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Exploring the medicinally important secondary metabolites landscape through the lens of transcriptome data in fenugreek (Trigonella foenum graecum L.).

التفاصيل البيبلوغرافية
العنوان: Exploring the medicinally important secondary metabolites landscape through the lens of transcriptome data in fenugreek (Trigonella foenum graecum L.).
المؤلفون: Naika MBN; National Centre for Biological Sciences (TIFR), GKVK Campus, Bengaluru, India.; Department of Biotechnology and Crop Improvement, K.R.C. College of Horticulture, University of Horticultural Sciences-Bagalkot, Arabhavi, Karnataka, 591218, India., Sathyanarayanan N; National Centre for Biological Sciences (TIFR), GKVK Campus, Bengaluru, India.; The University of Trans-Disciplinary Health Sciences & Technology (TDU), Yelahanka, Bengaluru, Karnataka, 560064, India., Sajeevan RS; National Centre for Biological Sciences (TIFR), GKVK Campus, Bengaluru, India., Bhattacharyya T; National Centre for Biological Sciences (TIFR), GKVK Campus, Bengaluru, India., Ghosh P; National Centre for Biological Sciences (TIFR), GKVK Campus, Bengaluru, India., Iyer MS; National Centre for Biological Sciences (TIFR), GKVK Campus, Bengaluru, India., Jarjapu M; National Centre for Biological Sciences (TIFR), GKVK Campus, Bengaluru, India., Joshi AG; National Centre for Biological Sciences (TIFR), GKVK Campus, Bengaluru, India., Harini K; National Centre for Biological Sciences (TIFR), GKVK Campus, Bengaluru, India., Shafi KM; National Centre for Biological Sciences (TIFR), GKVK Campus, Bengaluru, India.; The University of Trans-Disciplinary Health Sciences & Technology (TDU), Yelahanka, Bengaluru, Karnataka, 560064, India., Kalmankar N; National Centre for Biological Sciences (TIFR), GKVK Campus, Bengaluru, India.; The University of Trans-Disciplinary Health Sciences & Technology (TDU), Yelahanka, Bengaluru, Karnataka, 560064, India., Karpe SD; National Centre for Biological Sciences (TIFR), GKVK Campus, Bengaluru, India., Mam B; National Centre for Biological Sciences (TIFR), GKVK Campus, Bengaluru, India.; The University of Trans-Disciplinary Health Sciences & Technology (TDU), Yelahanka, Bengaluru, Karnataka, 560064, India., Pasha SN; National Centre for Biological Sciences (TIFR), GKVK Campus, Bengaluru, India., Sowdhamini R; National Centre for Biological Sciences (TIFR), GKVK Campus, Bengaluru, India. mini@ncbs.res.in.
المصدر: Scientific reports [Sci Rep] 2022 Aug 08; Vol. 12 (1), pp. 13534. Date of Electronic Publication: 2022 Aug 08.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : Nature Publishing Group, copyright 2011-
مواضيع طبية MeSH: Diosgenin*/metabolism , Plants, Medicinal*/genetics , Plants, Medicinal*/metabolism , Trigonella*/genetics , Trigonella*/metabolism, Hypoglycemic Agents/metabolism ; Plant Extracts/metabolism ; Transcriptome
مستخلص: Fenugreek (Trigonella foenum-graecum L.) is a self-pollinated leguminous crop belonging to the Fabaceae family. It is a multipurpose crop used as herb, spice, vegetable and forage. It is a traditional medicinal plant in India attributed with several nutritional and medicinal properties including antidiabetic and anticancer. We have performed a combined transcriptome assembly from RNA sequencing data derived from leaf, stem and root tissues. Around 209,831 transcripts were deciphered from the assembly of 92% completeness and an N50 of 1382 bases. Whilst secondary metabolites of medicinal value, such as trigonelline, diosgenin, 4-hydroxyisoleucine and quercetin, are distributed in several tissues, we report transcripts that bear sequence signatures of enzymes involved in the biosynthesis of such metabolites and are highly expressed in leaves, stem and roots. One of the antidiabetic alkaloid, trigonelline and its biosynthesising enzyme, is highly abundant in leaves. These findings are of value to nutritional and the pharmaceutical industry.
(© 2022. The Author(s).)
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المشرفين على المادة: 0 (Hypoglycemic Agents)
0 (Plant Extracts)
K49P2K8WLX (Diosgenin)
تواريخ الأحداث: Date Created: 20220808 Date Completed: 20220810 Latest Revision: 20221019
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC9359999
DOI: 10.1038/s41598-022-17779-8
PMID: 35941189
قاعدة البيانات: MEDLINE
الوصف
تدمد:2045-2322
DOI:10.1038/s41598-022-17779-8