دورية أكاديمية
Codependence of individuals in the Nephromyces species swarm requires heterospecific bacterial endosymbionts.
| العنوان: | Codependence of individuals in the Nephromyces species swarm requires heterospecific bacterial endosymbionts. |
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| المؤلفون: | Paight C; Department of Biological Sciences, University of Rhode Island, Kingston, RI 02881, USA., Hunter ES; Department of Biological Sciences, University of Rhode Island, Kingston, RI 02881, USA., Lane CE; Department of Biological Sciences, University of Rhode Island, Kingston, RI 02881, USA. Electronic address: clane@uri.edu. |
| المصدر: | Current biology : CB [Curr Biol] 2022 Jul 11; Vol. 32 (13), pp. 2948-2955.e4. Date of Electronic Publication: 2022 May 27. |
| نوع المنشور: | Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. |
| اللغة: | English |
| بيانات الدورية: | Publisher: Cell Press Country of Publication: England NLM ID: 9107782 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0445 (Electronic) Linking ISSN: 09609822 NLM ISO Abbreviation: Curr Biol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Cambridge, MA : Cell Press Original Publication: London, UK : Current Biology Ltd., c1991- |
| مواضيع طبية MeSH: | Apicomplexa* , Urochordata*/genetics, Animals ; Bacteria/genetics ; Codependency, Psychological ; Genome, Bacterial ; Phylogeny ; Symbiosis |
| مستخلص: | Symbiosis is one of the most important evolutionary processes shaping the biodiversity on Earth. Symbiotic associations often bring together organisms from different domains of life, which can provide an unparalleled route to evolutionary innovation. 1-4 The phylum Apicomplexa encompasses 6,000 ubiquitous animal parasites; however, species in the recently described apicomplexan family, Nephromycidae, are reportedly non-virulent. 5 , 6 The members of the genus Nephromyces live within a specialized organ of tunicates, called the renal sac, in which they use concentrated uric acid as a primary nitrogen source. 7 , 8 Here, we report genomic and transcriptomic data from the diverse genus Nephromyces, as well as the three bacterial symbionts that live within this species complex. We show that the diversity of Nephromyces is unexpectedly high within each renal sac, with as many as 20 different species inhabiting the renal sacs in wild populations. The many species of Nephromyces can host three different types of bacterial endosymbionts; however, FISH microscopy allowed us to demonstrate that each individual Nephromyces cell hosts only a single bacterial type. Through the reconstruction and analyses of the endosymbiont bacterial genomes, we infer that each bacterial type supplies its host with different metabolites. No individual species of Nephromyces, in combination with its endosymbiont, can produce a complete set of essential amino acids, and culture experiments demonstrate that individual Nephromyces species cannot form a viable infection. Therefore, we hypothesize that Nephromyces spp. depend on co-infection with congeners containing different bacterial symbionts in order to exchange metabolites to meet their needs. Competing Interests: Declaration of interests The authors declare no competing interests. (Copyright © 2022 Elsevier Inc. All rights reserved.) |
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| معلومات مُعتمدة: | R03 AI124092 United States AI NIAID NIH HHS |
| فهرسة مساهمة: | Keywords: apicomplexa; endosymbiosis; evolution; genomics; symbiosis; transcriptomics |
| تواريخ الأحداث: | Date Created: 20220601 Date Completed: 20220714 Latest Revision: 20230712 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC9283375 |
| DOI: | 10.1016/j.cub.2022.05.007 |
| PMID: | 35643082 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1879-0445 |
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| DOI: | 10.1016/j.cub.2022.05.007 |