دورية أكاديمية
Determinants of the psychomotor development delay in children aged 12 to 59 months infected with HIV in Yaounde, Cameroon.
| العنوان: | Determinants of the psychomotor development delay in children aged 12 to 59 months infected with HIV in Yaounde, Cameroon. |
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| المؤلفون: | Kalla GCM; Faculty of Medicine and Biomedical Science, University of Yaounde I, Yaounde, Cameroon., Dongmo ULT; Faculty of Medicine and Biomedical Science, University of Yaounde I, Yaounde, Cameroon., Assob JCN; Faculty of Health Science, University of Buea, Buea, Cameroon., Noubi NK; Faculty of Medicine and Biomedical Science, University of Yaounde I, Yaounde, Cameroon., Mbopi-Keou FX; Faculty of Medicine and Biomedical Science, University of Yaounde I, Yaounde, Cameroon.; The Institute for the Development of Africa (The-IDA), Yaounde, Cameroon.; Information Communication Technology University (ICT-U), Yaounde, Cameroon., Monebenimp F; Faculty of Medicine and Biomedical Science, University of Yaounde I, Yaounde, Cameroon. |
| المصدر: | The Pan African medical journal [Pan Afr Med J] 2022 Jun 10; Vol. 42, pp. 114. Date of Electronic Publication: 2022 Jun 10 (Print Publication: 2022). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: African Field Epidemiology Network Country of Publication: Uganda NLM ID: 101517926 Publication Model: eCollection Cited Medium: Internet ISSN: 1937-8688 (Electronic) NLM ISO Abbreviation: Pan Afr Med J Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Kampala, Uganda : African Field Epidemiology Network |
| مواضيع طبية MeSH: | HIV Infections*, Cameroon ; Child ; Child, Preschool ; Cross-Sectional Studies ; Humans ; Psychomotor Disorders ; Viral Load |
| مستخلص: | Introduction: children infected with HIV are at increased risk of impaired neurodevelopmental, due to several environmental factors. Methods: we conducted a cross-sectional analytical study on HIV-infected children aged 12 to 59 months, followed up in five hospitals in Yaounde, Cameroon. Sociodemographic, clinical, and biological variables as well as the antecedents were collected. Data analysis was performed using Statistical Package for the Social Sciences (SPSS) version 25 software. The Denver test was used to assess the psychomotor development of these children. Global psychomotor delay, defined as a global development quotient of less than 70 with an alteration in at least two of the four domains of the test, was retained as the primary endpoint. The significance threshold was set at 5%. Results: one hundred and eighty-one children were included in the study. The sex ratio was 0.6. The age range 48-59 months was the most represented. None of these children had a known chronic pathology other than HIV infection. The proportion of global psychomotor delay was 11.04%, with language (16%) and fine motor skills (16%) being the most affected domains of psychomotor development. The independent factors significantly associated with global psychomotor delay were birth weight below 2500 grams (OR= 17.61 [1.76-181.39], p= 0.022), growth retardation (OR= 17.64 [1.63-190.24], p= 0.018) and elevated viral load (OR= 22.75 [2.78-186.02], p= 0.004). Conclusion: psychomotor delay affects about one out of ten children living with HIV. Its occurrence is linked to various factors that must be taken into account in the development of public health policies in connection with the management of HIV infection in children. Competing Interests: The authors declare no competing interests. (Copyright: Ginette Claude Mireille Kalla et al.) |
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| فهرسة مساهمة: | Keywords: Cameroon; HIV; Psychomotor delay; Yaounde; children |
| تواريخ الأحداث: | Date Created: 20220829 Date Completed: 20220830 Latest Revision: 20220830 |
| رمز التحديث: | 20240829 |
| مُعرف محوري في PubMed: | PMC9392003 |
| DOI: | 10.11604/pamj.2022.42.114.33195 |
| PMID: | 36034046 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1937-8688 |
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| DOI: | 10.11604/pamj.2022.42.114.33195 |