دورية أكاديمية
Management of acute sickle cell priapism in an African (Togo) pediatric department includes conservative measures and intracavernous epinephrine which is safe and efficacious.
| العنوان: | Management of acute sickle cell priapism in an African (Togo) pediatric department includes conservative measures and intracavernous epinephrine which is safe and efficacious. |
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| المؤلفون: | Guedenon KM; Department of Pediatrics CHU Sylvanus Olympio, University of Lomé Togo., Fiawoo M; Department of Pediatrics CHU Sylvanus Olympio, University of Lomé Togo., Akolly DAE; Department of Pediatrics CHU Sylvanus Olympio, University of Lomé Togo., Akpako E; University of Maryland Medical Systems/Midtown Campus Baltimore Maryland USA., Esso B; Department of Pediatrics CHU Sylvanus Olympio, University of Lomé Togo., Dossou FC; Department of Pediatrics CHU Sylvanus Olympio, University of Lomé Togo., Gbadoe AD; Department of Pediatrics CHU Sylvanus Olympio, University of Lomé Togo. |
| المصدر: | EJHaem [EJHaem] 2022 Apr 26; Vol. 3 (3), pp. 628-635. Date of Electronic Publication: 2022 Apr 26 (Print Publication: 2022). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101761942 Publication Model: eCollection Cited Medium: Internet ISSN: 2688-6146 (Electronic) Linking ISSN: 26886146 NLM ISO Abbreviation: EJHaem Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: [Hoboken, New Jersey] : John Wiley & Sons, Inc., [2020]- |
| مستخلص: | Priapism is a well-known urologic complication of sickle cell anemia. This study describes the results of a protocol for the treatment of acute priapism by intracavernous injection of epinephrine due to unavailability of etilefrine. A descriptive cross-sectional study of 18 cases of acute priapism in sickle cell patients treated in the pediatric department of the Sylvanus Olympio CHU from January 1 to December 31, 2020. The average age was 21.7 ± 7.7 years, the youngest patient was 8 and the oldest was 32 years old. Students represented 61.1% of the patients. The hemoglobin profiles were homozygous SS ( n = 14) and double heterozygous SC ( n = 4). Most of the crisis (83.3%) occurred at night. Most of the patients (66.7%) came to the hospital before the sixth hour of crisis, one patient came by the 48th hour. Walking was the most self-relief method tried by patients (67%). It was followed by a cold penile bath, attempted urination, body bath, and lastly lukewarm bath. Fourteen patients had a history of chronic intermittent priapism. The average pain intensity was 9.5 ± 0.9 with restlessness (33.3%) and crying (33.3%). Fifteen patients were treated upon admission with an intracavernosal injection of epinephrine, and three patients were first drained. Thirteen patients achieved remission immediately, while five patients required a second injection and only one had to be drained before remission. Tolerance was good. One patient had a borderline systolic blood pressure. One erectile weakness case was noticed and no cases of sexual impotence. Epinephrine by intracavernosal injection is an efficient treatment for acute priapism in sickle cell patients. Epinephrine, which has a good tolerance in pediatric and young adult patients, should be used in lieu of etilefrine due to its unavailability in areas where it is unavailable. Competing Interests: There is no conflict of interest for the authors of this research. (© 2022 The Authors. eJHaem published by British Society for Haematology and John Wiley & Sons Ltd.) |
| References: | Hemoglobin. 2012;36(2):177-82. (PMID: 22273484) BJU Int. 2000 Mar;85(4):493-5. (PMID: 10691831) Blood. 2006 Mar 15;107(6):2279-85. (PMID: 16291595) J Sex Med. 2010 Jan;7(1 Pt 2):476-500. (PMID: 20092449) Pan Afr Med J. 2014 Apr 15;17:286. (PMID: 25317234) Chirurgie. 1997 Jan;121(9-10):648-52. (PMID: 9138325) BJU Int. 2002 Dec;90(9):898-902. (PMID: 12460353) J Urol. 1986 Jan;135(1):142-7. (PMID: 3941454) Hemoglobin. 2001 Nov;25(4):355-61. (PMID: 11791867) Arch Intern Med. 1980 Nov;140(11):1434-7. (PMID: 6159833) Med Trop (Mars). 2010 Dec;70(5-6):475-8. (PMID: 21520650) West Afr J Med. 2009 Jul-Aug;28(4):234-9. (PMID: 20425738) Prog Urol. 2014 Jan;24(1):57-61. (PMID: 24365630) Eur Urol. 2014 Feb;65(2):480-9. (PMID: 24314827) J Androl. 2011 Jul-Aug;32(4):375-82. (PMID: 21127308) Niger J Clin Pract. 2016 Mar-Apr;19(2):207-11. (PMID: 26856282) J Pediatr Urol. 2014 Feb;10(1):11-24. (PMID: 24135215) Br J Haematol. 2005 Jan;128(2):266-72. (PMID: 15638863) Bull Soc Pathol Exot. 2007 Aug;100(3):179-81. (PMID: 17824310) Blood. 2015 Jun 4;125(23):3551-8. (PMID: 25810489) Urology. 2016 Mar;89:118-22. (PMID: 26674747) J Urol. 1977 Apr;117(4):455-8. (PMID: 15137) Ann Trop Paediatr. 1981 Sep;1(3):143-7. (PMID: 6185061) Blood. 2000 Jan 1;95(1):78-82. (PMID: 10607688) Med Trop (Mars). 2000;60(1):53-6. (PMID: 10989788) Acta Haematol. 1985;73(3):181-2. (PMID: 2412383) East Afr Med J. 2003 Oct;80(10):518-24. (PMID: 15250624) Med Trop (Mars). 2000;60(1):70-4. (PMID: 10989793) J Urol. 2003 Oct;170(4 Pt 1):1318-24. (PMID: 14501756) J Urol. 2013 Oct;190(4):1275-80. (PMID: 23583536) Int Surg. 2015 Mar;100(3):552-7. (PMID: 25785343) |
| فهرسة مساهمة: | Keywords: epinephrine; priapism; sickle cell (patient) |
| تواريخ الأحداث: | Date Created: 20220902 Latest Revision: 20220907 |
| رمز التحديث: | 20221213 |
| مُعرف محوري في PubMed: | PMC9422026 |
| DOI: | 10.1002/jha2.440 |
| PMID: | 36051024 |
| قاعدة البيانات: | MEDLINE |
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