دورية أكاديمية
Slit-skin smear for the classification of leprosy; are we wasting time and resource?
| العنوان: | Slit-skin smear for the classification of leprosy; are we wasting time and resource? |
|---|---|
| المؤلفون: | Demsiss W; College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia. wonde1980@gmail.com., Van Henten S; Institute of Tropical Medicine, Antwerp, Belgium., Takarinda KC; Center for Operational Research, International Union Against Tuberculosis and Lung Disease, Paris, France., Kamau EM; UNICEF/UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (TDR), World Health Organization, Geneva, Switzerland., Abdela SG; College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia. |
| المصدر: | Journal of infection in developing countries [J Infect Dev Ctries] 2022 Aug 31; Vol. 16 (8.1), pp. 3S-7S. Date of Electronic Publication: 2022 Aug 31. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Open Learning on Enteric Pathogens Country of Publication: Italy NLM ID: 101305410 Publication Model: Electronic Cited Medium: Internet ISSN: 1972-2680 (Electronic) Linking ISSN: 19722680 NLM ISO Abbreviation: J Infect Dev Ctries Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: [Italy?] : Open Learning on Enteric Pathogens |
| مواضيع طبية MeSH: | Leprosy*/diagnosis , Mycobacterium leprae*, Cross-Sectional Studies ; Hospitals, General ; Humans ; Skin/pathology |
| مستخلص: | Introduction: Leprosy is a chronic neglected tropical disease, classified into two groups: multibacillary (MB) and paucibacillary (PB) leprosy based on the number of skin lesions and nerve involvement. A positive skin slit smear (SSS) result automatically puts a patient in the MB category. Although guidelines do not recommend routine use of SSS for classification and diagnosis of leprosy, it is performed for most patients in Ethiopia. However, the added value of performing SSS for the classification of leprosy on top of clinical classification is unclear. Methodology: A cross sectional study was done using routine laboratory and clinical data from September 2018 to January 2020 at Boru Meda General Hospital, Ethiopia. All newly diagnosed leprosy cases were included. Descriptive statistics were performed to calculate frequencies and proportions. Results: We included 183 new leprosy patients in our study, of which 166/183 (90.7%) were MB patients and 17/183 (9.3%) were PB patients. All clinical PB cases and 150/166 (90.4%) clinical MB patients had SSS done. All PB patients had negative SSS result and 68 (45.3%) clinical MB patients had a positive result. Based on the SSS, no patient with a clinical classification of PB was reclassified to MB. Conclusions: SSS microscopy was performed routinely for all leprosy cases without changing the classification and management of patients in Boru Meda Hospital. Therefore, we recommend restricted and rational use of the SSS for PB cases in which SSS could change management. Competing Interests: No Conflict of Interest is declared (Copyright (c) 2022 Wondmagegn Demsiss, Saskia van Henten, Kudakwashe Collin Takarinda, Edward Mberu Kamau, Seid Getahun Abdela.) |
| معلومات مُعتمدة: | 001 International WHO_ World Health Organization |
| فهرسة مساهمة: | Keywords: Ethiopia; Hansen’s disease; SORT-IT; operational research; skin snip |
| تواريخ الأحداث: | Date Created: 20220926 Date Completed: 20220928 Latest Revision: 20221108 |
| رمز التحديث: | 20240628 |
| DOI: | 10.3855/jidc.15992 |
| PMID: | 36156495 |
| قاعدة البيانات: | MEDLINE |
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