دورية أكاديمية

The relationship between serum 25-hydroxy vitamin D and arteriogenic erectile dysfunction.

التفاصيل البيبلوغرافية
العنوان: The relationship between serum 25-hydroxy vitamin D and arteriogenic erectile dysfunction.
المؤلفون: Wu X; Department of Urology, the First Affiliated Hospital of Anhui Medical University, Anhui, China., Zhang Y; Department of Urology, the First Affiliated Hospital of Anhui Medical University, Anhui, China., Zhang W; Department of Urology, the First Affiliated Hospital of Anhui Medical University, Anhui, China., Liu G; Department of Urology, the First Affiliated Hospital of Anhui Medical University, Anhui, China., Jiang H; Department of Urology, Peking University First Hospital, Beijing, China., Huang H; Department of Urology, The first Affiliated Hospital of Wannan Medical College, Wuhu, China., Zhang X; Department of Urology, the First Affiliated Hospital of Anhui Medical University, Anhui, China.
المصدر: Andrologia [Andrologia] 2022 Dec; Vol. 54 (11), pp. e14568. Date of Electronic Publication: 2022 Aug 29.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Blackwell Pub Country of Publication: Germany NLM ID: 0423506 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-0272 (Electronic) Linking ISSN: 03034569 NLM ISO Abbreviation: Andrologia Subsets: MEDLINE
أسماء مطبوعة: Publication: : Berlin : Blackwell Pub.
Original Publication: Berlin, Grosse
مواضيع طبية MeSH: Erectile Dysfunction* , Impotence, Vasculogenic*/diagnostic imaging , Impotence, Vasculogenic*/etiology, Male ; Humans ; Penis/diagnostic imaging ; Penile Erection ; Vitamin D ; Calcifediol
مستخلص: This study aimed to assess the relationship between 25(OH) levels and erectile dysfunction (ED), particularly arteriogenic ED (A-ED). From September 2020 to January 2022, 150 patients diagnosed with ED by the International Index of Erectile Function-5 (IIEF-5) questionnaire were included. All patients were classified as organic ED and psychological ED by nocturnal penile tumescence and rigidity (NPTR) examination. Organic ED patients were divided into A-ED and NA-ED by penile doppler ultrasound (PDU) examination. Finally, 150 patients complaining of ED were enrolled in our study. 25(OH)D levels were significantly lower in patients with organic ED (18.24 ± 6.04 ng/ml) than in patients with psychogenic ED (20.90 ± 8.79 ng/ml) (p = 0.032). In A-ED and NA-ED, the mean of peak systolic flow velocity (PSV) values was 18.94 ± 5.28 cm/s and 51.57 ± 15.42 cm/s (p < 0.001), and the mean of 25(OH)D was 15.66 ± 5.86 ng/ml and 20.48 ± 5.90 ng/ml, respectively (p < 0.001). The results showed that 25(OH)D levels were positively correlated with IIEF-5 scores and the PSV values in A-ED patients. The 25(OH)D cut-off value differentiating between A-ED and NA-ED was 15.05 ng/ml. Low 25(OH)D levels may be an independent risk factor for ED, especially A-ED. ED patients should routinely undergo serum 25(OH)D level measurement, and 25(OH)D replacement therapy is necessary for patients with low vitamin D levels.
(© 2022 Wiley-VCH GmbH.)
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معلومات مُعتمدة: 8207061072 National Natural Science Foundation of China
فهرسة مساهمة: Keywords: endothelial dysfunction; erectile dysfunction; nocturnal penile tumescence and rigidity; penile Doppler ultrasound; serum 25-hydroxy vitamin D
المشرفين على المادة: A288AR3C9H (25-hydroxyvitamin D)
1406-16-2 (Vitamin D)
P6YZ13C99Q (Calcifediol)
تواريخ الأحداث: Date Created: 20220902 Date Completed: 20221202 Latest Revision: 20221202
رمز التحديث: 20221213
DOI: 10.1111/and.14568
PMID: 36054412
قاعدة البيانات: MEDLINE
الوصف
تدمد:1439-0272
DOI:10.1111/and.14568