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Monte Carlo Study on Dose Distributions Around 192 Ir, 169 Yb, and 125 I Brachytherapy Sources Using EGSnrc-based egs_brachy User-code.

التفاصيل البيبلوغرافية
العنوان: Monte Carlo Study on Dose Distributions Around 192 Ir, 169 Yb, and 125 I Brachytherapy Sources Using EGSnrc-based egs_brachy User-code.
المؤلفون: Mishra S; Division of Radiological Physics and Advisory, Health Safety and Environment Group, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India., Mishra B; Division of Radiological Safety, Atomic Energy Regulatory Board, Mumbai, Maharashtra, India., Selvam TP; Division of Radiological Physics and Advisory, Health Safety and Environment Group, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India.; Homi Bhabha National Institute, Mumbai, Maharashtra, India., Deshpande S; Department of Radiation Oncology, P. D. Hinduja National Hospital and MRC, Mumbai, Maharashtra, India., Pathan MS; Division of Radiological Physics and Advisory, Health Safety and Environment Group, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India., Kumar R; Division of Radiological Physics and Advisory, Health Safety and Environment Group, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India.
المصدر: Journal of medical physics [J Med Phys] 2022 Jul-Sep; Vol. 47 (3), pp. 270-278. Date of Electronic Publication: 2022 Nov 08.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Medknow Publications Country of Publication: India NLM ID: 9441104 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0971-6203 (Print) Linking ISSN: 09716203 NLM ISO Abbreviation: J Med Phys Subsets: PubMed not MEDLINE
أسماء مطبوعة: Publication: Mumbai : Medknow Publications
Original Publication: Bombay : The Association, [1994-
مستخلص: Introduction: As per the recommendations of the American Association of Physicists in Medicine Task Group 43, Monte Carlo (MC) investigators should reproduce previously published dose distributions whenever new features of the code are explored. The purpose of the present study is to benchmark the TG-43 dosimetric parameters calculated using the new MC user-code egs_brachy of EGSnrc code system for three different radionuclides 192 Ir, 169 Yb, and 125 I which represent high-, intermediate-, and low-energy sources, respectively.
Materials and Methods: Brachytherapy sources investigated in this study are high-dose rate (HDR) 192 Ir VariSource (Model VS2000), 169 Yb HDR (Model 4140), and 125 I -low-dose-rate (LDR) (Model OcuProsta). The TG-43 dosimetric parameters such as air-kerma strength, S k , dose rate constant, Λ, radial dose function, g(r) and anisotropy function, F(r, θ ) and two-dimensional (2D) absorbed dose rate data (along-away table) are calculated in a cylindrical water phantom of mass density 0.998 g/cm 3 using the MC code egs_brachy. Dimensions of phantom considered for 192 Ir VS2000 and 169 Yb sources are 80 cm diameter ×80 cm height, whereas for 125 I OcuProsta source, 30 cm diameter ×30 cm height cylindrical water phantom is considered for MC calculations.
Results: The dosimetric parameters calculated using egs_brachy are compared against the values published in the literature. The calculated values of dose rate constants from this study agree with the published values within statistical uncertainties for all investigated sources. Good agreement is found between the egs_brachy calculated radial dose functions, g(r), anisotropy functions, and 2D dose rate data with the published values (within 2%) for the same phantom dimensions. For 192 Ir VS2000 source, difference of about 28% is observed in g(r) value at 18 cm from the source which is due to differences in the phantom dimensions.
Conclusion: The study validates TG-43 dose parameters calculated using egs_brachy for 192 Ir, 169 Yb, and 125 I brachytherapy sources with the values published in the literature.
Competing Interests: There are no conflicts of interest.
(Copyright: © 2022 Journal of Medical Physics.)
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فهرسة مساهمة: Keywords: Brachytherapy; EGSnrc code system; Monte Carlo; TG-43 dosimetry; egs_brachy
تواريخ الأحداث: Date Created: 20230123 Latest Revision: 20231031
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC9847004
DOI: 10.4103/jmp.jmp_16_22
PMID: 36684701
قاعدة البيانات: MEDLINE
الوصف
تدمد:0971-6203
DOI:10.4103/jmp.jmp_16_22