دورية أكاديمية
Efficacy of Elimination Diets in Eosinophilic Esophagitis: A Systematic Review and Meta-analysis.
| العنوان: | Efficacy of Elimination Diets in Eosinophilic Esophagitis: A Systematic Review and Meta-analysis. |
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| المؤلفون: | Mayerhofer C; Department of Paediatrics I, Medical University of Innsbruck, Innsbruck, Austria., Kavallar AM; Department of Paediatrics I, Medical University of Innsbruck, Innsbruck, Austria., Aldrian D; Department of Paediatrics I, Medical University of Innsbruck, Innsbruck, Austria., Lindner AK; Department of Urology, Medical University Innsbruck, Innsbruck, Austria., Müller T; Department of Paediatrics I, Medical University of Innsbruck, Innsbruck, Austria., Vogel GF; Department of Paediatrics I, Medical University of Innsbruck, Innsbruck, Austria; Institute of Cell Biology, Medical University of Innsbruck, Innsbruck, Austria. Electronic address: georg.vogel@i-med.ac.at. |
| المصدر: | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association [Clin Gastroenterol Hepatol] 2023 Aug; Vol. 21 (9), pp. 2197-2210.e3. Date of Electronic Publication: 2023 Jan 31. |
| نوع المنشور: | Journal Article; Meta-Analysis; Systematic Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: W.B. Saunders for the American Gastroenterological Association Country of Publication: United States NLM ID: 101160775 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1542-7714 (Electronic) Linking ISSN: 15423565 NLM ISO Abbreviation: Clin Gastroenterol Hepatol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Philadelphia, PA : W.B. Saunders for the American Gastroenterological Association, 2003- |
| مواضيع طبية MeSH: | Eosinophilic Esophagitis*/pathology, Child ; Humans ; Allergens ; Diet/methods ; Elimination Diets ; Food ; Treatment Outcome |
| مستخلص: | Background & Aims: Eosinophilic esophagitis (EoE) can be treated by proton pump inhibitors, topical corticosteroids, or dietary measures. This study systematically assessed the efficacy of 4 major dietary treatment regimens in EoE, updating the evidence presented in a meta-analysis from 2014. Methods: Electronic databases such as PubMed, Scopus, and Web of Science, and other sources were searched up to September 2022 to identify studies on dietary treatment of EoE. Based on histologic remission criteria, the efficacy of these treatments was pooled and analyzed with respect to the type of dietary regimen: 6-food elimination diet (SFED), 4-food elimination diet (FFED), 1-food elimination diet (OFED), and a targeted elimination diet (TED). Clinical response rates, food sensitization, and efficacies for a pediatric subpopulation were calculated. Influencing variables on efficacies were estimated via meta-regression analyses. Results: Thirty-four studies with 1762 patients met the inclusion criteria. The overall rate of histologic remission was 53.8% (95% CI, 48.0%-59.6%), and in the individual dietary groups was 61.3% (95% CI, 53.0%-69.3%) for SFED, 49.4% (95% CI, 32.5%-66.3%) for FFED, 51.4% (95% CI, 42.6%-60.1%) for OFED, and 45.7% (95% CI, 32.0%-59.7%) for TED. Dietary regimen and patient age did not significantly affect rates of histologic remission. The overall rate of clinical response was 80.8% (95% CI, 72.3%-88.2%), with response rates of 92.8% (95% CI, 81.2%-99.6%) for SFED, 74.1% (95% CI, 49.8%-92.6%) for FFED, 87.1% (95% CI, 58.4%-99.9%) for OFED, and 69.0% (95% CI, 50.2%85.3%) for TED. Conclusions: Dietary therapy is an effective treatment for EoE patients of any age. The current results could support a trend toward less-restrictive dietary regimens as a primary treatment option. (Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Dietary Treatment; Eosinophilic Esophagitis; Histological Remission; Meta-Analysis; Pediatric |
| المشرفين على المادة: | 0 (Allergens) |
| تواريخ الأحداث: | Date Created: 20230202 Date Completed: 20230801 Latest Revision: 20230801 |
| رمز التحديث: | 20230802 |
| DOI: | 10.1016/j.cgh.2023.01.019 |
| PMID: | 36731591 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1542-7714 |
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| DOI: | 10.1016/j.cgh.2023.01.019 |