دورية أكاديمية
[Association between depression and viral load in people on antiretroviral treatment followed at the Yaoundé Central Hospital in Cameroon].
| العنوان: | [Association between depression and viral load in people on antiretroviral treatment followed at the Yaoundé Central Hospital in Cameroon]. |
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| عنوان ترانسليتريتد: | Association entre dépression et charge virale chez les personnes sous traitement antirétroviral suivies à l´Hôpital Central de Yaoundé au Cameroun. |
| المؤلفون: | Voundi EV; Faculté de Médecine et des Sciences Biomédicales, Université de Yaoundé I, Yaoundé, Cameroun., Kalla GCM; Faculté de Médecine et des Sciences Biomédicales, Université de Yaoundé I, Yaoundé, Cameroun., Kenfack JDT; Faculté de Médecine et des Sciences Biomédicales, Université de Yaoundé I, Yaoundé, Cameroun., Olen JPK; Faculté de Médecine et des Sciences Biomédicales, Université de Yaoundé I, Yaoundé, Cameroun., Essi MJ; Faculté de Médecine et des Sciences Biomédicales, Université de Yaoundé I, Yaoundé, Cameroun., Mbopi-Keou FX; Faculté de Médecine et des Sciences Biomédicales, Université de Yaoundé I, Yaoundé, Cameroun.; Institut pour le Développement de l´Afrique (The-IDA), Yaoundé, Cameroun. |
| المصدر: | The Pan African medical journal [Pan Afr Med J] 2022 Apr 20; Vol. 41, pp. 320. Date of Electronic Publication: 2022 Apr 20 (Print Publication: 2022). |
| نوع المنشور: | Journal Article |
| اللغة: | French |
| بيانات الدورية: | Publisher: African Field Epidemiology Network Country of Publication: Uganda NLM ID: 101517926 Publication Model: eCollection Cited Medium: Internet ISSN: 1937-8688 (Electronic) NLM ISO Abbreviation: Pan Afr Med J Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Kampala, Uganda : African Field Epidemiology Network |
| مواضيع طبية MeSH: | Depression*/epidemiology , Depression*/etiology , HIV Infections*/drug therapy , HIV Infections*/epidemiology, Adult ; Anti-Retroviral Agents/therapeutic use ; Cameroon ; Cross-Sectional Studies ; Female ; Hospitals ; Humans ; Middle Aged ; Quality of Life ; Viral Load |
| مستخلص: | Introduction: depression may be associated with poor immune and virological response, poor quality of life and high medical costs in people living with HIV. The purpose of this study is to investigate the association between depression and viral load in people living with HIV on antiretroviral treatment followed at the Yaounde Central Hospital. Methods: we conducted a cross-sectional study of people living with HIV who had their viral load results at the Central Hospital of Yaounde over 8 months (November 2019 to July 2020). Before starting the study, informed consent was obtained from each participant. Sociodemographic, clinical, paraclinical and lifestyle data were collected. Depression was assessed using the Hospital Anxiety and Depression scale (HAD). Consecutive and non-probability sampling was used. Statistical analysis was performed using SPSS software version 23.0. A p-value < 0.05 was considered statistically significant. Results: of the 205 participants enrolled, female sex was the most represented (n=153, 74.6%) and the mean age was 46.5 ± 1.8 years. All participants had clinical stage I HIV and most of them had undetectable viral load (n=164, 80.0%). Definite depression was found in 4.8% of cases and people living with HIV with symptoms of definite depression were more likely to have a high viral load (OR = 14.24 [3.61-56.14]; p = <0.001). Conclusion: depression could be a leading cause of high viral load. Competing Interests: Les auteurs déclarent n´avoir aucun conflit d´intérêts. (Copyright: Esther Voundi Voundi et al.) |
| References: | PLoS One. 2013 Aug 26;8(8):e72680. (PMID: 23991142) Rev Esp Salud Publica. 2006 Jan-Feb;80(1):41-54. (PMID: 16553259) Pan Afr Med J. 2012;12:55. (PMID: 22937195) Am J Psychiatry. 2002 Oct;159(10):1752-9. (PMID: 12359683) Nutrients. 2022 Jan 25;14(3):. (PMID: 35276881) Pac AIDS Alert Bull. 1999;(18):15-6. (PMID: 12349391) BMC Psychiatry. 2019 Nov 1;19(1):333. (PMID: 31675938) Pan Afr Med J. 2015 Apr 27;20:412. (PMID: 26301016) HIV Med. 2017 Jul;18(6):383-394. (PMID: 27625202) AIDS Care. 2004 Feb;16(2):177-86. (PMID: 14676024) Health Psychol. 2004 Jul;23(4):363-70. (PMID: 15264972) Curr HIV/AIDS Rep. 2014 Sep;11(3):291-307. (PMID: 25038748) Acta Psychiatr Scand. 1983 Jun;67(6):361-70. (PMID: 6880820) AIDS Res Hum Retroviruses. 2016 Apr;32(4):329-33. (PMID: 26602836) PLoS One. 2017 Aug 4;12(8):e0181960. (PMID: 28783739) Ann Intern Med. 2000 Jul 4;133(1):21-30. (PMID: 10877736) Indian J Pharmacol. 2015 Nov-Dec;47(6):672-5. (PMID: 26729962) |
| فهرسة مساهمة: | Keywords: Cameroon; Human immunodeficiency virus; Yaounde; depression; viral load |
| المشرفين على المادة: | 0 (Anti-Retroviral Agents) |
| تواريخ الأحداث: | Date Created: 20220722 Date Completed: 20220725 Latest Revision: 20240831 |
| رمز التحديث: | 20240831 |
| مُعرف محوري في PubMed: | PMC9269042 |
| DOI: | 10.11604/pamj.2022.41.320.33056 |
| PMID: | 35865857 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1937-8688 |
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| DOI: | 10.11604/pamj.2022.41.320.33056 |