دورية أكاديمية
Provocation and localization of atrial ectopy in patients with atrial septal defects.
| العنوان: | Provocation and localization of atrial ectopy in patients with atrial septal defects. |
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| المؤلفون: | O'Neill L; Division of Imaging Sciences and Biomedical Engineering, King's College London, 4thFloor North Wing, St. Thomas' Hospital, London, SE1 7EH, UK. louisa.oneill@kcl.ac.uk., Sim I; Division of Imaging Sciences and Biomedical Engineering, King's College London, 4thFloor North Wing, St. Thomas' Hospital, London, SE1 7EH, UK., O'Hare D; Division of Imaging Sciences and Biomedical Engineering, King's College London, 4thFloor North Wing, St. Thomas' Hospital, London, SE1 7EH, UK., Whitaker J; Division of Imaging Sciences and Biomedical Engineering, King's College London, 4thFloor North Wing, St. Thomas' Hospital, London, SE1 7EH, UK., Mukherjee RK; Division of Imaging Sciences and Biomedical Engineering, King's College London, 4thFloor North Wing, St. Thomas' Hospital, London, SE1 7EH, UK., Niederer S; Division of Imaging Sciences and Biomedical Engineering, King's College London, 4thFloor North Wing, St. Thomas' Hospital, London, SE1 7EH, UK., Wright M; Division of Imaging Sciences and Biomedical Engineering, King's College London, 4thFloor North Wing, St. Thomas' Hospital, London, SE1 7EH, UK., Ezzat V; Bart's Heart Centre, London, UK., Rosenthal E; Guy's and St Thomas' NHS Foundation Trust, London, UK., Jones MI; Guy's and St Thomas' NHS Foundation Trust, London, UK., Frigiola A; Guy's and St Thomas' NHS Foundation Trust, London, UK., O'Neill MD; Division of Imaging Sciences and Biomedical Engineering, King's College London, 4thFloor North Wing, St. Thomas' Hospital, London, SE1 7EH, UK., Williams SE; Division of Imaging Sciences and Biomedical Engineering, King's College London, 4thFloor North Wing, St. Thomas' Hospital, London, SE1 7EH, UK.; The University of Edinburgh, Edinburgh, UK. |
| المصدر: | Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing [J Interv Card Electrophysiol] 2022 Oct; Vol. 65 (1), pp. 227-237. Date of Electronic Publication: 2022 Jun 23. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Springer Country of Publication: Netherlands NLM ID: 9708966 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1572-8595 (Electronic) Linking ISSN: 1383875X NLM ISO Abbreviation: J Interv Card Electrophysiol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Amsterdam : Springer Original Publication: Norwell, MA : Kluwer Academic Publishers, c1997- |
| مواضيع طبية MeSH: | Atrial Fibrillation* , Heart Septal Defects, Atrial*/complications , Heart Septal Defects, Atrial*/diagnostic imaging, Cohort Studies ; Electrocardiography, Ambulatory ; Humans ; Isoproterenol |
| مستخلص: | Background: Atrial fibrillation (AF) is associated with atrial septal defects (ASDs), but the mechanism of arrhythmia in these patients is poorly understood. We hypothesised that right-sided atrial ectopy may predominate in this cohort. Here, we aimed to localise the origin of spontaneous and provoked atrial ectopy in ASD patients. Methods: Following invasive calibration of P-wave axes, 24-h Holter monitoring was used to determine the chamber of origin of spontaneous atrial ectopy. Simultaneous electrogram recording from multiple intra-cardiac catheters was used to determine the chamber of origin of isoprenaline-provoked ectopy. Comparison was made to a group of non-congenital heart disease AF patients. Results: Amongst ASD patients, a right-sided origin for spontaneous atrial ectopy was significantly more prevalent than a left-sided origin (24/30 patients with right-sided ectopy vs. 14/30 with left-sided ectopy, P = 0.015). Amongst AF patients, there was no difference in the prevalence of spontaneous right vs. left-sided ectopy. For isoprenaline-provoked ectopy, there was no significant difference in the proportions of patients with right-sided or left-sided ectopy in either group. Conclusions: When spontaneous atrial ectopy occurs in ASD patients, it is significantly more prevalent from a right-sided than left-sided origin. Isoprenaline infusion did not reveal the predilection for right-sided ectopy during electrophysiology study. (© 2022. The Author(s).) |
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| معلومات مُعتمدة: | United Kingdom WT_ Wellcome Trust; WT 203148/Z/16/Z United Kingdom WT_ Wellcome Trust |
| فهرسة مساهمة: | Keywords: Atrial arrhythmia; Atrial ectopy; Atrial septal defect; Right atrium |
| المشرفين على المادة: | L628TT009W (Isoproterenol) |
| تواريخ الأحداث: | Date Created: 20220623 Date Completed: 20221012 Latest Revision: 20221013 |
| رمز التحديث: | 20240829 |
| مُعرف محوري في PubMed: | PMC9550781 |
| DOI: | 10.1007/s10840-022-01273-2 |
| PMID: | 35737208 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1572-8595 |
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| DOI: | 10.1007/s10840-022-01273-2 |