دورية أكاديمية
Food Allergy Management Practices Utilizing Individual Patient Thresholds: A Work Group Report of the AAAAI Adverse Reactions to Foods Committee.
| العنوان: | Food Allergy Management Practices Utilizing Individual Patient Thresholds: A Work Group Report of the AAAAI Adverse Reactions to Foods Committee. |
|---|---|
| المؤلفون: | Oriel RC; Division of Pediatric Allergy and Immunology, Jaffe Food Allergy Institute, Icahn School of Medicine at Mount Sinai, New York, NY., Shah A; Division of Pediatric Allergy and Immunology, Jaffe Food Allergy Institute, Icahn School of Medicine at Mount Sinai, New York, NY., Anagnostou A; Division of Allergy, Immunology and Retrovirology, Baylor College of Medicine & Texas Children's Hospital, Houston, Texas., Greenhawt M; Section of Allergy and Immunology, Children's Hospital Colorado, Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colo., Khan F; Department of Pediatrics, Division of Allergy and Immunology, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, Ill., Leeds S; Department of Pediatrics, Yale School of Medicine, New Haven, Conn., Ravindran M; Department of Medicine, Emory University School of Medicine, Atlanta, Ga., Stoffels G; Division of Biostatistics, Icahn School of Medicine at Mount Sinai, New York, NY., Vickery BP; Department of Pediatrics, Emory University School of Medicine, Atlanta, Ga., Virkud YV; Department of Pediatrics, University of North Carolina - Chapel Hill, Chapel Hill, NC., Sicherer SH; Division of Pediatric Allergy and Immunology, Jaffe Food Allergy Institute, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address: scott.sicherer@mssm.edu. |
| المصدر: | The journal of allergy and clinical immunology. In practice [J Allergy Clin Immunol Pract] 2023 Apr; Vol. 11 (4), pp. 1083-1086.e1. Date of Electronic Publication: 2023 Feb 10. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101597220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2201 (Electronic) NLM ISO Abbreviation: J Allergy Clin Immunol Pract Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: New York, NY : Elsevier Inc., [2013]- |
| مواضيع طبية MeSH: | Peanut Hypersensitivity* , Food Hypersensitivity*/epidemiology , Food Hypersensitivity*/therapy, Humans ; Food ; Allergens ; Arachis |
| مستخلص: | The paradigm for food allergy management has been strict avoidance of the food allergen. There is literature supporting a "high-threshold" phenotype, those who tolerate a small-to-modest amount of allergen but react to larger amounts. There is no consensus for best practice for these "high-threshold" individuals. We sought to understand management practices of "high-threshold" reactors using a survey that was distributed to a random sample of fellows and members of the American Academy of Allergy, Asthma, and Immunology. There were 89 respondents from the United States and Canada (11% response rate), with 64 (72%) answering all questions. Participants worked in private (52%) and academic practice (38%) and saw a median of 30 food allergic patients monthly. Eighty-one percent of respondents reported management strategies other than strict avoidance. When threshold was known, strategies ranged from allowing ingestion up to a specified amount (57%), proactively advising ingestion to a certain amount (56%), or oral immunotherapy (47%). Participants were more likely to choose a permissive approach for a mild reaction in a high-threshold milk-allergic patient compared with a peanut-allergic patient (83% vs 71%, p=.01). Important factors that influenced the approach included severity of reaction (52%), comfort with family/patient using emergency medications (42%), and family/patient preferences (41%). These survey results suggest that food allergy management recommendations are no longer binary in nature, with clinicians solely recommending avoidance for those who are allergic and ingestion for those who may not be. (Copyright © 2023 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Allergen; Food allergy; High threshold; Oral food challenge; Oral immunotherapy; Strict avoidance |
| المشرفين على المادة: | 0 (Allergens) |
| تواريخ الأحداث: | Date Created: 20230211 Date Completed: 20230411 Latest Revision: 20230513 |
| رمز التحديث: | 20230514 |
| DOI: | 10.1016/j.jaip.2023.01.045 |
| PMID: | 36773718 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 2213-2201 |
|---|---|
| DOI: | 10.1016/j.jaip.2023.01.045 |