دورية أكاديمية
Evaluation of TyG index and TG/HDL-C ratio in HBeAg negative chronic hepatitis B infected patients.
| العنوان: | Evaluation of TyG index and TG/HDL-C ratio in HBeAg negative chronic hepatitis B infected patients. |
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| المؤلفون: | Ünver Ulusoy T; University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Infectious Diseases and Clinical Microbiology, Ankara, Turkey., Bilek HC; Ondokuz Mayıs University Faculty of Medicine, Infectious Diseases and Clinical Microbiology, Samsun, Turkey., Demirköse H; Pursaklar District Health Directorate, Public Health, Ankara, Turkey., Keleş A; Yıldırım Beyazıt University Yenimahalle Training and Research Hospital, Biochemistry, Ankara, Turkey. |
| المصدر: | Biomolecules & biomedicine [Biomol Biomed] 2023 Feb 01; Vol. 23 (1), pp. 137-144. Date of Electronic Publication: 2023 Feb 01. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Association of Basic Medical Sciences of FBIH Country of Publication: Bosnia and Herzegovina NLM ID: 9918522188506676 Publication Model: Electronic Cited Medium: Internet ISSN: 2831-090X (Electronic) Linking ISSN: 28310896 NLM ISO Abbreviation: Biomol Biomed Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Sarajevo : Association of Basic Medical Sciences of FBIH, [2023]- |
| مواضيع طبية MeSH: | Hepatitis B, Chronic* , Insulin Resistance* , D-Alanine Transaminase*, Humans ; Middle Aged ; Hepatitis B e Antigens ; Body Mass Index ; Glucose ; Alanine Transaminase |
| مستخلص: | Patients with hepatitis B e antigen (HBeAg) negative chronic HBV infection are regularly followed up. This study investigates the presence of insulin resistance and the relationship between hepatosteatosis and insulin resistance in patients with HBeAg negative chronic HBV infection using the TyG index and TG/HDL-C ratio. Patients with HBeAg negative chronic HBV infection who applied to the Infectious Diseases and Clinical Microbiology outpatient clinic between January 2019 and December 2020 were included in the study. Glucose, lipid panel, alanine amino transferase (ALT), acetyl amino transferase (AST), body mass index (BMI), TyG index, TG/HDL-C and hepatobiliary ultrasonography (USG) results were evaluated. The data were compared with the control group consisting of 308 HBsAg negative individuals. The study included 132 patients with a median age of 52 years. There was no significant difference between the patient and control groups regarding age, gender and BMI. Glucose, total cholesterol, TG, LDL, AST, ALT, TyG index and TG/HDL-C ratio were significantly higher in patient than in the control group. At the same time, the HDL value was significantly lower in the patients. There was a strong positive correlation between the TG and BMI, and a strong negative correlation between HDL levels and both TyG index and TG/HDL-C ratio. Our findings showed that the TyG index and TG/HDL-C ratio are helpful in the diagnosis of insulin resistance and hepatosteatosis in patients with HBeAg negative chronic HBV infection. |
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| المشرفين على المادة: | 0 (Hepatitis B e Antigens) IY9XDZ35W2 (Glucose) EC 2.6.1.2 (Alanine Transaminase) EC 2.6.1.21 (D-Alanine Transaminase) |
| تواريخ الأحداث: | Date Created: 20220629 Date Completed: 20230202 Latest Revision: 20230208 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC9901891 |
| DOI: | 10.17305/bjbms.2022.7320 |
| PMID: | 35765946 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2831-090X |
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| DOI: | 10.17305/bjbms.2022.7320 |