دورية أكاديمية
أعرض في EDS

Genetic disruption of Arabidopsis secondary metabolite synthesis leads to microbiome-mediated modulation of nematode invasion.

التفاصيل البيبلوغرافية
العنوان: Genetic disruption of Arabidopsis secondary metabolite synthesis leads to microbiome-mediated modulation of nematode invasion.
المؤلفون: Sikder MM; Department of Agroecology, Faculty of Technical Sciences, Aarhus University, 4200, Slagelse, Denmark.; Department of Botany, Faculty of Biological Sciences, Jahangirnagar University, 1342 Savar, Dhaka, Bangladesh., Vestergård M; Department of Agroecology, Faculty of Technical Sciences, Aarhus University, 4200, Slagelse, Denmark., Kyndt T; Department of Biotechnology, Faculty of Bioscience Engineering, Ghent University, 9000, Gent, Belgium., Topalović O; Department of Agroecology, Faculty of Technical Sciences, Aarhus University, 4200, Slagelse, Denmark., Kudjordjie EN; Department of Agroecology, Faculty of Technical Sciences, Aarhus University, 4200, Slagelse, Denmark., Nicolaisen M; Department of Agroecology, Faculty of Technical Sciences, Aarhus University, 4200, Slagelse, Denmark. mn@agro.au.dk.
المصدر: The ISME journal [ISME J] 2022 Sep; Vol. 16 (9), pp. 2230-2241. Date of Electronic Publication: 2022 Jun 27.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101301086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1751-7370 (Electronic) Linking ISSN: 17517362 NLM ISO Abbreviation: ISME J Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : Nature Pub. Group
مواضيع طبية MeSH: Arabidopsis*/genetics , Solanum lycopersicum*/genetics , Solanum lycopersicum*/microbiology , Solanum lycopersicum*/parasitology , Microbiota* , Tylenchoidea*/genetics, Animals ; Flavonoids ; Plant Roots/genetics
مستخلص: In-depth understanding of metabolite-mediated plant-nematode interactions can guide us towards novel nematode management strategies. To improve our understanding of the effects of secondary metabolites on soil nematode communities, we grew Arabidopsis thaliana genetically altered in glucosinolate, camalexin, or flavonoid synthesis pathways, and analyzed their root-associated nematode communities using metabarcoding. To test for any modulating effects of the associated microbiota on the nematode responses, we characterized the bacterial and fungal communities. Finally, as a proxy of microbiome-modulating effects on nematode invasion, we isolated the root-associated microbiomes from the mutants and tested their effect on the ability of the plant parasitic nematode Meloidogyne incognita to penetrate tomato roots. Most mutants had altered relative abundances of several nematode taxa with stronger effects on the plant parasitic Meloidogyne hapla than on other root feeding taxa. This probably reflects that M. hapla invades and remains embedded within root tissues and is thus intimately associated with the host. When transferred to tomato, microbiomes from the flavonoid over-producing pap1-D enhanced M. incognita root-invasion, whereas microbiomes from flavonoid-deficient mutants reduced invasion. This suggests microbiome-mediated effect of flavonoids on Meloidogyne infectivity plausibly mediated by the alteration of the abundances of specific microbial taxa in the transferred microbiomes, although we could not conclusively pinpoint such causative microbial taxa.
(© 2022. The Author(s), under exclusive licence to International Society for Microbial Ecology.)
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معلومات مُعتمدة: 6111-00065B Det Frie Forskningsråd (Danish Council for Independent Research); 9041-00139B Det Frie Forskningsråd (Danish Council for Independent Research); 27747 Aarhus Universitet (Aarhus University)
المشرفين على المادة: 0 (Flavonoids)
تواريخ الأحداث: Date Created: 20220627 Date Completed: 20220818 Latest Revision: 20230902
رمز التحديث: 20230902
مُعرف محوري في PubMed: PMC9381567
DOI: 10.1038/s41396-022-01276-x
PMID: 35760884
قاعدة البيانات: MEDLINE
الوصف
تدمد:1751-7370
DOI:10.1038/s41396-022-01276-x