دورية أكاديمية
أعرض في EDS

Nanoparticles-based anti-aging treatment of Alzheimer's disease.

التفاصيل البيبلوغرافية
العنوان: Nanoparticles-based anti-aging treatment of Alzheimer's disease.
المؤلفون: Chu JJ; Second Affiliated Hospital (Changzheng Hospital) of Naval Medical University, Shanghai, China.; Changhai Clinical Research Unit, Shanghai Changhai Hospital, Naval Medical University, Shanghai, China., Ji WB; Second Affiliated Hospital (Changzheng Hospital) of Naval Medical University, Shanghai, China.; Changhai Clinical Research Unit, Shanghai Changhai Hospital, Naval Medical University, Shanghai, China., Zhuang JH; Second Affiliated Hospital (Changzheng Hospital) of Naval Medical University, Shanghai, China., Gong BF; Second Affiliated Hospital (Changzheng Hospital) of Naval Medical University, Shanghai, China., Chen XH; Second Affiliated Hospital (Changzheng Hospital) of Naval Medical University, Shanghai, China., Cheng WB; Second Affiliated Hospital (Changzheng Hospital) of Naval Medical University, Shanghai, China., Liang WD; Second Affiliated Hospital (Changzheng Hospital) of Naval Medical University, Shanghai, China., Li GR; Second Affiliated Hospital (Changzheng Hospital) of Naval Medical University, Shanghai, China., Gao J; Changhai Clinical Research Unit, Shanghai Changhai Hospital, Naval Medical University, Shanghai, China., Yin Y; Second Affiliated Hospital (Changzheng Hospital) of Naval Medical University, Shanghai, China.
المصدر: Drug delivery [Drug Deliv] 2022 Dec; Vol. 29 (1), pp. 2100-2116.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9417471 Publication Model: Print Cited Medium: Internet ISSN: 1521-0464 (Electronic) Linking ISSN: 10717544 NLM ISO Abbreviation: Drug Deliv Subsets: MEDLINE
أسماء مطبوعة: Publication: 2015->: Abingdon, Oxford : Taylor & Francis
Original Publication: Orlando, FL : Academic Press, c1993-
مواضيع طبية MeSH: Alzheimer Disease*/drug therapy , Nanoparticles*, Aging ; Biological Transport ; Blood-Brain Barrier ; Humans
مستخلص: Age is the strongest risk factor for Alzheimer's disease (AD). In recent years, the relationship between aging and AD has been widely studied, with anti-aging therapeutics as the treatment for AD being one of the mainstream research directions. Therapeutics targeting senescent cells have shown improvement in AD symptoms and cerebral pathological changes, suggesting that anti-aging strategies may be a promising alternative for AD treatment. Nanoparticles represent an excellent approach for efficiently crossing the blood-brain barrier (BBB) to achieve better curative function and fewer side effects. Thereby, nanoparticles-based anti-aging treatment may exert potent anti-AD therapeutic efficacy. This review discusses the relationship between aging and AD and the application and prospect of anti-aging strategies and nanoparticle-based therapeutics in treating AD.
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فهرسة مساهمة: Keywords: AD; BBB; anti-aging; anti-inflammation; nanoparticles; senescent cells
تواريخ الأحداث: Date Created: 20220719 Date Completed: 20220720 Latest Revision: 20220723
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC9302016
DOI: 10.1080/10717544.2022.2094501
PMID: 35850622
قاعدة البيانات: MEDLINE
الوصف
تدمد:1521-0464
DOI:10.1080/10717544.2022.2094501