دورية أكاديمية
Lisinopril-Induced Small Bowel Angioedema: An Unusual Cause of Severe Abdominal Pain.
العنوان: | Lisinopril-Induced Small Bowel Angioedema: An Unusual Cause of Severe Abdominal Pain. |
---|---|
المؤلفون: | Johnson BW; Department of Anesthesiology, Mayo Clinic, Phoenix, AZ, USA., Rydburg AM; Medical Student, Mayo Clinic Alix School of Medicine, Phoenix, AZ, USA., Do VD; Department of Hospital Internal Medicine, Mayo Clinic, Phoenix, AZ, USA. |
المصدر: | The American journal of case reports [Am J Case Rep] 2022 Nov 22; Vol. 23, pp. e937895. Date of Electronic Publication: 2022 Nov 22. |
نوع المنشور: | Case Reports; Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: International Scientific Information, Inc Country of Publication: United States NLM ID: 101489566 Publication Model: Electronic Cited Medium: Internet ISSN: 1941-5923 (Electronic) Linking ISSN: 19415923 NLM ISO Abbreviation: Am J Case Rep Subsets: MEDLINE |
أسماء مطبوعة: | Publication: <2014- > : Smithtown, NY : International Scientific Information, Inc. Original Publication: Albertson, NY : International Scientific Literature, Inc. |
مواضيع طبية MeSH: | Lisinopril*/adverse effects , Angioedema*/chemically induced , Angioedema*/diagnosis, Female ; Humans ; Middle Aged ; Abdominal Pain/chemically induced ; Abdominal Pain/diagnosis ; Angiotensin-Converting Enzyme Inhibitors/adverse effects ; Abdomen |
مستخلص: | BACKGROUND Angiotensin-converting enzyme inhibitors (ACE-I) are one of the most frequently prescribed classes of medications with the rare adverse effect of angioedema, and isolated small bowel angioedema is a small subset of these cases. Isolated angioedema of the small bowel is a rare adverse effect of this commonly prescribed medication, and it mimics, symptomatically and radiographically, several other illnesses and is often misdiagnosed. While ACE-I are thought to be safe, the risk of angioedema is approximately 0.7%. Isolated small bowel angioedema is often not diagnosed in a timely manner, and misdiagnosis leads to significant morbidity in afflicted patients. CASE REPORT We present the case of a 63-year-old woman with angioedema of the small bowel causing abdominal pain, nausea, vomiting, and diarrhea. Computed tomography demonstrated small bowel edema and ascites. The patient had been taking lisinopril for 7 years prior to presentation and had previously been seen by multiple physicians for abdominal pain. A diagnosis of ACE-I-induced small bowel angioedema was made and lisinopril therapy was immediately stopped. Her symptoms improved with cessation of lisinopril, and follow-up imaging showed resolution of the angioedema 3 months later. CONCLUSIONS The course of ACE-I-induced angioedema is unpredictable and often overlooked as a cause of abdominal pain. It commonly presents soon after starting ACE-I therapy, but can present years after therapy initiation, as in this case. Significant morbidity, including unnecessary exploratory laparotomy, is associated with misdiagnosis of ACE-I-induced angioedema of the small bowel. Prompt recognition and cessation of the offending drug is crucial but often delayed. |
References: | Med J Aust. 1996 Sep 16;165(6):319-21. (PMID: 8862331) J Surg Case Rep. 2020 Oct 09;2020(10):rjaa348. (PMID: 33072254) J Med Cases. 2021 Apr;12(4):138-140. (PMID: 34434446) Emerg Med Clin North Am. 2022 Feb;40(1):79-98. (PMID: 34782093) JAMA. 1997 Jul 16;278(3):232-3. (PMID: 9218671) Emerg Med Clin North Am. 2022 Feb;40(1):99-118. (PMID: 34782094) J Allergy Clin Immunol Pract. 2017 May - Jun;5(3):744-749. (PMID: 28377081) JAAPA. 2020 Aug;33(8):28-31. (PMID: 32740111) J Am Coll Cardiol. 2018 Apr 3;71(13):1474-1482. (PMID: 29598869) Dig Dis Sci. 1997 Apr;42(4):847-50. (PMID: 9125659) Gastroenterology. 2022 Apr;162(4):e12-e13. (PMID: 34390727) J Clin Gastroenterol. 2013 Nov-Dec;47(10):844-9. (PMID: 23751839) Curr Hypertens Rep. 2018 Jun 8;20(7):55. (PMID: 29884969) Allergy Asthma Clin Immunol. 2021 Oct 9;17(1):103. (PMID: 34627363) Intern Med. 1993 May;32(5):424-6. (PMID: 8400508) Drug Saf. 1998 Mar;18(3):171-88. (PMID: 9530537) Acta Cardiol. 2011 Oct;66(5):645-8. (PMID: 22032061) Case Rep Emerg Med. 2021 Feb 13;2021:8853755. (PMID: 33628527) Immunopharmacology. 1999 Oct 15;44(1-2):21-5. (PMID: 10604520) J Pharm Pract. 2018 Feb;31(1):99-103. (PMID: 28125922) J Clin Immunol. 2021 Jan;41(1):163-170. (PMID: 33130967) J Clin Gastroenterol. 2000 Oct;31(3):254-7. (PMID: 11034011) N Engl J Med. 1996 Jun 20;334(25):1641. (PMID: 8628360) Ann Intern Med. 1994 Dec 1;121(11):900. (PMID: 7978713) ANZ J Surg. 2022 Nov;92(11):3110-3111. (PMID: 35199446) AJR Am J Roentgenol. 2011 Aug;197(2):393-8. (PMID: 21785085) Int Immunopharmacol. 2020 Jan;78:106081. (PMID: 31835086) Ann Intern Med. 1992 Aug 1;117(3):234-42. (PMID: 1616218) Lancet. 1998 Jun 6;351(9117):1693-7. (PMID: 9734886) Curr Allergy Asthma Rep. 2012 Feb;12(1):72-8. (PMID: 22127615) |
المشرفين على المادة: | E7199S1YWR (Lisinopril) 0 (Angiotensin-Converting Enzyme Inhibitors) |
تواريخ الأحداث: | Date Created: 20221122 Date Completed: 20221124 Latest Revision: 20221209 |
رمز التحديث: | 20240628 |
مُعرف محوري في PubMed: | PMC9701529 |
DOI: | 10.12659/AJCR.937895 |
PMID: | 36413511 |
قاعدة البيانات: | MEDLINE |
كن أول من يترك تعليقا!