دورية أكاديمية
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Microperimetry assessment in foveal hypoplasia: functional results in a series of pediatric patients.

التفاصيل البيبلوغرافية
العنوان: Microperimetry assessment in foveal hypoplasia: functional results in a series of pediatric patients.
المؤلفون: Bacci GM; Pediatric Ophthalmology Unit, Children's Hospital A. Meyer, University of Florence, Florence, Italy. Electronic address: giacomo.bacci@meyer.it., Morales MU; Academic Ophthalmology, Division of Clinical Neuroscience, School of Medicine, University of Nottingham, Nottingham NG7 2UH, United Kingdom., Febbrini Del Magro E; Pediatric Ophthalmology Unit, Children's Hospital A. Meyer, University of Florence, Florence, Italy., Fortunato P; Pediatric Ophthalmology Unit, Children's Hospital A. Meyer, University of Florence, Florence, Italy., Marziali E; Pediatric Ophthalmology Unit, Children's Hospital A. Meyer, University of Florence, Florence, Italy., Virgili G; Department of Neurosciences, Psychology, Drug Research, and Child Health, Eye Clinic, University of Florence, Florence, Italy., Amoaku W; Academic Ophthalmology, Division of Clinical Neuroscience, School of Medicine, University of Nottingham, Nottingham NG7 2UH, United Kingdom., Caputo R; Pediatric Ophthalmology Unit, Children's Hospital A. Meyer, University of Florence, Florence, Italy.
المصدر: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie [Can J Ophthalmol] 2024 Feb; Vol. 59 (1), pp. e61-e66. Date of Electronic Publication: 2022 Nov 21.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 0045312 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1715-3360 (Electronic) Linking ISSN: 00084182 NLM ISO Abbreviation: Can J Ophthalmol Subsets: MEDLINE
أسماء مطبوعة: Publication: June 2011- : Oxford, England : Elsevier
Original Publication: Montreal, Canadian Ophthalmological Society.
مواضيع طبية MeSH: Visual Field Tests* , Nystagmus, Pathologic*, Humans ; Child ; Retrospective Studies ; Prospective Studies ; Retina ; Vision Disorders ; Tomography, Optical Coherence/methods
مستخلص: Objective: To study the relationships of functional and morphologic retinal parameters in a series of pediatric patients with varying degrees of foveal hypoplasia (FH).
Design: Monocentric observational retrospective study.
Participants: Among 21 pediatric patients, 16 met inclusion criteria, having FH confirmed with spectral-domain optical coherence tomography (SD-OCT) scan METHODS: Data were analyzed retrospectively. Patients able to undergo macular microperimetry (MP) and SD-OCT examinations were included in the analysis. MP and SD-OCT outcomes were compared with FH grading and best-corrected visual acuity (BCVA) using Pearson's correlation.
Results: Thirty-one eyes from 16 patients (mean age 12.4 years) with different degrees of FH were analyzed. Two patients had grade 1, 7 had grade 2, 5 had grade 3, and 2 had grade 4 FH. Clinical nystagmus was present in 8 patients. The correlation between BCVA and SD-OCT data (-0.31) was lower than that found between BCVA and nystagmus (0.64), that for fixation index P1 (-0.60), as well as that for macular sensitivity (-0.63).
Conclusions: Although limited by the small sample, our study confirms the feasibility of automated MP evaluation in pediatric patients with FH. The added value of this work is the provision of data on relationships between anatomic and functional macular measurements acquired with SD-OCT, MP, and BCVA in eyes with various degrees of FH. Larger prospective studies are necessary to confirm these results.
(Copyright © 2022 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights reserved.)
تواريخ الأحداث: Date Created: 20221124 Date Completed: 20240129 Latest Revision: 20240129
رمز التحديث: 20240129
DOI: 10.1016/j.jcjo.2022.10.018
PMID: 36423692
قاعدة البيانات: MEDLINE
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