دورية أكاديمية
Association of shivering threshold time with body composition and brown adipose tissue in young adults.
| العنوان: | Association of shivering threshold time with body composition and brown adipose tissue in young adults. |
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| المؤلفون: | Sardjoe Mishre ASD; Department of Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, the Netherlands; Department of Radiology, C.J. Gorter MRI Center, Leiden, the Netherlands. Electronic address: A.S.D.Sardjoe_Mishre@lumc.nl., Martinez-Tellez B; Department of Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, the Netherlands; Department of Physical Education and Sport, Faculty of Sport Sciences, PROFITH 'PROmoting FITness and Health Through Physical Activity' Research Group, Sport and Health University Research Institute(iMUDS), University of Granada, Granada, Spain; Department of Education, Faculty of Education Sciences and SPORT Research Group(CTS-1024), CERNEP Research Center, University of Almería, Almería, Spain. Electronic address: B.Martinez-Tellez@lumc.nl., Acosta FM; Department of Physical Education and Sport, Faculty of Sport Sciences, PROFITH 'PROmoting FITness and Health Through Physical Activity' Research Group, Sport and Health University Research Institute(iMUDS), University of Granada, Granada, Spain; Turku PET Centre, University of Turku, Turku, Finland; Turk PET Centre, Turku University Hospital, Turku, Finland., Sanchez-Delgado G; Department of Physical Education and Sport, Faculty of Sport Sciences, PROFITH 'PROmoting FITness and Health Through Physical Activity' Research Group, Sport and Health University Research Institute(iMUDS), University of Granada, Granada, Spain; Pennington Biomedical Research Center, Baton Rouge, LA, USA., Straat ME; Department of Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, the Netherlands., Webb AG; Department of Radiology, C.J. Gorter MRI Center, Leiden, the Netherlands., Kan HE; Department of Radiology, C.J. Gorter MRI Center, Leiden, the Netherlands., Rensen PCN; Department of Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, the Netherlands., Ruiz JR; Department of Physical Education and Sport, Faculty of Sport Sciences, PROFITH 'PROmoting FITness and Health Through Physical Activity' Research Group, Sport and Health University Research Institute(iMUDS), University of Granada, Granada, Spain; Instituto de Investigación Biosanitaria, Ibs.Granada, Granada, Spain. Electronic address: ruizj@ugr.es. |
| المصدر: | Journal of thermal biology [J Therm Biol] 2022 Aug; Vol. 108, pp. 103277. Date of Electronic Publication: 2022 Jun 07. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Pergamon Press Country of Publication: England NLM ID: 7600115 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0306-4565 (Print) Linking ISSN: 03064565 NLM ISO Abbreviation: J Therm Biol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Oxford, New York, Pergamon Press. |
| مواضيع طبية MeSH: | Adipose Tissue, Brown* , Fluorodeoxyglucose F18*, Adult ; Body Composition ; Cold Temperature ; Female ; Humans ; Male ; Positron Emission Tomography Computed Tomography ; Shivering ; Young Adult |
| مستخلص: | Purpose: Brown adipose tissue (BAT) increases metabolic heat production in response to cold exposure. Body size and composition are involved in the human cold response, yet the influence of BAT herein have not fully been explored. Here, we aimed to study the association of the cold-induced shivering threshold time with body composition, BAT, the perception of shivering and skin temperature in young adults. Methods: 110 young healthy adults (81 females; age = 21.7 ± 2.1 years, BMI = 24.2 ± 4.3 kg/m 2 ) underwent 2 h of individualized cooling, followed by the quantification of BAT using a 18 F-fluorodeoxyglucose ([ 18 F]FDG) positron emission tomography-computed tomography (PET-CT) scan. Body mass index (BMI), lean mass, fat mass and body surface area (BSA) were also measured. Shivering threshold time was defined as the time until shivering occurred using an individualized cooling protocol. Results: The shivering threshold time was on average 116.1 min for males and 125.8 min for females, and was positively associated to BMI (β = 3.106; R 2 = 0.141; p = 0.001), lean mass (β = 2.295; R 2 = 0.128; p = 0.001) and fat mass (β = 1.492; R 2 = 0.121; p = 0.001) in females, but not in males (all p ≥ 0.409). The shivering threshold time was positively associated with BSA in males (p = 0.047) and females (p = 0.001), but it was not associated with BAT volume or [ 18 F]FDG uptake nor with the perception of shivering and skin temperature perception in both sexes. Conclusion: The shivering threshold time is positively associated with whole-body adiposity and lean mass in females, but not in males. The shivering threshold time was positively associated with BSA, but no association was observed with BAT nor with the perception of shivering or skin temperature. Future research should consider the influence of body composition when applying cooling protocols among individuals with different phenotypical features. (Copyright © 2022 The Authors. Published by Elsevier Ltd.. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Cold perception; Shivering time; Thermogenesis; brown fat |
| المشرفين على المادة: | 0Z5B2CJX4D (Fluorodeoxyglucose F18) |
| تواريخ الأحداث: | Date Created: 20220828 Date Completed: 20220830 Latest Revision: 20220830 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1016/j.jtherbio.2022.103277 |
| PMID: | 36031206 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0306-4565 |
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| DOI: | 10.1016/j.jtherbio.2022.103277 |