دورية أكاديمية
أعرض في EDS

Closed-loop oxygen control for patients with hypoxaemia during hospitalisation: a living systematic review and meta-analysis protocol.

التفاصيل البيبلوغرافية
العنوان: Closed-loop oxygen control for patients with hypoxaemia during hospitalisation: a living systematic review and meta-analysis protocol.
المؤلفون: Mol CG; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., Vieira AGDS; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., Garcia BMSP; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., Pereira EDS; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., Eid RAC; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., Pinto ACPN; Biological and Health Sciences Department, Universidade Federal do Amapá, Macapá, AP, Brazil.; Evidence-Based Health Program, Universidade Federal de São Paulo - UNIFESP, São Paulo, SP, Brazil., Nawa RK; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil ricardo.nawa@einstein.br.
المصدر: BMJ open [BMJ Open] 2022 Dec 12; Vol. 12 (12), pp. e062299. Date of Electronic Publication: 2022 Dec 12.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [London] : BMJ Publishing Group Ltd, 2011-
مواضيع طبية MeSH: Oxygen*/therapeutic use , Hyperoxia*, Humans ; Hypoxia/therapy ; Critical Care ; Hospitalization ; Meta-Analysis as Topic ; Systematic Reviews as Topic
مستخلص: Introduction: Oxygen is the most common drug used in critical care patients to correct episodes of hypoxaemia. The adoption of new technologies in clinical practice, such as closed-loop systems for an automatic oxygen titration, may improve outcomes and reduce the healthcare professionals' workload at the bedside; however, certainty of the evidence regarding the safety and benefits still remains low. We aim to evaluate the effectiveness, efficacy and safety of the closed-loop oxygen control for patients with hypoxaemia during the hospitalisation period by conducting a systematic review and meta-analysis.
Methods and Analysis: MEDLINE, CENTRAL, EMBASE, LILACS, CINAHL and LOVE evidence databases will be searched. Randomised controlled trials and cross-over studies investigating the PICO (Population, Intervention, Comparator and Outcome) framework will be included. The primary outcomes will be the time in the peripheral oxygen saturation target. Secondary outcomes will include time for oxygen weaning time; length of stay; costs; adverse events; mortality; healthcare professionals' workload, and percentage of time with hypoxia and hyperoxia. Two reviewers will independently screen and extract data and perform quality assessment of included studies. The Cochrane risk of bias tool will be used to assess risk of bias. The RevMan V.5.4 software will be used for statistical analysis. Heterogeneity will be analysed using I 2 statistics. Mean difference or standardised mean difference with 95% CI and p value will be used to calculate treatment effect for outcome variables.
Ethics and Dissemination: Ethical approval is not required because this systematic review and meta-analysis is based on previously published data. Final results will be published in peer-reviewed journals and presented at relevant conferences and events.
Prospero Registration Number: CRD42022306033.
Competing Interests: Competing interests: None declared.
(© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
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فهرسة مساهمة: Keywords: Adult intensive & critical care; INTENSIVE & CRITICAL CARE; RESPIRATORY MEDICINE (see Thoracic Medicine)
المشرفين على المادة: S88TT14065 (Oxygen)
تواريخ الأحداث: Date Created: 20221216 Date Completed: 20221219 Latest Revision: 20240909
رمز التحديث: 20240909
مُعرف محوري في PubMed: PMC9748949
DOI: 10.1136/bmjopen-2022-062299
PMID: 36523244
قاعدة البيانات: MEDLINE
الوصف
تدمد:2044-6055
DOI:10.1136/bmjopen-2022-062299