دورية أكاديمية
Post-traumatic endophthalmitis prophylaxis: a systematic review and meta-analysis.
| العنوان: | Post-traumatic endophthalmitis prophylaxis: a systematic review and meta-analysis. |
|---|---|
| المؤلفون: | Van Swol JM; College of Medicine, Medical University of South Carolina, Charleston, SC, USA. jmv201@musc.edu., Myers WK; College of Medicine, Medical University of South Carolina, Charleston, SC, USA., Beall JA; Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC, USA., Atteya MM; College of Medicine, Medical University of South Carolina, Charleston, SC, USA., Blice JP; Department of Ophthalmology-Vitreoretinal Surgery, Medical University of South Carolina, Charleston, SC, USA. |
| المصدر: | Journal of ophthalmic inflammation and infection [J Ophthalmic Inflamm Infect] 2022 Nov 18; Vol. 12 (1), pp. 39. Date of Electronic Publication: 2022 Nov 18. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Springer Country of Publication: Germany NLM ID: 101553216 Publication Model: Electronic Cited Medium: Print ISSN: 1869-5760 (Print) Linking ISSN: 18695760 NLM ISO Abbreviation: J Ophthalmic Inflamm Infect Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Berlin : Springer |
| مستخلص: | Purpose: The goal of this study is to determine if certain aspects of endophthalmitis prophylaxis strategies are superior to others. Design: This investigation is a systematic review and meta-analysis. Methods: All studies specifying a type of prophylaxis strategy and resulting rates of endophthalmitis were included. Time course, method of administration, and antibiotic regimen, and confounding factors were collected and included for meta-regression. Results: Time courses greater than 24 h did not significantly improve outcomes. Likewise, intraocular and/or intravenous antibiotic administration methods did not significantly outperform oral administration. No antibiotic regimens performed differently from vancomycin/ ≥ 3 rd generation cephalosporin except for ciprofloxacin monotherapy which yielded significantly worse outcomes. Conclusions: Future antibiotic strategies should strongly consider the risks of antibiotic treatment > 24 h and administration methods other than the oral antibiotic forms. In addition, providers should be wary of using ciprofloxacin monotherapy for endophthalmitis prophylaxis when treating open globe injuries. (© 2022. The Author(s).) |
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| فهرسة مساهمة: | Keywords: Endophthalmitis; Meta-analysis; Open globe; Post-traumatic; Prophylaxis; Systematic review |
| تواريخ الأحداث: | Date Created: 20221117 Latest Revision: 20221121 |
| رمز التحديث: | 20221213 |
| مُعرف محوري في PubMed: | PMC9672185 |
| DOI: | 10.1186/s12348-022-00317-y |
| PMID: | 36396863 |
| قاعدة البيانات: | MEDLINE |
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