دورية أكاديمية

Early coronary angiography in patients after out-of-hospital cardiac arrest without ST-segment elevation: Meta-analysis of randomized controlled trials.

التفاصيل البيبلوغرافية
العنوان: Early coronary angiography in patients after out-of-hospital cardiac arrest without ST-segment elevation: Meta-analysis of randomized controlled trials.
المؤلفون: Freund A; Department of Internal Medicine/Cardiology, Heart Center Leipzig at the University of Leipzig and Leipzig Heart Institute, Leipzig, Germany.; DZHK (German Center for Cardiovascular Research), Berlin, Germany., van Royen N; Department of Cardiology, Radboud University Medical Center, Nijmegen, The Netherlands., Kern KB; Department of Medicine, Sarver Heart Center, University of Arizona, Tucson, USA., Jobs A; Department of Internal Medicine/Cardiology, Heart Center Leipzig at the University of Leipzig and Leipzig Heart Institute, Leipzig, Germany.; DZHK (German Center for Cardiovascular Research), Berlin, Germany.; University Heart Center Lübeck, University Hospital Schleswig-Holstein, Lübeck, Germany., Thiele H; Department of Internal Medicine/Cardiology, Heart Center Leipzig at the University of Leipzig and Leipzig Heart Institute, Leipzig, Germany., Lemkes JS; Department of Cardiology, Amsterdam University Medical Center, Amsterdam, the Netherlands., Desch S; Department of Internal Medicine/Cardiology, Heart Center Leipzig at the University of Leipzig and Leipzig Heart Institute, Leipzig, Germany.; DZHK (German Center for Cardiovascular Research), Berlin, Germany.; University Heart Center Lübeck, University Hospital Schleswig-Holstein, Lübeck, Germany.
مؤلفون مشاركون: TOMAHAWK, PEARL, and COACT investigators
المصدر: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions [Catheter Cardiovasc Interv] 2022 Sep; Vol. 100 (3), pp. 330-337. Date of Electronic Publication: 2022 Jul 28.
نوع المنشور: Journal Article; Meta-Analysis
اللغة: English
بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 100884139 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-726X (Electronic) Linking ISSN: 15221946 NLM ISO Abbreviation: Catheter Cardiovasc Interv Subsets: MEDLINE
أسماء مطبوعة: Original Publication: New York, NY : Wiley-Liss, c1999-
مواضيع طبية MeSH: Out-of-Hospital Cardiac Arrest*/diagnostic imaging , Out-of-Hospital Cardiac Arrest*/etiology , Out-of-Hospital Cardiac Arrest*/therapy , Percutaneous Coronary Intervention*/adverse effects, Coronary Angiography/methods ; Humans ; Randomized Controlled Trials as Topic ; Time Factors ; Treatment Outcome
مستخلص: Objectives: To compare early coronary angiography to a delayed or selective approach in out-of-hospital cardiac arrest (OHCA) without ST-segment elevation of possible cardiac cause by means of meta-analysis of available randomized controlled trials (RCTs).
Methods: We searched MEDLINE and the Cochrane Central Register of Controlled Trials for RCTs comparing early with delayed or selective coronary angiography in OHCA patients of possible cardiac origin without ST-segment elevation. The primary endpoint was all-cause short-term mortality (PROSPERO CRD42021271484).
Results: The search strategy identified three RCTs enrolling a total of 1167 patients. An early invasive approach was not associated with improved short-term mortality (odds ratio 1.19, 95% confidence interval 0.94-1.52; p = 0.15). Further, no significant differences were shown with respect to the risk of severe neurological deficit, the composite of all-cause mortality or severe neurological deficit, need for renal replacement therapy due to acute renal failure, and significant bleeding at short-term follow-up.
Conclusion: Early coronary angiography in OHCA without ST-segment elevation is not superior compared to a delayed/selective approach.
(© 2022 The Authors. Catheterization and Cardiovascular Interventions published by Wiley Periodicals LLC.)
التعليقات: Comment in: Catheter Cardiovasc Interv. 2022 Sep;100(3):338-339. (PMID: 36084188)
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فهرسة مساهمة: Keywords: coronary angiography; out-of-hospital cardiac arrest; survival
تواريخ الأحداث: Date Created: 20220728 Date Completed: 20220913 Latest Revision: 20220921
رمز التحديث: 20231215
DOI: 10.1002/ccd.30355
PMID: 35900214
قاعدة البيانات: MEDLINE