دورية أكاديمية
أعرض في EDS

Human African trypanosomiasis cases diagnosed in non-endemic countries (2011-2020).

التفاصيل البيبلوغرافية
العنوان: Human African trypanosomiasis cases diagnosed in non-endemic countries (2011-2020).
المؤلفون: Franco JR; World Health Organization, Control of Neglected Tropical Diseases, Prevention, Treatment and Care, Geneva, Switzerland., Cecchi G; Food and Agriculture Organization of the United Nations, Animal Production and Health Division, Rome, Italy., Priotto G; World Health Organization, Control of Neglected Tropical Diseases, Prevention, Treatment and Care, Geneva, Switzerland., Paone M; Food and Agriculture Organization of the United Nations, Animal Production and Health Division, Rome, Italy., Kadima Ebeja A; World Health Organization, Regional Office for Africa, Brazzaville, Congo., Simarro PP; World Health Organization Consultant., Diarra A; World Health Organization, Regional Office for Africa, Brazzaville, Congo., Sankara D; World Health Organization, Control of Neglected Tropical Diseases, Prevention, Treatment and Care, Geneva, Switzerland., Zhao W; Food and Agriculture Organization of the United Nations, Animal Production and Health Division, Rome, Italy., Dagne DA; World Health Organization, Control of Neglected Tropical Diseases, Prevention, Treatment and Care, Geneva, Switzerland.
المصدر: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2022 Nov 07; Vol. 16 (11), pp. e0010885. Date of Electronic Publication: 2022 Nov 07 (Print Publication: 2022).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE
أسماء مطبوعة: Original Publication: San Francisco, CA : Public Library of Science
مواضيع طبية MeSH: Trypanosomiasis, African*/diagnosis , Trypanosomiasis, African*/epidemiology , Trypanosomiasis, African*/therapy , Tsetse Flies*, Animals ; Humans ; Trypanosoma brucei rhodesiense ; Black People ; Africa, Southern ; Trypanosoma brucei gambiense
مستخلص: Background: Sleeping sickness, or human African trypanosomiasis (HAT), is transmitted by tsetse flies in endemic foci in sub-Saharan Africa. Because of international travel and population movements, cases are also occasionally diagnosed in non-endemic countries.
Methodology/principal Findings: Antitrypanosomal medicines to treat the disease are available gratis through the World Health Organization (WHO) thanks to a public-private partnership, and exclusive distribution of the majority of them enables WHO to gather information on all exported cases. Data collected by WHO are complemented by case reports and scientific publications. During 2011-2020, 49 cases of HAT were diagnosed in 16 non-endemic countries across five continents: 35 cases were caused by Trypanosoma brucei rhodesiense, mainly in tourists visiting wildlife areas in eastern and southern Africa, and 14 cases were due to T. b. gambiense, mainly in African migrants originating from or visiting endemic areas in western and central Africa.
Conclusions/significance: HAT diagnosis in non-endemic countries is rare and can be challenging, but alertness and surveillance must be maintained to contribute to WHO's elimination goals. Early detection is particularly important as it considerably improves the prognosis.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright: © 2022 Franco et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
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معلومات مُعتمدة: 001 International WHO_ World Health Organization
تواريخ الأحداث: Date Created: 20221107 Date Completed: 20221109 Latest Revision: 20221225
رمز التحديث: 20240829
مُعرف محوري في PubMed: PMC9639846
DOI: 10.1371/journal.pntd.0010885
PMID: 36342910
قاعدة البيانات: MEDLINE
الوصف
تدمد:1935-2735
DOI:10.1371/journal.pntd.0010885