دورية أكاديمية
أعرض في EDS

Impact of pandemic COVID-19 lockdown on penetrating keratoplasty patients.

التفاصيل البيبلوغرافية
العنوان: Impact of pandemic COVID-19 lockdown on penetrating keratoplasty patients.
المؤلفون: Sharma R; B.W. Lions Superspeciality Eye Hospital, Bengaluru, India., Mamatha B; B.W. Lions Superspeciality Eye Hospital, Bengaluru, India., Sharma S; Department of Statistics, Panjab University, Chandigarh, India., Gyanchand R; B.W. Lions International Eye Bank, Bengaluru, Karnataka, India.
المصدر: Indian journal of ophthalmology [Indian J Ophthalmol] 2023 Jan; Vol. 71 (1), pp. 95-100.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Medknow Publications Country of Publication: India NLM ID: 0405376 Publication Model: Print Cited Medium: Internet ISSN: 1998-3689 (Electronic) Linking ISSN: 03014738 NLM ISO Abbreviation: Indian J Ophthalmol Subsets: MEDLINE
أسماء مطبوعة: Publication: Mumbai : Medknow Publications
Original Publication: Bombay : All-India Ophthalmological Society
مواضيع طبية MeSH: COVID-19*/epidemiology , Corneal Diseases*/epidemiology , Corneal Diseases*/surgery , Corneal Diseases*/diagnosis, Male ; Female ; Humans ; Young Adult ; Adult ; Middle Aged ; Keratoplasty, Penetrating/methods ; Retrospective Studies ; Pandemics ; Communicable Disease Control ; Graft Rejection/epidemiology ; Treatment Outcome ; Graft Survival
مستخلص: Purpose: To study the impact of the COVID-19 lockdown on the regular follow-up of keratoplasty patients.
Methods: This retrospective interventional case series included 30 patients who had immunological corneal endothelial rejection out of 190 patients who came for post-PKP follow-up between September 15, 2019, and September 30, 2020. The demographics, primary diagnosis, surgical technique, time of presentation, recovery of graft, associated ocular problems, and visual acuity at 1 month were analyzed. Forward stepwise (likelihood ratio) binary logistic regression was used to find significant variables.
Results: The study population had 19 males (63.33%) and 11 females (36.67%). The mean age of the study group was 42.83 ± 18.89 (8-80) years. Of 30 patients, 19 (63.3%) presented before and 11 (36.7%) after the COVID-19 lockdown. Overall, 23 (77%) showed a reversal of graft rejection. Logistic regression showed that preoperative indications, large-sized grafts, and deep corneal vascularization were significant risk factors for non-resolution of graft rejection. It was noted that patients who presented to the hospital late had poor recovery (P = 0.002). The delay in the presentation was a significant risk factor for non-resolution of graft rejection (P < 0.01). Z-test for proportions revealed that the difference in the non-resolution of rejection on immediate or delayed treatment in patients presenting during lockdown (P = 0.002) was significant.
Conclusion: This article is to highlight the impact of the COVID-19 lockdown on graft rejection recovery of PKP patients due to delays in follow-up. Early treatment helps in the recovery of graft transparency and the reversal of immunological graft rejection. Also, primary diagnosis, deep vascularization, and large-sized grafts were significant risk factors for non-resolution of graft rejection.
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فهرسة مساهمة: Keywords: COVID-19; corneal graft rejection; penetrating keratoplasty
تواريخ الأحداث: Date Created: 20230102 Date Completed: 20230103 Latest Revision: 20230505
رمز التحديث: 20240829
مُعرف محوري في PubMed: PMC10155521
DOI: 10.4103/ijo.IJO_1190_22
PMID: 36588216
قاعدة البيانات: MEDLINE
الوصف
تدمد:1998-3689
DOI:10.4103/ijo.IJO_1190_22