دورية أكاديمية
Four New Highly Oxygenated Eremophilane Sesquiterpenes from an Endophytic Fungus Boeremia exigua Isolated from Fritillaria hupehensis .
| العنوان: | Four New Highly Oxygenated Eremophilane Sesquiterpenes from an Endophytic Fungus Boeremia exigua Isolated from Fritillaria hupehensis . |
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| المؤلفون: | Ai HL; School of Pharmaceutical Sciences, South-Central MinZu University, Wuhan 430074, China., Lv X; School of Pharmaceutical Sciences, South-Central MinZu University, Wuhan 430074, China., Ye K; School of Pharmaceutical Sciences, South-Central MinZu University, Wuhan 430074, China., Wang MX; School of Pharmaceutical Sciences, South-Central MinZu University, Wuhan 430074, China., Huang R; School of Pharmaceutical Sciences, South-Central MinZu University, Wuhan 430074, China., Shi BB; School of Pharmaceutical Sciences, South-Central MinZu University, Wuhan 430074, China., Li ZH; School of Pharmaceutical Sciences, South-Central MinZu University, Wuhan 430074, China. |
| المصدر: | Journal of fungi (Basel, Switzerland) [J Fungi (Basel)] 2022 May 08; Vol. 8 (5). Date of Electronic Publication: 2022 May 08. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101671827 Publication Model: Electronic Cited Medium: Internet ISSN: 2309-608X (Electronic) Linking ISSN: 2309608X NLM ISO Abbreviation: J Fungi (Basel) Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Basel, Switzerland : MDPI AG, [2015]- |
| مستخلص: | Four new eremophilane-type sesquiterpenes, boeremialanes A-D ( 1 - 4 ) were obtained from solid substrate cultures of Boeremia exigua (Didymellaceae), an endophytic fungus isolated from Fritillaria hupehensis (Liliaceae). Boeremialanes A-C ( 1 - 3 ) are highly oxygenated eremophilanes with a benzoate unit attached at the C-13 position and are rarely found in nature. Their structures and absolute configurations were determined by extensive spectroscopic methods, electronic circular dichroism (ECD), and nuclear magnetic resonance (NMR) calculations with DP4+ analysis. Boeremialane D ( 4 ) potently inhibited nitric oxide production in lipopolysaccharide-treated RAW264.7 macrophages with an IC |
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| معلومات مُعتمدة: | 31870513 National Natural Science Foundation of China; CZD21003 Fundamental Research Funds for the Central Universities, South-Central MinZu University |
| فهرسة مساهمة: | Keywords: Boeremia exigua; Fritillaria hupehensis; NO production inhibition; anti-inflammatory; boeremialanes; eremophilanes |
| تواريخ الأحداث: | Date Created: 20220528 Latest Revision: 20220716 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC9146970 |
| DOI: | 10.3390/jof8050492 |
| PMID: | 35628748 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2309-608X |
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| DOI: | 10.3390/jof8050492 |