دورية أكاديمية
Pelgipeptins, a Nonribosomal Lipopeptide Family, Show Larvicidal Activity against Vectors Transmitting Viruses.
| العنوان: | Pelgipeptins, a Nonribosomal Lipopeptide Family, Show Larvicidal Activity against Vectors Transmitting Viruses. |
|---|---|
| المؤلفون: | da Costa RA; Graduate Program in Genomic Sciences and Biotechnology, Universidade Católica de Brasília, SGAN 916, Brasília, DF 70790-160, Brazil., Dutra TTB; Graduate Program in Genomic Sciences and Biotechnology, Universidade Católica de Brasília, SGAN 916, Brasília, DF 70790-160, Brazil., Pereira Costa Andrade IE; Graduate Program in Genomic Sciences and Biotechnology, Universidade Católica de Brasília, SGAN 916, Brasília, DF 70790-160, Brazil., Monnerat RG; Laboratório de Bactérias Entomopatogênicas, Embrapa Recursos Genéticos e Biotecnologia, Av. W5 Norte, Brasília, DF 70770-917, Brazil., Barreto CC; Graduate Program in Genomic Sciences and Biotechnology, Universidade Católica de Brasília, SGAN 916, Brasília, DF 70790-160, Brazil., Dias SC; Graduate Program in Genomic Sciences and Biotechnology, Universidade Católica de Brasília, SGAN 916, Brasília, DF 70790-160, Brazil.; Graduate Program in Animal Biology, Universidade de Brasília, Campus Darcy Ribeiro, Brasília, DF 70910-900, Brazil. |
| المصدر: | Journal of agricultural and food chemistry [J Agric Food Chem] 2023 Feb 01; Vol. 71 (4), pp. 1921-1929. Date of Electronic Publication: 2023 Jan 23. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5118 (Electronic) Linking ISSN: 00218561 NLM ISO Abbreviation: J Agric Food Chem Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Washington, American Chemical Society. |
| مواضيع طبية MeSH: | Anopheles*/drug effects , Bacillaceae*/chemistry , Bacillus thuringiensis*/chemistry , Culex*/drug effects , Insecticides*/pharmacology, Animals ; Larva/drug effects ; Lipopeptides/pharmacology ; Mosquito Vectors ; Viruses |
| مستخلص: | Aedes aegypti and Culex quinquefasciatus are vectors of numerous diseases of worldwide public importance, such as arboviruses and filariasis. The main strategy for controlling these vectors is the use of chemicals, which can induce the appearance of resistant insects. The use of Bacillus thuringiensis ( Bt ) and Lysinibacillus sphaericus ( Ls ) with larvicidal activity against arboviral-transmitting insects has been successful in many studies. In contrast, the use and knowledge of peptides with insecticidal activity are so far scarce. In this work, 25 peptides and 5 strains of each bacterial species were prospected individually or together regarding their insecticidal activity. Initially, in vitro assays of cellular cytotoxicity of the peptides against SF21 cells of Spodoptera frugiperda were performed. The peptides Polybia-MPII and pelgipeptin caused 69 and 60% of cell mortality, respectively, at the concentration of 10 μM. Thus, they were evaluated in vivo against second-stage larvae of the two Culicidae. However, in the in vivo bioassays, only pelgipeptin showed larvicidal mortality against both larvae (LC |
| فهرسة مساهمة: | Keywords: Aedes aegypti; Culex quinquefasciatus; biocontrol; larvicidal peptides; nonribosomal lipopeptide |
| المشرفين على المادة: | 0 (Insecticides) 0 (Lipopeptides) |
| تواريخ الأحداث: | Date Created: 20230123 Date Completed: 20230206 Latest Revision: 20230206 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1021/acs.jafc.2c05458 |
| PMID: | 36688912 |
| قاعدة البيانات: | MEDLINE |
Find this issue from the American Chemical Society كن أول من يترك تعليقا!