دورية أكاديمية
أعرض في EDS

Clinical Presentation of Myocarditis in the Pediatric Age Group and Predictors of Poor Early and Late Outcomes: Academic Hospital Experience.

التفاصيل البيبلوغرافية
العنوان: Clinical Presentation of Myocarditis in the Pediatric Age Group and Predictors of Poor Early and Late Outcomes: Academic Hospital Experience.
المؤلفون: Alamri AS; Pediatrics, Faculty of Medicine, King Abdulaziz University, Jeddah, SAU., Khayat LT; Pediatrics, Faculty of Medicine, King Abdulaziz University, Jeddah, SAU., Alzahrani AJ; Pediatrics, Faculty of Medicine, King Abdulaziz University, Jeddah, SAU., Kurdi LK; Pediatrics, Faculty of Medicine, King Abdulaziz University, Jeddah, SAU., Alkhameesi NF; Pediatrics, Faculty of Medicine, King Abdulaziz University, Jeddah, SAU., Bahaidarah SA; Pediatrics, Faculty of Medicine, King Abdulaziz University Hospital, Jeddah, SAU.
المصدر: Cureus [Cureus] 2022 Nov 18; Vol. 14 (11), pp. e31643. Date of Electronic Publication: 2022 Nov 18 (Print Publication: 2022).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Cureus, Inc Country of Publication: United States NLM ID: 101596737 Publication Model: eCollection Cited Medium: Print ISSN: 2168-8184 (Print) Linking ISSN: 21688184 NLM ISO Abbreviation: Cureus Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Palo Alto, CA : Cureus, Inc.
مستخلص: Background:  Myocarditis is a leading cause of morbidity and mortality in the pediatric age group and contributes to a wide range of complications, including dilated cardiomyopathy, congestive heart failure, and even death, so early identification and comprehensive management are essential for a favorable outcome.
Objectives:  Summarize the presenting clinical signs and symptoms of pediatric patients with a diagnosis of myocarditis and a poor outcome and correlate the clinical presentation and laboratory and radiographic findings to identify possible predictors of a poor outcome.
Methods:  This retrospective cohort study included all patients who were diagnosed with myocarditis and followed up at King Abdulaziz University Hospital, Jeddah, Saudi Arabia over the 13 years between January 01, 2007, and December 31, 2019. Information on patient demographics, clinical presentation, and non-invasive investigations was obtained. Poor outcomes were defined as death or evidence of left ventricular dysfunction on echocardiography which was evaluated at two points in time as an early outcome and a late outcome.
Results:  Seventeen patients (male 52.9%, female 47.1%) with a median age of 4 ± 4.31 years are included. The most frequent initial complaints were exercise or feeding intolerance, respiratory symptoms, and shortness of breath. On the other hand, hepatomegaly and respiratory distress were the most common clinical signs. All the patients were admitted to the pediatric intensive care unit but only 41% required mechanical ventilation. The presence of a murmur at presentation was significantly correlated with a poor early outcome. Ischemic changes on the electrocardiogram and moderate left ventricular dysfunction on the echocardiogram were significantly correlated with a poor late outcome.
Conclusion:  Diagnosis of myocarditis can be established by a combination of clinical presentation and investigative tools. A murmur, ischemic changes on the electrocardiogram, and left ventricular dysfunction are important predictors of myocarditis in children.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2022, Alamri et al.)
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فهرسة مساهمة: Keywords: children; myocarditis; outcomes; pediatric clinical cardiology; saudi arabia
تواريخ الأحداث: Date Created: 20221221 Latest Revision: 20221222
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC9760052
DOI: 10.7759/cureus.31643
PMID: 36540482
قاعدة البيانات: MEDLINE
الوصف
تدمد:2168-8184
DOI:10.7759/cureus.31643