دورية أكاديمية

Antibacterial activity of the micro and nanostructures of the optical material tris(8-hydroxyquinoline)aluminum and its application as an antimicrobial coating.

التفاصيل البيبلوغرافية
العنوان: Antibacterial activity of the micro and nanostructures of the optical material tris(8-hydroxyquinoline)aluminum and its application as an antimicrobial coating.
المؤلفون: Saeed A; Department of Physics, Faculty of Science, King Abdulaziz University Jeddah 21589 Saudi Arabia Abdusaeed79@hotmail.com Abdusaeed@tu.edu.ye +966563190832.; Department of Physics, Thamar University Thamar 87246 Yemen.; Center of Nanotechnology, King Abdulaziz University Jeddah 21589 Saudi Arabia., Madkhli AY; Department of Physics, Faculty of Science, Jazan University Jazan 45142 Saudi Arabia., Pashameah RA; Department of Chemistry, Faculty of Applied Science, Umm Al-Qura University Makkah 24230 Saudi Arabia., Bataweel NM; Department of Biological Science, Faculty of Science, King Abdulaziz University Jeddah 21589 Saudi Arabia.; King Fahd Medical Research Centre, King Abdulaziz University Jeddah 21589 Saudi Arabia., Razvi MA; Department of Physics, Faculty of Science, King Abdulaziz University Jeddah 21589 Saudi Arabia Abdusaeed79@hotmail.com Abdusaeed@tu.edu.ye +966563190832., Salah N; Center of Nanotechnology, King Abdulaziz University Jeddah 21589 Saudi Arabia.
المصدر: RSC advances [RSC Adv] 2022 Sep 23; Vol. 12 (42), pp. 27131-27144. Date of Electronic Publication: 2022 Sep 23 (Print Publication: 2022).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101581657 Publication Model: eCollection Cited Medium: Internet ISSN: 2046-2069 (Electronic) Linking ISSN: 20462069 NLM ISO Abbreviation: RSC Adv Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Cambridge [England] : Royal Society of Chemistry, [2011]-
مستخلص: Although tris(8-hydroxyquinoline)aluminum (Alq 3 ), a fluorescent optical organometallic material, is known for its applications in optoelectronics, it has only few and limited applications in the biological field. In this study, the antibacterial activity of Alq 3 micro and nanostructures was investigated. We prepared Alq 3 nanostructures. We prepared nanosized Alq 3 as rice-like structures that assembled into flower shapes with an α-crystal phase. Then, Alq 3 micro and nanostructure antibacterial activities were estimated against seven human pathogenic bacterial strains. Besides, we compared their antibacterial activities with those of standard antibiotics. The minimal inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and IC50 were evaluated. Alq 3 micro and nanostructure antibacterial activity showed considerable values compared to standard antibiotics. Besides, the obtained data revealed that the antibacterial activity of Alq 3 in nanostructures with a new morphology is more than that in microstructures. The antibacterial activity of Alq 3 nanostructures was attributed to their more surface interactions with the bacterial cell wall. The molecules of 8-hydroxyquinoline in the Alq 3 structure could play crucial roles in its antibacterial activity. To apply the achieved results, Alq 3 was incorporated with polystyrene (PS) in a ratio of 2% to fabricate a PS/Alq 3 composite and used to coat glass beakers, which showed inhibition in the bacterial growth reduced to 65% compared with non-coated beakers. The finding of this study showed that Alq 3 could be used as a promising antimicrobial coating.
Competing Interests: There are no conflicts of interest to declare.
(This journal is © The Royal Society of Chemistry.)
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تواريخ الأحداث: Date Created: 20221024 Latest Revision: 20221025
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC9503380
DOI: 10.1039/d2ra04750k
PMID: 36276042
قاعدة البيانات: MEDLINE
الوصف
تدمد:2046-2069
DOI:10.1039/d2ra04750k