دورية أكاديمية
أعرض في EDS

Health Status Outcomes in Older Adults Undergoing Chronic Total Occlusion Percutaneous Coronary Intervention.

التفاصيل البيبلوغرافية
العنوان: Health Status Outcomes in Older Adults Undergoing Chronic Total Occlusion Percutaneous Coronary Intervention.
المؤلفون: Nguyen DD; Saint Luke's Mid America Heart Institute Kansas City MO.; University of Missouri-Kansas City Kansas City MO., Gosch KL; Saint Luke's Mid America Heart Institute Kansas City MO., El-Zein R; Saint Luke's Mid America Heart Institute Kansas City MO.; University of Missouri-Kansas City Kansas City MO., Chan PS; Saint Luke's Mid America Heart Institute Kansas City MO.; University of Missouri-Kansas City Kansas City MO., Lombardi WL; University of Washington Medical Center Seattle WA., Karmpaliotis D; Morristown Medical Center Morristown NJ., Spertus JA; Saint Luke's Mid America Heart Institute Kansas City MO.; University of Missouri-Kansas City Kansas City MO., Wyman RM; Torrance Memorial Medical Center Torrance CA., Nicholson WJ; Emory University Atlanta GA., Moses JW; Columbia University Medical Center New York NY.; Saint Francis Heart Center Roslyn NY., Grantham JA; Saint Luke's Mid America Heart Institute Kansas City MO.; University of Missouri-Kansas City Kansas City MO., Salisbury AC; Saint Luke's Mid America Heart Institute Kansas City MO.; University of Missouri-Kansas City Kansas City MO.
مؤلفون مشاركون: OPEN‐CTO Study Group *
المصدر: Journal of the American Heart Association [J Am Heart Assoc] 2023 Feb 07; Vol. 12 (3), pp. e027915. Date of Electronic Publication: 2023 Jan 31.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural
اللغة: English
بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-9980 (Electronic) Linking ISSN: 20479980 NLM ISO Abbreviation: J Am Heart Assoc Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Oxford : Wiley-Blackwell
مواضيع طبية MeSH: Percutaneous Coronary Intervention*/adverse effects , Coronary Occlusion*/diagnosis , Coronary Occlusion*/surgery, Humans ; Aged ; Aged, 80 and over ; Treatment Outcome ; Chronic Disease ; Angina Pectoris/etiology ; Health Status ; Registries ; Risk Factors ; Coronary Angiography
مستخلص: Background Although chronic total occlusions (CTOs) are common in older adults, they are less likely to be offered CTO percutaneous coronary intervention for angina relief than younger adults. The health status impact of CTO percutaneous coronary intervention in adults aged ≥75 years has not been studied. We sought to compare technical success rates and angina-related health status outcomes at 12 months between adults aged ≥75 and <75 years in the OPEN-CTO (Outcomes, Patient Health Status, and Efficiency in Chronic Total Occlusion) registry. Methods and Results Angina-related health status was assessed with the Seattle Angina Questionnaire (score range 0-100, higher scores denote less angina). Technical success rates were compared using hierarchical modified Poisson regression, and 12-month health status was compared using hierarchical multivariable linear regression between adults aged ≥75 and <75 years. Among 1000 participants, 19.8% were ≥75 years with a mean age of 79.5±4.1 years. Age ≥75 years was associated with a lower likelihood of technical success (adjusted risk ratio=0.92 [95% CI, 0.86-0.99; P =0.02]) and numerically higher rates of in-hospital major adverse cardiovascular events (9.1% versus 5.9%, P =0.10). There was no difference in Seattle Angina Questionnaire Summary Score at 12 months between adults aged ≥75 and <75 years (adjusted difference=0.9 [95% CI, -1.4 to 3.1; P =0.44]). Conclusions Despite modestly lower success rates and higher complication rates, adults aged ≥75 years experienced angina-related health status benefits after CTO-percutaneous coronary intervention that were similar in magnitude to adults aged <75 years. CTO percutaneous coronary intervention should not be withheld based on age alone in otherwise appropriate candidates.
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معلومات مُعتمدة: R01 HL160734 United States HL NHLBI NIH HHS; T32 HL110837 United States HL NHLBI NIH HHS
فهرسة مساهمة: Investigator: JA Grantham; SL Cook; P Doshi; R Federici; D Karmpaliotis; WL Lombardi; JW Moses; WJ Nicholson; A Pershad; AJ Spaedy; RM Wyman
Keywords: chronic total occlusion; health status; older adults; percutaneous coronary intervention
تواريخ الأحداث: Date Created: 20230131 Date Completed: 20230208 Latest Revision: 20231004
رمز التحديث: 20231004
مُعرف محوري في PubMed: PMC9973646
DOI: 10.1161/JAHA.122.027915
PMID: 36718862
قاعدة البيانات: MEDLINE
الوصف
تدمد:2047-9980
DOI:10.1161/JAHA.122.027915