دورية أكاديمية
أعرض في EDS

Evaluation of gastroesophageal reflux disease and hiatal hernia as risk factors for lobectomy complications.

التفاصيل البيبلوغرافية
العنوان: Evaluation of gastroesophageal reflux disease and hiatal hernia as risk factors for lobectomy complications.
المؤلفون: Kaminski MF; Division of Thoracic Surgery, Department of Surgery, Yale School of Medicine, New Haven, Conn., Ermer T; Division of Thoracic Surgery, Department of Surgery, Yale School of Medicine, New Haven, Conn.; London School of Hygiene & Tropical Medicine, University of London, London, United Kingdom., Canavan M; Cancer Outcomes, Public Policy and Effectiveness Research Center, Yale School of Medicine, New Haven, Conn., Li AX; Division of Thoracic Surgery, Department of Surgery, Yale School of Medicine, New Haven, Conn., Maduka RC; Division of Thoracic Surgery, Department of Surgery, Yale School of Medicine, New Haven, Conn., Zhan P; Division of Thoracic Surgery, Department of Surgery, Yale School of Medicine, New Haven, Conn., Boffa DJ; Division of Thoracic Surgery, Department of Surgery, Yale School of Medicine, New Haven, Conn., Case MD; Division of Interventional Radiology, Department of Radiology & Biomedical Imaging, Yale School of Medicine, New Haven, Conn.
المصدر: JTCVS open [JTCVS Open] 2022 Jun 03; Vol. 11, pp. 327-345. Date of Electronic Publication: 2022 Jun 03 (Print Publication: 2022).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Ltd Country of Publication: Netherlands NLM ID: 101768541 Publication Model: eCollection Cited Medium: Internet ISSN: 2666-2736 (Electronic) Linking ISSN: 26662736 NLM ISO Abbreviation: JTCVS Open Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: [Amsterdam, The Netherlands] : Elsevier Ltd., [2020]-
مستخلص: Objective: Up to 40% of lobectomies are complicated by adverse events. Gastroesophageal reflux disease (GERD) and hiatal hernia have been associated with morbidity across a range of clinical scenarios, yet their relation to recovery from pulmonary resection is understudied. We evaluated GERD and hiatal hernia as predictors of complications after lobectomy for lung cancer.
Methods: Lobectomy patients at Yale-New Haven Hospital between January 2014 and April 2021 were evaluated for predictors of 30-day postoperative complications, pneumonia, atrial arrhythmia, readmission, and mortality. Multivariable regression models included sociodemographic characteristics, body mass index, surgical approach, cardiopulmonary comorbidities, hiatal hernia, GERD, and preoperative acid-suppressive therapy as predictors.
Results: Overall, 824 patients underwent lobectomy, including 50.5% with a hiatal hernia and 38.7% with GERD. The median age was 68 [interquartile range, 61-74] years, and the majority were female (58.4%). At least 1 postoperative complication developed in 39.6% of patients, including atrial arrhythmia (11.7%) and pneumonia (4.1%). Male sex (odds ratio [OR], 1.51; 95% confidence interval [CI], 1.11-2.06, P  = .01), age ≥70 years (OR, 1.55; 95% CI, 1.13-2.11, P  = .01), hiatal hernia (OR, 1.40; 95% CI, 1.03-1.90, P  = .03), and intraoperative packed red blood cells (OR, 4.80; 95% CI, 1.51-15.20, P  = .01) were significant risk factors for developing at least 1 postoperative complication. Hiatal hernia was also a significant predictor of atrial arrhythmia (OR, 1.64; 95% CI, 1.02-2.62, P  = .04) but was not associated with other adverse events.
Conclusions: Our findings indicate that hiatal hernia may be a novel risk factor for complications, especially atrial arrhythmia, following lobectomy that should be considered in the preoperative evaluation of lung cancer patients.
(© 2022 The Author(s).)
References: J Cardiothorac Surg. 2012 Jan 10;7:4. (PMID: 22233837)
Ann Thorac Surg. 2017 May;103(5):1566-1572. (PMID: 28215423)
Eur Respir J. 2012 Feb;39(2):344-51. (PMID: 21737563)
BMJ. 2014 Oct 23;349:g6154. (PMID: 25341679)
Eur Respir J. 2016 Sep;48(3):833-42. (PMID: 27174889)
Surg Innov. 2017 Apr;24(2):122-132. (PMID: 28128014)
Pol J Radiol. 2021 Jan 08;86:e1-e3. (PMID: 33708268)
J Clin Gastroenterol. 1984 Oct;6(5):467-70. (PMID: 6501834)
Anaesthesia. 2016 Dec;71(12):1424-1430. (PMID: 27666330)
World J Gastroenterol. 2014 Jul 28;20(28):9592-9. (PMID: 25071357)
Am J Respir Crit Care Med. 2006 May 15;173(10):1161-9. (PMID: 16474029)
Ann Thorac Surg. 2010 Aug;90(2):368-74. (PMID: 20667313)
J Thorac Cardiovasc Surg. 2013 May;145(5):1312-8. (PMID: 23142119)
Nat Rev Cardiol. 2020 Aug;17(8):474-502. (PMID: 32231332)
Neurogastroenterol Motil. 2015 Jul;27(7):963-70. (PMID: 25930019)
J Thorac Cardiovasc Surg. 2007 Mar;133(3):775-9. (PMID: 17320583)
Interact Cardiovasc Thorac Surg. 2017 Feb 1;24(2):260-264. (PMID: 27803121)
Respir Med. 2012 Oct;106(10):1463-71. (PMID: 22862997)
Surgery. 2019 Aug;166(2):211-217. (PMID: 31202473)
Radiol Clin North Am. 2012 Sep;50(5):863-76. (PMID: 22974775)
J Thorac Dis. 2017 May;9(5):1289-1294. (PMID: 28616280)
Gastroenterology. 2020 Apr;158(5):1250-1261.e2. (PMID: 31866243)
Eur J Cardiothorac Surg. 2014 Apr;45(4):652-9; discussion 659. (PMID: 24062351)
Am J Surg. 2010 Apr;199(4):558-61. (PMID: 20359574)
Ann Thorac Surg. 2016 Apr;101(4):1379-86; discussion 1386-7. (PMID: 26785936)
Asian Pac J Cancer Prev. 2014;15(7):3071-4. (PMID: 24815449)
Ther Adv Drug Saf. 2018 Nov 19;10:2042098618809927. (PMID: 31019676)
CMAJ. 2011 Feb 22;183(3):310-9. (PMID: 21173070)
J Korean Med Sci. 2011 Aug;26(8):979-84. (PMID: 21860545)
J Atr Fibrillation. 2013 Aug 31;6(2):894. (PMID: 28496881)
World J Surg. 2020 Nov;44(11):3952-3959. (PMID: 32681318)
J Thorac Cardiovasc Surg. 2011 Jul;142(1):47-52.e3. (PMID: 21683838)
PLoS One. 2017 Aug 24;12(8):e0183808. (PMID: 28837700)
CA Cancer J Clin. 2016 Jan-Feb;66(1):7-30. (PMID: 26742998)
Ann Thorac Surg. 2014 Jan;97(1):236-42; discussion 242-4. (PMID: 24090577)
Am J Cardiol. 2008 Nov 1;102(9):1207-11. (PMID: 18940293)
Am Surg. 2018 Jun 1;84(6):978-982. (PMID: 29981634)
J Clin Gastroenterol. 2007 Oct;41(9):814-8. (PMID: 17881926)
Respir Med. 2015 Oct;109(10):1340-6. (PMID: 26209227)
Surg Today. 2000;30(10):879-85. (PMID: 11059726)
Eur Surg. 2017;49(5):210-217. (PMID: 29104588)
AJR Am J Roentgenol. 1977 Apr;128(4):549-61. (PMID: 403780)
J Gastrointest Surg. 2016 Jan;20(1):104-10; discussion 110. (PMID: 26403715)
Ann Thorac Surg. 2018 Sep;106(3):902-908. (PMID: 29704479)
Ann Epidemiol. 2001 Oct;11(7):477-83. (PMID: 11557179)
Ann Thorac Surg. 2012 Feb;93(2):372-9. (PMID: 21945225)
Europace. 2017 Jan;19(1):16-20. (PMID: 27247004)
معلومات مُعتمدة: T32 CA233414 United States CA NCI NIH HHS; T35 DK104689 United States DK NIDDK NIH HHS; UL1 TR001863 United States TR NCATS NIH HHS
فهرسة مساهمة: Keywords: BMI, body mass index; CI, confidence interval; CT, computed tomography; GERD; GERD, gastroesophageal reflux disease; OR, odds ratio; RBC, red blood cell; atrial arrhythmia; hiatal hernia; lobectomy; lung cancer; postoperative complications
تواريخ الأحداث: Date Created: 20220929 Latest Revision: 20240517
رمز التحديث: 20240517
مُعرف محوري في PubMed: PMC9510864
DOI: 10.1016/j.xjon.2022.05.017
PMID: 36172441
قاعدة البيانات: MEDLINE
الوصف
تدمد:2666-2736
DOI:10.1016/j.xjon.2022.05.017