دورية أكاديمية

Endovascular treatment of wide-necked intracranial aneurysms using the Nautilus Intrasaccular System: initial case series of 41 patients at a single center.

التفاصيل البيبلوغرافية
العنوان: Endovascular treatment of wide-necked intracranial aneurysms using the Nautilus Intrasaccular System: initial case series of 41 patients at a single center.
المؤلفون: Sirakov A; Radiology Department, University Hospital St Ivan Rilski, Sofia, Bulgaria., Bhogal P; Interventional Neuroradiology, The Royal Hospital, London, UK., Sirakova K; Radiology Department, University Hospital Alexandrovska, Sofia, Bulgaria., Penkov M; Radiology Department, University Hospital St Ivan Rilski, Sofia, Bulgaria., Minkin K; Neurosurgery Department, University Hospital St Ivan Rilski, Sofia, Bulgaria., Ninov K; Neurosurgery Department, University Hospital St Ivan Rilski, Sofia, Bulgaria., Hristov H; Neurosurgery Department, University Hospital St Ivan Rilski, Sofia, Bulgaria., Hadzhiyanev A; Neurosurgery Department, University Hospital St Ivan Rilski, Sofia, Bulgaria., Karakostov V; Neurosurgery Department, University Hospital St Ivan Rilski, Sofia, Bulgaria., Sirakov S; Radiology Department, University Hospital St Ivan Rilski, Sofia, Bulgaria ssirakov@bsunivers.com.
المصدر: Journal of neurointerventional surgery [J Neurointerv Surg] 2023 Oct; Vol. 15 (10), pp. 989-994. Date of Electronic Publication: 2022 Oct 19.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: BMJ Publishing Group Country of Publication: England NLM ID: 101517079 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1759-8486 (Electronic) Linking ISSN: 17598478 NLM ISO Abbreviation: J Neurointerv Surg Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BMJ Publishing Group, c2009-
مواضيع طبية MeSH: Intracranial Aneurysm*/diagnostic imaging , Intracranial Aneurysm*/surgery , Nautilus* , Embolization, Therapeutic*/adverse effects , Embolization, Therapeutic*/methods , Endovascular Procedures*/adverse effects , Endovascular Procedures*/methods , Aneurysm, Ruptured*/diagnostic imaging , Aneurysm, Ruptured*/surgery, Humans ; Animals ; Adult ; Middle Aged ; Aged ; Aged, 80 and over ; Treatment Outcome ; Stents ; Retrospective Studies ; Cerebral Angiography
مستخلص: Background: Endovascular treatment of intracranial wide-necked and bifurcation aneurysms (WNBA) is technically challenging. The Nautilus Intrasaccular System is designed to provide a mechanical barrier at the aneurysm neck to support coil embolization. We report the results of a single-center series of patients treated for intracranial aneurysms with the Nautilus.
Methods: Clinical and radiological data were retrospectively collected for all patients treated with the Nautilus for an unruptured or ruptured intracranial aneurysm at our center between March 2021 and March 2022. Clinical outcomes (modified Rankin Scale (mRS) scores), Raymond-Roy angiographic occlusion, recanalization, and complications were measured immediately post-procedure and at 3-6-month follow-up.
Results: A total of 41 patients of mean age 56.7 years (range 37-83 years) were treated with the Nautilus, with 41 saccular aneurysms (18 (43.9%) unruptured and 23 (56.1%) ruptured). The majority of aneurysms (39/41 (95.1%)) were located in the anterior circulation. We experienced no technical complications. One patient had an asymptomatic post-procedural minor stroke related to the procedure. Immediate Class I occlusion was achieved in 30 (73.1%) patients. The rate of all-cause mortality was 7.3% (3/41). One patient was lost to follow-up. At follow-up, 94.5% (35/37) of patients achieved Class I occlusion and 94.5% (35/37) had an mRS score of 0. There were no procedural-related deaths or permanent morbidities at discharge or follow-up.
Conclusion: This study demonstrates good safety and effectiveness using the Nautilus Intrasaccular System to treat both ruptured and unruptured intracranial aneurysms. Larger studies are needed to confirm these findings.
Competing Interests: Competing interests: None declared.
(© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
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فهرسة مساهمة: Keywords: Aneurysm; Angiography; Artery; Brain
تواريخ الأحداث: Date Created: 20221019 Date Completed: 20230918 Latest Revision: 20230923
رمز التحديث: 20230923
مُعرف محوري في PubMed: PMC10511998
DOI: 10.1136/jnis-2022-019295
PMID: 36261278
قاعدة البيانات: MEDLINE
الوصف
تدمد:1759-8486
DOI:10.1136/jnis-2022-019295