دورية أكاديمية

Advances in bronchoscopic optical coherence tomography and confocal laser endomicroscopy in pulmonary diseases.

التفاصيل البيبلوغرافية
العنوان: Advances in bronchoscopic optical coherence tomography and confocal laser endomicroscopy in pulmonary diseases.
المؤلفون: Kramer T; Amsterdam UMC, University of Amsterdam, Department of Pulmonary Medicine, Meibergdreef 9, Amsterdam, The Netherlands., Wijsman PC, Kalverda KA, Bonta PI, Annema JT
المصدر: Current opinion in pulmonary medicine [Curr Opin Pulm Med] 2023 Jan 01; Vol. 29 (1), pp. 11-20. Date of Electronic Publication: 2022 Nov 16.
نوع المنشور: Review; Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9503765 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-6971 (Electronic) Linking ISSN: 10705287 NLM ISO Abbreviation: Curr Opin Pulm Med Subsets: MEDLINE
أسماء مطبوعة: Publication: Philadelphia, PA : Lippincott Williams & Wilkins
Original Publication: Philadelphia, PA : Current Science, c1995-
مواضيع طبية MeSH: Tomography, Optical Coherence* , Lung Diseases*/diagnostic imaging, Humans ; Lasers
مستخلص: Purpose of Review: Imaging techniques play a crucial role in the diagnostic work-up of pulmonary diseases but generally lack detailed information on a microscopic level. Optical coherence tomography (OCT) and confocal laser endomicroscopy (CLE) are imaging techniques which provide microscopic images in vivo during bronchoscopy. The purpose of this review is to describe recent advancements in the use of bronchoscopic OCT- and CLE-imaging in pulmonary medicine.
Recent Findings: In recent years, OCT- and CLE-imaging have been evaluated in a wide variety of pulmonary diseases and demonstrated to be complementary to bronchoscopy for real-time, near-histological imaging. Several pulmonary compartments were visualized and characteristic patterns for disease were identified. In thoracic malignancy, OCT- and CLE-imaging can provide characterization of malignant tissue with the ability to identify the optimal sampling area. In interstitial lung disease (ILD), fibrotic patterns were detected by both (PS-) OCT and CLE, complementary to current HRCT-imaging. For obstructive lung diseases, (PS-) OCT enables to detect airway wall structures and remodelling, including changes in the airway smooth muscle and extracellular matrix.
Summary: Bronchoscopic OCT- and CLE-imaging allow high resolution imaging of airways, lung parenchyma, pleura, lung tumours and mediastinal lymph nodes. Although investigational at the moment, promising clinical applications are on the horizon.
(Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.)
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تواريخ الأحداث: Date Created: 20221207 Date Completed: 20221215 Latest Revision: 20230225
رمز التحديث: 20230225
مُعرف محوري في PubMed: PMC9780043
DOI: 10.1097/MCP.0000000000000929
PMID: 36474462
قاعدة البيانات: MEDLINE
الوصف
تدمد:1531-6971
DOI:10.1097/MCP.0000000000000929