دورية أكاديمية

Endometrial carcinoma in asymptomatic post-menopausal women with a thickened endometrium and its influencing factors - A cross-sectional study.

التفاصيل البيبلوغرافية
العنوان: Endometrial carcinoma in asymptomatic post-menopausal women with a thickened endometrium and its influencing factors - A cross-sectional study.
المؤلفون: Pegu B; Department of Obstetrics and Gynecology, JIPMER, Puducherry, India., Saranya TS; Department of Obstetrics and Gynecology, JIPMER, Puducherry, India., Murugesan R; Department of Biostatistics, JIPMER, Puducherry, India.
المصدر: Journal of family medicine and primary care [J Family Med Prim Care] 2022 Jun; Vol. 11 (6), pp. 2956-2960. Date of Electronic Publication: 2022 Jun 30.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Medknow Country of Publication: India NLM ID: 101610082 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2249-4863 (Print) Linking ISSN: 22494863 NLM ISO Abbreviation: J Family Med Prim Care Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Mumbai : Medknow
مستخلص: Background: A thickened endometrium upon trans-vaginal ultrasound in asymptomatic post-menopausal women always poses a clinical dilemma.
Objectives: To investigate the frequency of endometrial malignancies by histopathological examination and identify the associated factors influencing the thickened endometrium in asymptomatic post-menopausal women.
Methods: In trans-vaginal ultrasonography, we enrolled 72 asymptomatic post-menopausal women with a thickened endometrium (>5 mm). Dilatation and curettage were performed for all cases, and the specimen was sent for histopathological examination. According to the data distribution, all the continuous variables were stated as mean ± standard deviation/median (inter-quartile range), categorical variables were expressed in frequency, and percentage will be compared using the Chi-square test/Fisher exact test.
Results: In our study, most of the women were multipara. The age of post-menopausal women ranged from 46 to 68 years, and the mean duration of menopause was 8.10. The most common histological findings were benign in 72.22% of the cases. We identified pre-malignant and malignant lesions of the endometrium in 18.05% and 9.72% of the cases, respectively. To predict the condition of the lesion, we noticed no definite cut-off value of endometrial thickness to indicate the state of the lesion. We observed that none of the patient's characteristics showed a significant difference with a thickened endometrium.
Conclusion: We observed an increased frequency of endometrial pathology irrespective of the presence or absence of risk factors. The result of this study is justified enough for the need of further evaluation of a thickened endometrium in asymptomatic post-menopausal women.
Competing Interests: There are no conflicts of interest.
(Copyright: © 2022 Journal of Family Medicine and Primary Care.)
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فهرسة مساهمة: Keywords: Asymptomatic endometrial thickening; dilatation and curettage; endometrial carcinoma; post-menopausal women; trans-vaginal ultrasonography
تواريخ الأحداث: Date Created: 20220919 Latest Revision: 20220920
رمز التحديث: 20240829
مُعرف محوري في PubMed: PMC9480687
DOI: 10.4103/jfmpc.jfmpc_2347_21
PMID: 36119244
قاعدة البيانات: MEDLINE
الوصف
تدمد:2249-4863
DOI:10.4103/jfmpc.jfmpc_2347_21