura, West Bengal, India anuskrish95@gmail.com., Jana JK; Pediatrics, Bankura Sammilani Medical College Bankura, Bankura, West Bengal, India., Gayen S; Pediatrics, Bankura Sammilani Medical College Bankura, Bankura, West Bengal, India., Pal AC; Pediatrics, Bankura Sammilani Medical College Bankura, Bankura, West Bengal, India. |
| المصدر: | BMJ case reports [BMJ Case Rep] 2022 May 23; Vol. 15 (5). Date of Electronic Publication: 2022 May 23. |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 101526291 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-790X (Electronic) Linking ISSN: 1757790X NLM ISO Abbreviation: BMJ Case Rep Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: London : BMJ Pub. Group |
| مواضيع طبية MeSH: | Elephantiasis, Filarial*/drug therapy , Filaricides*/therapeutic use , Pancytopenia*/drug therapy , Pancytopenia*/etiology, Albendazole/therapeutic use ; Animals ; Child ; Diethylcarbamazine/therapeutic use ; Drug Therapy, Combination ; Female ; Humans ; Ivermectin/therapeutic use ; Wuchereria bancrofti |
| مستخلص: | A female child hailing from South Asia, India presented with pallor, multiple petechiae and ecchymosis. Based on the clinical picture and demography, the differentials considered were pancytopenia of nutritional origin, acute leukaemia, autoimmune and infective aetiologies. After ruling these out by respective tests, a literature review was done which revealed the possibility of filariasis especially in a patient with eosinophilia which was present in our case. A repeat peripheral blood smear study with a nocturnally drawn sample revealed multiple microfilariae and a diagnosis of filariasis was made. The patient was treated with triple drug therapy of diethylcarbamazine (6 mg/kg), ivermectin (6 µg/kg) and albendazole (400 mg) administered as a single dose. Subsequent haemograms showed improved cell counts. This along with a previous handful of case reports emphasises filariasis as one of the differentials of pancytopenia and should be kept in mind while evaluating for the same, especially in the endemic areas. Competing Interests: Competing interests: None declared. (© BMJ Publishing Group Limited 2022. No commercial re-use. See rights and permissions. Published by BMJ.) |
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| فهرسة مساهمة: | Keywords: Haematology (incl blood transfusion); Infections; Paediatrics |
| المشرفين على المادة: | 0 (Filaricides) 70288-86-7 (Ivermectin) F4216019LN (Albendazole) V867Q8X3ZD (Diethylcarbamazine) |
| تواريخ الأحداث: | Date Created: 20220523 Date Completed: 20220525 Latest Revision: 20240524 |
| رمز التحديث: | 20240524 |
| مُعرف محوري في PubMed: | PMC9174759 |
| DOI: | 10.1136/bcr-2022-248930 |
| PMID: | 35606041 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1757-790X |
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| DOI: | 10.1136/bcr-2022-248930 |